Brand Dispensette® S Organic Bottle Top Dispenser, Model 4630141

Overview

The Brand Dispensette® S Organic Bottle Top Dispenser (Model 4630141) is a precision-engineered, manually operated liquid handling device designed for safe, accurate, and repeatable dispensing of aggressive organic solvents, concentrated acids, and bases in analytical, quality control, and synthetic chemistry laboratories. Based on the proven piston-driven positive displacement principle, it eliminates reliance on gravity or air displacement—ensuring consistent volumetric delivery independent of operator technique, liquid density, or vapor pressure. Its core architecture adheres to ISO 8655-3 (volumetric apparatus — piston-operated burettes) and incorporates design elements validated under GLP-compliant workflows. The unit is manufactured in Germany and certified with the DE-M mark, affirming compliance with EU metrological requirements for calibrated measuring instruments.

Key Features

• Chemical-resistant construction using high-purity ETFE, FEP, PFA, and polypropylene—validated for compatibility with chlorinated hydrocarbons (e.g., trichlorotrifluoroethane), fluorinated solvents, concentrated HCl and HNO₃ (excluding HF), trifluoroacetic acid (TFA), tetrahydrofuran (THF), and peroxides.
• Vernier-adjustable volume setting mechanism with toothed rail guide enables rapid, tactile volume selection across the full 1–10 mL range in 0.2 mL increments; calibration verified using traceable gravimetric methods per ISO 8655-6.
• Integrated safety discharge system prevents unintended liquid release when the dispensing tip is not fully seated—reducing exposure risk during setup or maintenance.
• Optional integrated safety valve (Order No. 706090) provides internal bubble venting during priming, minimizing reagent waste and preserving volumetric accuracy by eliminating air entrapment in the piston chamber.
• Adjustable immersion tube with telescopic design accommodates bottle heights from 125 mm to 240 mm; 360° rotational mounting ensures label visibility and ergonomic orientation regardless of dispensing direction.
• Includes three universal adapter sleeves (GL45 standard configuration) supporting GL24/25, GL28/S28, GL32/33, GL38, and S40 thread specifications—enabling seamless integration across diverse reagent container formats.
• PTFE-coated dispensing tube (800 mm length, optional Order No. 707925/707926) features an ergonomically shaped safety handle for extended-reach applications and precise insertion into narrow-neck vessels.

Sample Compatibility & Compliance

The Dispensette® S Organic is engineered for routine use with low-to-medium volatility liquids exhibiting kinematic viscosities up to 500 mm²/s and densities ≤2.2 g/cm³. It operates reliably within ambient temperature ranges of +15 °C to +40 °C; operation outside this range requires prior validation and may affect volumetric fidelity. The device is explicitly excluded for use with hydrofluoric acid (HF), oxidizing peroxides beyond manufacturer-specified stability limits, or liquids exceeding 600 mbar vapor pressure at operating temperature. All wetted materials comply with USP Class VI biocompatibility testing and meet REACH and RoHS directives. Device documentation includes a factory calibration certificate traceable to PTB (Physikalisch-Technische Bundesanstalt), satisfying audit requirements under ISO/IEC 17025, FDA 21 CFR Part 11 (when paired with compliant data logging systems), and GMP Annex 11 environments where manual dispensing records are maintained.

Software & Data Management

As a manually operated, analog-dispensing instrument, the Dispensette® S Organic does not incorporate embedded electronics, firmware, or digital interfaces. Volume setting, actuation, and verification are performed mechanically—ensuring operational independence from power sources, software updates, or cybersecurity protocols. Calibration records, usage logs, and maintenance entries are maintained externally in laboratory notebooks or LIMS platforms per institutional SOPs. Optional accessories—including certified calibration weights and gravimetric test kits (e.g., Brand Catalog No. 707930 drying tube for moisture-sensitive applications)—support periodic user verification aligned with ISO/IEC 17025 clause 6.5.2 (verification of equipment suitability).

Applications

• Accurate preparation of calibration standards and reference solutions containing TFA, THF, DCM, or concentrated mineral acids in HPLC, GC, and ICP-MS sample workflows.
• Controlled reagent addition in synthetic organic reactions where stoichiometric precision and operator safety are critical—especially under inert atmosphere or fume hood conditions.
• Dispensing viscous or volatile solvents into reaction flasks, vials, or microplates without splashing or aerosol generation.
• Quality assurance testing in pharmaceutical manufacturing (e.g., excipient dilution, titrant preparation) under cGMP guidelines requiring documented volumetric consistency.
• Academic teaching labs requiring robust, intuitive tools for student training in quantitative liquid handling fundamentals and chemical hazard mitigation.

FAQ

What types of liquids is the Dispensette® S Organic (4630141) specifically rated for?
It is validated for organic solvents (including chlorinated and fluorinated compounds), concentrated hydrochloric and nitric acids (excluding HF), trifluoroacetic acid, tetrahydrofuran, and stable peroxide solutions.
Can this dispenser be used with hydrofluoric acid (HF)?
No—HF is incompatible with all wetted materials in this model and poses unacceptable corrosion and safety risks.
Is the 0.1% accuracy specification guaranteed across the entire 1–10 mL range?
Accuracy is specified as ±0.1% of set volume per ISO 8655-3; however, absolute error increases proportionally with volume—e.g., ±0.01 mL at 10 mL, ±0.001 mL at 1 mL.
Does the device require periodic recalibration by an accredited lab?
While factory calibration is provided, users must perform interval verification per internal SOPs—typically before each shift or daily for high-precision applications—using traceable gravimetric methods.
Are replacement parts such as valves or seals available separately?
Yes—Brand offers genuine OEM service kits (e.g., Seal Kit No. 707900) and individual components with documented lot traceability and material certifications.