BRAND Titrette Digital Burette Dispenser Model 4760141

Overview

The BRAND Titrette Digital Burette Dispenser Model 4760141 is a precision-engineered, motor-assisted liquid dispensing instrument designed to replace traditional glass burettes in analytical titration workflows. Unlike conventional manual burettes, the Titrette integrates electronic control with mechanical fluid displacement via a high-tolerance piston and PTFE-coated syringe barrel, operating on positive displacement principles compliant with ISO 8655-3 for Class A volumetric accuracy. Its core function is repeatable, user-directed volumetric delivery across defined ranges—10 mL, 25 mL, or 50 mL—with an accuracy of ±0.1% of full scale and repeatability better than ±0.05%. The device does not rely on gravimetric feedback or external sensors; instead, it achieves metrological reliability through factory-traceable piston travel calibration, linear step-motor actuation, and temperature-compensated volume calculation algorithms. Designed for ISO/IEC 17025-accredited laboratories and regulated environments, the Titrette supports audit-ready operation through built-in calibration logging, configurable decimal resolution (0.001–0.01 mL), and optional electronic data capture.

Key Features

• EasyCal™ single-point calibration system with programmable calibration interval alerts — eliminates need for multi-point gravimetric verification during routine use
• Intuitive bidirectional manual control: clockwise rotation aspirates, counterclockwise dispenses — no mode-switching buttons required
• Telescopic dispensing tube (170–330 mm) with integrated reflux channel for bubble-free aspiration and drip-free dispensing
• Dual amber LCD display with independent windows showing set volume and delivered volume — optimized for low-glare, UV-sensitive workspaces
• Automatic power-off after 15 minutes of inactivity, extendable via software setting — conserves battery life without compromising readiness
• Modular, tool-free disassembly: all wetted parts (piston, barrel, valve, adapters) are accessible for cleaning, sterilization (autoclavable up to 121°C), or replacement
• Three chemically resistant polypropylene bottle adapters included (GL 45/32, GL 45/S 40, GL 32/NS 29/32) — compatible with standard reagent bottles and narrow-neck containers

Sample Compatibility & Compliance

The Titrette 4760141 is validated for aqueous, alcoholic, and moderately aggressive organic solvents (e.g., acetone, acetonitrile, methanol, 1 M HCl, 1 M NaOH) when used with standard PTFE/PP wetted materials. It is not recommended for strong oxidizers (e.g., concentrated HNO₃, perchloric acid) or halogenated hydrocarbons without prior compatibility testing. All electrical components comply with EN 61010-1 (Safety Requirements for Electrical Equipment for Measurement, Control, and Laboratory Use) and EN 61326-1 (EMC for laboratory equipment). The DE-M marking confirms conformity with German metrological regulations under the Eichgesetz, ensuring traceability to PTB (Physikalisch-Technische Bundesanstalt). Performance certification documentation—including as-delivered accuracy verification and linearity test reports—is supplied with each unit and satisfies GLP/GMP documentation requirements for method validation and instrument qualification.

Software & Data Management

While the 4760141 base model operates standalone, optional RS232 interface (available via accessory kit 4760241) enables direct serial communication with LIMS or ELN platforms. Data output includes timestamped delivery events, cumulative volume, calibration status, and battery level — formatted as ASCII strings compatible with common laboratory software (e.g., LabWare, STARLIMS, ChemStation). The interface supports command-driven control (e.g., “DISP 12.345”, “CAL START”) and automatic log export upon connection. All calibration entries—including date, operator ID (manually entered), and deviation values—are stored in non-volatile memory with write-protection logic to prevent accidental overwrites. Audit trail functionality meets FDA 21 CFR Part 11 requirements when paired with compliant host software and user access controls.

Applications

• Standardized acid-base, redox, and complexometric titrations in QC/QA labs (e.g., USP , ASTM E200, ISO 9001 Annex A.5)
• Preparation of certified reference material dilutions requiring ≤0.1% volumetric uncertainty
• Method transfer between R&D and production where manual burette variability must be eliminated
• Training environments: real-time visual feedback reduces learning curve versus glassware-based techniques
• Environmental testing labs performing EPA Method 365.2 (phosphate determination) or ISO 9963-1 (alkalinity titration)
• Pharmaceutical stability studies requiring reproducible reagent addition across multiple timepoints

FAQ

What standards does the Titrette 4760141 comply with for volumetric accuracy?
It conforms to ISO 8655-3:2022 Class A specifications for piston burettes, with factory-certified accuracy of ±0.1% of full scale and repeatability ≤±0.05%. Each unit ships with a PTB-traceable performance certificate.
Can the Titrette be calibrated in-house without external equipment?
Yes — the EasyCal™ system requires only a single certified weight (e.g., 10 g stainless steel mass) and distilled water at ambient temperature. Full calibration takes <90 seconds and stores results with date/time stamp.
Is the telescopic tube autoclavable?
The dispensing tube assembly (including reflux channel) is autoclavable at 121°C for 20 minutes. The main housing and electronics are not autoclavable and must remain external to sterilization cycles.
How is data integrity ensured during RS232 transmission?
All serial commands include checksum validation (ASCII CR/LF + XOR), and the device echoes every received instruction before execution — enabling host-side verification of command receipt and execution status.
What maintenance intervals are recommended for routine use?
Daily visual inspection and wiping of the piston seal; monthly cleaning of the valve seat and barrel with ethanol; annual full recalibration — intervals may be extended under documented risk assessment per ISO/IEC 17025 clause 6.4.6.