Brandtech Dispensette® S Organic Bottle Top Dispenser Model 4630351
| Brand | Brandtech® |
|---|---|
| Origin | Germany |
| Model | 4630351 |
| Type | Digital Adjustable Bottle Top Dispenser |
| Volume Range | 25–50 mL |
| Minimum Increment | 0.1 mL |
| Accuracy | ±0.5% |
| Precision (Repeatability) | ±0.1% |
| Operating Temperature | +15 °C to +40 °C |
| Maximum Vapor Pressure | 600 mbar (slow aspiration required above 300 mbar) |
| Max. Kinematic Viscosity | 500 mm²/s |
| Max. Liquid Density | 2.2 g/cm³ |
| Chemical Compatibility | Chlorinated & fluorinated hydrocarbons (e.g., CFC-113, DCM), concentrated HCl & HNO₃ (excluding HF), TFA, THF, peroxides |
Overview
The Brandtech Dispensette® S Organic Bottle Top Dispenser Model 4630351 is an ergonomically engineered, manually operated precision liquid handling device designed for safe, repeatable, and contamination-free dispensing of aggressive organic solvents and corrosive reagents directly from laboratory reagent bottles. Based on the proven piston-driven positive displacement principle, it eliminates reliance on air displacement or gravity flow—ensuring consistent volumetric delivery independent of operator technique, liquid density, or vapor pressure. Its all-PFA and ETFE-wetted path, combined with a chemically resistant yellow housing and PTFE-coated piston seal, provides validated compatibility with high-volatility, low-surface-tension, and oxidizing liquids—including chlorinated solvents (e.g., dichloromethane, chloroform), fluorinated compounds (e.g., CFC-113), strong mineral acids (HCl, HNO₃), trifluoroacetic acid (TFA), tetrahydrofuran (THF), and organic peroxides. Manufactured in Germany under stringent ISO 9001-certified processes, the Dispensette® S Organic meets the mechanical robustness and dimensional stability requirements essential for GLP-compliant routine QC labs and synthetic chemistry workflows.
Key Features
- Digital volume display with large, high-contrast readout enabling rapid, error-resistant setting of volumes between 25 and 50 mL in 0.1 mL increments
- Tool-free, single-step calibration procedure—completed in under 5 seconds using standard gravimetric method per ISO 8655-3; traceable to NIST-traceable standards
- Ergonomic lever design reduces actuation force by >40% compared to conventional bottle top dispensers, minimizing operator fatigue during high-throughput dispensing
- Integrated air purge valve and solvent-resistant vent filter prevent backflow and protect internal mechanics from vapors and aerosols
- Autoclavable (121 °C, 20 min) dispensing tube and PFA tip support aseptic transfer protocols when used with sterile-filtered solvents
- Modular construction allows field replacement of seals, valves, and piston assemblies without specialized tools or service downtime
Sample Compatibility & Compliance
The Dispensette® S Organic 4630351 is validated for use with liquids exhibiting vapor pressures up to 600 mbar at operating temperatures between +15 °C and +40 °C. For liquids exceeding 300 mbar vapor pressure, slow aspiration is recommended to avoid cavitation and boiling-induced inaccuracies. It supports kinematic viscosities up to 500 mm²/s and densities up to 2.2 g/cm³—covering >95% of common organic synthesis and analytical reagents. The device complies with ISO 8655 (volumetric pipettes and dispensers), DIN EN ISO/IEC 17025 requirements for calibration traceability, and is compatible with FDA 21 CFR Part 11–enabled electronic lab notebooks (ELNs) when paired with optional data logging accessories. All wetted materials meet USP Class VI biocompatibility and EU REACH SVHC criteria.
Software & Data Management
While the 4630351 is a standalone mechanical instrument, its calibration records and usage logs integrate seamlessly into laboratory quality management systems (QMS). Each unit ships with a factory-issued calibration certificate referencing ISO/IEC 17025-accredited metrology. Users may document calibration events, maintenance intervals, and reagent-specific usage parameters in accordance with GLP Annex 11 and GMP Annex 11 requirements. Optional Bluetooth-enabled adapters (sold separately) support real-time volume tracking and audit trail generation for digital SOP compliance.
Applications
- Precise metering of anhydrous solvents in Schlenk-line and glovebox environments
- Controlled addition of concentrated acids during titration standardization or digestion protocols
- Reproducible dosing of peroxide-containing initiators in polymerization reactions
- High-integrity transfer of TFA in peptide synthesis workflows requiring low-metal contamination
- Routine preparation of calibration standards and QC reference solutions in environmental and pharmaceutical testing labs
- Dispensing of halogenated solvents in GC sample preparation where residual moisture must be avoided
FAQ
Can the Dispensette® S Organic 4630351 be used with hydrofluoric acid (HF)?
No. HF is incompatible with all wetted materials in this model and poses severe safety and corrosion risks. Use only HF-rated dispensers with Hastelloy C-276 or sapphire components.
Is sterilization by autoclaving supported?
Yes—the dispensing tube, tip, and PFA piston assembly are fully autoclavable at 121 °C for 20 minutes. The main body housing must not be autoclaved.
What is the recommended recalibration frequency?
Per ISO 8655-3 and internal lab SOPs, recalibration is advised before each new reagent batch, after any disassembly, and at minimum every 30 days for continuous-use environments.
Does the device require electrical power or batteries?
No. It operates entirely manually via ergonomic lever action—ideal for explosion-proof areas and glovebox integration.
How is traceability maintained for regulatory audits?
Each unit includes a unique serial number and calibration certificate with uncertainty values, measurement conditions, and technician signature—fully compliant with ISO/IEC 17025 and FDA 21 CFR Part 11 documentation expectations.
