CoMetro CP-M Series Constant Flow Pump

Overview

The CoMetro CP-M Series Constant Flow Pump is an engineered precision fluid delivery system designed for laboratory-scale applications requiring stable, pulse-free flow under high backpressure. Based on a dual-stage electronic compensation architecture—integrating a low-volume accumulator, non-contact pressure sensing, and closed-loop motor control—the CP-M series delivers consistent volumetric displacement across its operational range. Unlike peristaltic or syringe-based systems, the CP-M employs a positive-displacement piston mechanism with dynamically adjusted fill-and-discharge cycles, enabling true constant-flow behavior even during transient load changes. This architecture meets the stringent demands of analytical chemistry, catalytic reaction monitoring, microfluidic interfacing, and long-duration infusion protocols where flow stability directly impacts data integrity and reproducibility.

Key Features

• Ultra-low pulsation design achieved through integrated low-inner-volume accumulator and rapid-fill electronic compensation algorithm
• Non-contact pressure transduction system providing real-time feedback without diaphragm fatigue or fluid pathway contamination
• Dual-mode operation: local keypad control with intuitive parameter navigation and remote digital control via RS232 serial interface
• Configurable analog input support (0–5 V, 0–10 V, 4–20 mA) for synchronized operation within automated process workflows
• Built-in bypass valve and self-cleaning module to minimize carryover and extend service intervals between maintenance cycles
• Modular pump head suspension assembly enabling quick fluid path reconfiguration and alignment optimization
• Compliance-ready firmware architecture supporting audit trail logging and user-access level configuration (aligned with GLP/GMP documentation requirements)

Sample Compatibility & Compliance

The CP-M Series accommodates chemically aggressive solvents, aqueous buffers, and viscous reagents through optional fluid path configurations in either high-purity PEEK or electropolished 316 stainless steel—both certified for USP Class VI biocompatibility and ISO 10993-5 cytotoxicity testing. All wetted materials are compatible with common HPLC-grade solvents, including acetonitrile, methanol, THF, and concentrated acids/bases below pH 2 or above pH 12 (with appropriate material selection). The system conforms to IEC 61010-1 safety standards for laboratory equipment and supports traceable calibration protocols aligned with ISO/IEC 17025 requirements. Optional firmware modules enable 21 CFR Part 11-compliant electronic signatures and event-driven audit logging for regulated environments.

Software & Data Management

The CP-M Series supports native communication via RS232 using ASCII-based command protocol, enabling seamless integration into LabVIEW, Python-controlled automation frameworks, or custom SCADA environments. A dedicated PC utility provides real-time flow/pressure visualization, programmable ramp profiles, and exportable CSV logs timestamped to millisecond resolution. All configuration changes—including flow setpoints, pressure limits, alarm thresholds, and user permissions—are recorded with operator ID and timestamp. Firmware updates are performed via signed binary packages verified at boot time, ensuring system integrity and version traceability. Data export formats include UTF-8 encoded CSV and XML metadata bundles suitable for LIMS ingestion.

Applications

• High-pressure liquid delivery in preparative chromatography and supercritical fluid extraction systems
• Controlled reagent infusion for kinetic studies in homogeneous catalysis and enzyme kinetics assays
• Stable solvent delivery in microreactor platforms and continuous-flow synthesis setups
• Calibration standard delivery for mass flow meter validation and gravimetric flow verification
• Teaching laboratories requiring robust, serviceable instrumentation for fluid mechanics and process control curricula
• Pharmaceutical formulation development where precise volumetric dosing under variable backpressure is critical

FAQ

What flow rate ranges are available across the CP-M Series models?
The CP-M2xx subseries covers 0.001–5 mL/min (CP-M205), 0.01–10 mL/min (CP-M210), and 0.1–50 mL/min (CP-M250); the CP-M3xx series adds real-time pressure monitoring and configurable limit alarms while maintaining identical flow specifications.
Is the CP-M Series suitable for use with organic solvents and corrosive media?
Yes—when configured with 316 stainless steel fluid paths, the pump is rated for compatibility with common HPLC solvents, halogenated hydrocarbons, and dilute mineral acids/bases; PEEK configurations are recommended for strong oxidizers or high-pH applications.
Does the system support regulatory compliance for pharmaceutical R&D?
Firmware versions 2.4+ include optional 21 CFR Part 11 modules enabling electronic signatures, role-based access control, and immutable audit trails—validated for use in GxP-aligned method development and QC workflows.
How is flow accuracy verified and maintained over time?
Each unit ships with NIST-traceable calibration certificate; users may perform periodic verification using gravimetric or timed-volumetric methods per ASTM D3427 or ISO 5725 guidelines—the system retains calibration offsets in non-volatile memory.
Can multiple CP-M pumps be synchronized in a single workflow?
Yes—via external TTL trigger signals or master-slave RS232 daisy-chaining, enabling coordinated multi-pump gradients or sequential delivery sequences with sub-second timing resolution.