CZGY GY-CSB-WY Ultrasonic Water Bath Shaker

Overview

The CZGY GY-CSB-WY Ultrasonic Water Bath Shaker integrates precise temperature-controlled water bath functionality with synchronized mechanical oscillation and high-efficiency ultrasonic energy delivery. Engineered for reproducible sample processing in life science laboratories, it operates on the principle of combined thermal convection, orbital or reciprocating agitation, and cavitation-based acoustic energy transfer. This tri-modal platform enables uniform heat distribution, consistent mixing kinetics, and controlled sonication—critical for applications such as cell lysis, DNA shearing, nanoparticle dispersion, enzymatic reaction acceleration, and hybridization optimization. Unlike conventional shakers or standalone ultrasonic cleaners, the GY-CSB-WY maintains thermal stability while delivering calibrated acoustic power directly into aqueous media, minimizing thermal gradients and ensuring process repeatability across multiple experimental runs.

Key Features

• Brushless DC motor drive ensures constant speed output across the full 40–300 rpm range, with stable torque delivery and zero maintenance over extended operation cycles.
• Dual-mode oscillation: user-selectable reciprocating or rotary motion, optimized for differential suspension behavior of biological particulates and viscous reagents.
• 20 high-efficiency piezoelectric transducers distributed across the stainless-steel bath bottom ensure homogeneous ultrasonic field intensity; frequency selection (28 kHz standard, 40 kHz or 80 kHz optional) allows tuning for specific cavitation thresholds and shear profiles.
• Microprocessor-controlled PID temperature regulation with PT100 sensor feedback achieves ±0.5°C accuracy and ≤±0.5°C uniformity within the 5–100°C operating window (RT +5°C minimum).
• LCD interface supports multi-function programming: timed operation (0–9999 minutes/hours), auto-stop, power-failure memory, quick-start/stop, and motor stall protection.
• Full stainless-steel 304 construction of bath chamber and platform guarantees corrosion resistance, ease of decontamination, and compliance with GLP laboratory hygiene standards.
• Integrated safety architecture includes over-temperature alarm, current-limiting circuitry, and hardware-level motor lock detection.

Sample Compatibility & Compliance

The GY-CSB-WY accommodates standard laboratory vessels—including Erlenmeyer flasks (up to 2 L), centrifuge tubes (15–50 mL), microtiter plates, and custom immersion jigs—within its 40 × 31 cm platform. Its sealed water bath design prevents evaporation-induced concentration drift during long-duration incubations. The system meets structural and electrical safety requirements per IEC 61010-1:2010 for laboratory equipment. While not certified for medical device manufacturing, its temperature control fidelity, audit-trail-capable parameter logging (via optional RS232/USB data export), and programmable SOP execution support alignment with ISO/IEC 17025 method validation protocols and FDA 21 CFR Part 11–compatible workflows when integrated with validated LIMS platforms.

Software & Data Management

The embedded controller provides local parameter storage for up to 10 user-defined protocols, each including temperature setpoint, oscillation mode/speed/amplitude, ultrasonic power level, duration, and ramp profiles. Real-time monitoring of bath temperature, motor status, and ultrasonic output is visible on the LCD. Optional firmware upgrade enables serial communication (RS232 or USB) for remote command execution and time-stamped data logging (temperature, RPM, ultrasonic duty cycle) at 1-second intervals. Exported CSV files are compatible with common analytical tools (e.g., Python pandas, MATLAB, GraphPad Prism) for post-run statistical analysis and regulatory documentation.

Applications

• Cell disruption and organelle isolation via controlled cavitation without chemical lysis agents.
• Accelerated DNA fragmentation for next-generation sequencing library preparation.
• Homogenization of liposomal formulations, polymeric nanoparticles, and colloidal suspensions.
• Enhanced hybridization kinetics in Southern/Northern blotting and FISH protocols.
• Uniform dissolution testing of poorly soluble APIs under physiological temperature conditions.
• Enzyme activity assays requiring simultaneous thermal stabilization and substrate mixing.
• Environmental microbiology: extraction of extracellular polymeric substances (EPS) from biofilms.

FAQ

What ultrasonic frequencies are supported, and how do they affect sample processing?
The GY-CSB-WY ships with 28 kHz as default, optimized for general-purpose cavitation intensity and penetration depth. 40 kHz offers finer bubble collapse dynamics suited for sensitive biomolecules; 80 kHz (custom order) delivers higher-frequency, lower-energy cavitation ideal for nano-emulsification and gentle particle size reduction.
Can the instrument maintain temperature stability during high-power ultrasonic operation?
Yes—the 2000 W heating system dynamically compensates for ultrasonic energy dissipation, and the PID algorithm continuously adjusts heater duty cycle based on real-time PT100 readings, ensuring ≤±0.5°C deviation even at maximum 1200 W ultrasonic output.
Is the shaker compatible with sterile or anaerobic workflows?
The stainless-steel bath and sealed enclosure permit autoclave-compatible cleaning; however, the unit is not rated for Class II biosafety cabinet integration or inert-gas purging. For sterile applications, users should employ covered vessels and validate sterility post-processing.
Does the controller support GLP-compliant audit trails?
The base unit logs start/stop timestamps and final parameter states. Full electronic recordkeeping—including operator ID, parameter changes, and error events—requires optional software integration with a validated third-party LIMS or ELN system.
What is the maximum load capacity of the oscillating platform?
The platform supports up to 15 kg evenly distributed weight, sufficient for two 2-L flasks or four 500-mL bottles filled with aqueous media.