CZGY SHX-500 Biochemical Incubator

Overview

The CZGY SHX-500 Biochemical Incubator is a precision-engineered, forced-air convection incubator designed for stable, repeatable temperature control across a broad operational range of 5 °C to 60 °C. It employs a dual-mode thermoregulatory system—integrating resistive heating elements and a hermetically sealed compressor-based refrigeration unit—to achieve bidirectional temperature modulation without external chillers or cryogenic media. This architecture ensures consistent thermal performance under variable ambient conditions (10–30 °C), making it suitable for long-duration microbial growth studies, enzyme activity assays, cell culture pre-incubation, biochemical reaction kinetics, and environmental simulation protocols. The chamber’s uniform airflow path—optimized via internal baffle-guided circulation—minimizes vertical and horizontal thermal gradients, delivering ±1 °C spatial uniformity throughout the full 500 L working volume. Its structural design complies with IEC 61010-1 safety standards for laboratory equipment and incorporates fail-safe thermal cutoffs, door-open alarms, and overtemperature protection circuits.

Key Features

• Robust dual-wall construction: Cold-rolled steel exterior with electrostatic epoxy powder coating; mirror-polished 304 stainless-steel interior chamber resistant to corrosion from organic solvents and disinfectants.
• High-efficiency thermal insulation: 60 mm thick rockwool layer between inner and outer walls reduces heat transfer and improves energy efficiency during extended operation.
• Precision microprocessor control: Integrated PID algorithm with real-time compensation for load, door opening, and ambient drift; 0.1 °C resolution and ±0.5 °C accuracy verified per ISO 17025-accredited calibration procedures.
• Intuitive human-machine interface: Backlit 4.3-inch monochrome LCD display with tactile membrane keys; menu-driven navigation supports parameter setting, data logging history review, and alarm status diagnostics.
• Optimized air management: Horizontal laminar airflow pattern generated by a low-noise centrifugal fan (≤55 dB[A]) ensures rapid temperature recovery (<15 min from 25 °C to 37 °C after 30-second door opening) and uniform distribution across all shelf levels.
• Modular expandability: Pre-wired ports support optional accessories including humidity control (up to 95% RH, ±3% RH accuracy), UV-C germicidal irradiation (254 nm, 15 W), BOD-compatible power outlets, and analog/digital I/O for integration into centralized lab monitoring systems.

Sample Compatibility & Compliance

The SHX-500 accommodates standard microbiological vessels—including Petri dishes (up to 150 mm diameter), Erlenmeyer flasks (up to 2 L), multiwell plates, and serum bottles—on three independently adjustable stainless-steel shelves. Its chamber geometry (650 × 600 × 1300 mm) allows stacking of stacked plate racks or inverted flask holders without impeding airflow. The unit meets essential regulatory expectations for routine QC/QA workflows: temperature mapping validation reports are compatible with ASTM E2297-22 (Standard Guide for Validation of Thermal Processing Equipment), and firmware architecture supports basic electronic record integrity per FDA 21 CFR Part 11 when paired with optional audit-trail-enabled controllers. While not certified for GMP manufacturing environments out-of-the-box, the SHX-500 is routinely deployed in GLP-compliant research labs for stability testing (ICH Q1A–Q1E), environmental stress screening, and reference strain maintenance where traceable temperature documentation is required.

Software & Data Management

The base configuration includes local data logging of temperature setpoint, actual chamber temperature, and event timestamps (door open/close, alarm triggers) stored in non-volatile memory for up to 30 days at 1-minute intervals. Optional RS232 or RS485 serial interfaces enable connection to third-party SCADA platforms or custom Python/Matlab scripts for automated data export. With the upgraded color TFT touchscreen controller (CZGY-TC500), users gain access to trend graphing, multi-segment programmable ramp-soak profiles, password-protected user roles, and CSV-exportable logs with ISO 8601 timestamping. All firmware versions undergo periodic security patching and maintain backward compatibility with legacy calibration certificates issued under ISO/IEC 17025:2017 accredited calibration services.

Applications

• Bacterial and fungal cultivation: Escherichia coli, Bacillus subtilis, Saccharomyces cerevisiae, Aspergillus niger under defined aerobic conditions.
• Biochemical assay incubation: ELISA plate development, PCR pre-thermal cycling equilibration, Bradford/Lowry protein quantification, and substrate hydrolysis kinetics.
• Environmental simulation: Accelerated aging studies of pharmaceutical excipients, polymer degradation testing, and seed germination trials under controlled thermal regimes.
• Quality control workflows: Media sterility verification, antimicrobial susceptibility testing (AST), and endotoxin recovery validation per USP .
• Educational laboratories: Undergraduate microbiology courses, biotechnology training modules, and environmental science field station deployments.

FAQ

Does the SHX-500 support humidity control?
Humidity control is available as an optional add-on module (CZGY-HUM500), enabling operation from 30% to 95% RH with ±3% RH accuracy at 37 °C. It is not included in the base configuration.
Is UV sterilization integrated into this model?
UV-C germicidal lamps (254 nm) are standard on the MHP-series mold incubators but optional for the SHX-500. Installation requires dedicated mounting brackets and interlocked safety cutoffs.
Can the incubator be validated for ISO 17025-compliant temperature mapping?
Yes—the SHX-500’s mechanical and control architecture is fully compatible with IQ/OQ/PQ validation protocols. CZGY provides empty-chamber mapping templates and supports third-party qualification using calibrated thermistors or wireless data loggers.
What is the expected service life and maintenance interval?
Under normal laboratory use (8 h/day, 5 days/week), the compressor and fan assemblies are rated for ≥30,000 operating hours. Annual preventive maintenance—including refrigerant pressure check, condenser coil cleaning, and sensor calibration—is recommended.
Are spare parts and technical documentation available internationally?
All critical components (control board, compressor, fan motor, door gasket) are stocked globally through authorized CZGY distributors. Full English-language operation manuals, wiring schematics, and firmware update packages are provided upon request via secure download portal.