CZGY THZ-DL Desktop Full-Temperature Orbital Shaker

Overview

The CZGY THZ-DL Desktop Full-Temperature Orbital Shaker is an engineered platform for precise, reproducible incubation and agitation of biological and biochemical samples under controlled thermal conditions. Utilizing a robust air-bath heating system and a balanced orbital drive mechanism, the THZ-DL maintains uniform temperature distribution across the entire shaker platform while delivering consistent, low-shear mixing—critical for sensitive cell cultures, microbial growth studies, enzyme assays, and solubility testing. Its operating range spans from 5 °C (just above refrigerated ambient) to 60 °C, enabling applications from psychrophilic bacterial propagation to thermophilic protein expression protocols. The unit’s ±0.5 °C temperature control accuracy—verified via internal Pt100 sensor feedback and PID algorithm regulation—ensures compliance with method-defined thermal stability requirements in QC labs and academic research settings.

Key Features

• Orbital motion with 26 mm orbit diameter optimized for homogeneous suspension of suspension cultures, E. coli LB broth, mammalian cell lines, and immunoassay plates without splashing or foaming.
• Dual-mode timer: programmable from 1 minute to 9999 minutes (or hours), supporting unattended overnight runs and long-term kinetic experiments.
• Intuitive digital interface with real-time display of setpoint and actual values for both temperature and speed (40–300 rpm).
• Single-tier stainless steel platform (440 × 350 mm) fitted with corrosion-resistant spring clamps compatible with flasks (50–5000 mL), test tubes, microplates, and custom vessels.
• Integrated LED illumination enables visual monitoring without opening the chamber—minimizing thermal disturbance and contamination risk.
• Onboard UV-free sterilization cycle (via heated air circulation at ≥80 °C for configurable duration) supports routine decontamination between batches in shared core facilities.
• Modular mechanical architecture allows factory configuration for reciprocating motion upon request—facilitating protocol alignment with ASTM D2240 or ISO 1798 gelation kinetics standards where linear shear profiles are required.

Sample Compatibility & Compliance

The THZ-DL accommodates standard laboratory consumables including conical flasks (with foam or silicone stoppers), glass and polypropylene culture tubes, deep-well microplates, and custom bioreactor vials. Its air-bath design eliminates water contamination risks associated with water-jacketed systems—making it suitable for sterile microbiology workflows under ISO 14644-1 Class 7 cleanroom conditions. The unit meets electrical safety requirements per IEC 61010-1 and is designed to support instrument qualification (IQ/OQ/PQ) documentation in accordance with FDA 21 CFR Part 11 Annex 11 and EU GMP Annex 15. Temperature uniformity mapping (per ASTM E2234) and speed calibration traceability are supported via optional third-party certification packages.

Software & Data Management

While the THZ-DL operates as a standalone benchtop device with local parameter control, its analog/digital signal outputs (0–5 V or 4–20 mA) enable integration into centralized lab automation systems (e.g., LabVantage, STARLIMS). Optional RS-485 Modbus RTU communication module permits remote parameter setting, real-time data logging, and alarm event reporting—supporting 21 CFR Part 11 electronic record integrity through time-stamped audit trails and user-access-level permissions. All operational logs—including temperature deviation history, run completion status, and sterilization cycle validation—are exportable as CSV files for GLP archive retention.

Applications

• Microbial cultivation (E. coli, yeast, Bacillus spp.) in aerobic shake-flask bioprocessing.
• Cell-based assay development: suspension CHO or HEK293 transfection optimization, cytokine production kinetics.
• Biochemical reaction kinetics: ligand binding studies, antibody-antigen equilibration, enzymatic hydrolysis rate profiling.
• Environmental sample processing: soil leachate extraction, wastewater nutrient solubilization, heavy metal bioavailability testing.
• Pharmaceutical stability testing: excipient compatibility screening under accelerated agitation + temperature stress (ICH Q1A–Q5C aligned).
• Diagnostic reagent preparation: uniform mixing of conjugated nanoparticles, lateral flow assay buffer formulations.

FAQ

Can the THZ-DL be used for anaerobic culture applications?
Yes—when paired with gas-tight flask closures and external nitrogen/CO₂ gas manifolds, the unit supports microaerophilic and anaerobic growth protocols without modification.
Is the platform height adjustable?
No—the fixed-height design ensures mechanical stability and thermal consistency; however, optional platform risers (10/20 mm) are available for ergonomic alignment with biosafety cabinets or automated liquid handlers.
Does the sterilization function meet EN 17162:2020 requirements?
The built-in hot-air cycle achieves ≥80 °C chamber surface temperature for ≥30 min, satisfying the thermal decontamination performance criteria specified in EN 17162:2020 for non-invasive laboratory equipment.
What is the maximum load capacity per platform?
The rated dynamic load is 15 kg distributed evenly across the platform; exceeding this may affect speed stability and temperature homogeneity, particularly at ≥250 rpm.
Are calibration certificates included with shipment?
A factory-issued temperature and speed verification report (traceable to NIM China) is provided; full ISO/IEC 17025-accredited calibration is available as an add-on service.