Elite EClassical 3200 High-Performance Liquid Chromatograph
| Brand | Elite |
|---|---|
| Origin | Liaoning, China |
| Manufacturer Type | Direct Manufacturer |
| Instrument Type | Conventional HPLC System |
| Model | EClassical 3200 |
| Price Range | USD 14,000 – 56,000 (FOB) |
| Flow Rate Range | 0.001–10.000 mL/min |
| Maximum Operating Pressure | 130 MPa |
| Column Oven Temperature Control Range | 4–85 °C |
| UV-Vis Detector Wavelength Range | 190–800 nm |
Overview
The Elite EClassical 3200 is a fully integrated, high-performance liquid chromatography (HPLC) system engineered for precision, robustness, and regulatory compliance in routine and method-development laboratories. Built on classical reversed-phase, normal-phase, ion-exchange, and size-exclusion chromatographic principles, the system employs low-dead-volume binary or quaternary solvent delivery, high-stability column temperature control, and a dual-beam UV-Vis absorbance detector with real-time spectral acquisition. Designed to meet evolving global quality requirements—including ISO/IEC 17025, USP , and ICH Q2(R2) guidelines—the EClassical 3200 supports validated operation across pharmaceutical QC, environmental testing, food safety, and academic research applications. Its modular architecture enables seamless integration of autosamplers, fraction collectors, and optional mass spectrometry interfaces.
Key Features
- High-pressure binary or quaternary gradient pump delivering flow rates from 0.001 to 10.000 mL/min with ≤0.1% RSD precision and pulseless delivery across full pressure range (up to 130 MPa)
- Thermostatically controlled column compartment maintaining setpoint stability within ±0.2 °C over 4–85 °C, supporting method transfer and retention time reproducibility
- Dual-beam UV-Vis photodiode array detector with 190–800 nm wavelength coverage, 1 nm resolution, and real-time spectrum acquisition at up to 100 Hz sampling rate
- Integrated system controller with embedded Linux OS, supporting local operation without external PC dependency
- Modular design accommodating optional components: 120-position refrigerated autosampler (4–40 °C), preparative flow cell, conductivity detector for IC applications, and GLP-compliant audit trail module
- Front-panel touchscreen interface with intuitive workflow navigation, method template library, and password-protected user roles (Operator, Supervisor, Administrator)
Sample Compatibility & Compliance
The EClassical 3200 accommodates standard 2.1–4.6 mm ID analytical columns (including sub-2 µm particle packings) and supports mobile phases ranging from aqueous buffers to aggressive organic solvents (e.g., THF, DMSO). It complies with key international standards for analytical instrumentation: ASTM E2656 (HPLC system performance verification), ISO 17025:2017 (clause 6.4.3 for equipment validation), and EU GMP Annex 11 (data integrity requirements). All electronic records—including method files, chromatograms, calibration logs, and system suitability reports—support ALCOA+ principles (Attributable, Legible, Contemporaneous, Original, Accurate, Complete, Consistent, Enduring, Available) when configured with optional 21 CFR Part 11-compliant software modules.
Software & Data Management
The system operates with Elite ChromaLink 3.2 workstation software—a Windows-based platform supporting method development, sequence scheduling, peak integration, and report generation per GLP/GMP templates. ChromaLink includes built-in system suitability assessment (USP tailing factor, resolution, %RSD), electronic signature capability, and configurable audit trail with immutable timestamps. Raw data are stored in vendor-neutral .cdf format (compatible with OpenLab CDS, Chromeleon, and Empower via third-party converters). Optional cloud synchronization enables secure remote monitoring and multi-site data harmonization under ITAR- and GDPR-aligned infrastructure.
Applications
- Pharmaceutical QC: Assay, related substances, dissolution testing, and stability-indicating methods per ICH Q1–Q5
- Environmental analysis: PAHs, pesticides, and endocrine disruptors in water, soil, and biota extracts
- Food & beverage: Mycotoxins, preservatives, sweeteners, and vitamin profiling using AOAC and EN standards
- Academic research: Natural product isolation, polymer characterization (GPC/SEC), and chiral separations with polysaccharide-based columns
- Contract laboratories: Multi-client method validation, transfer, and routine batch release testing with full traceability
FAQ
Does the EClassical 3200 support method transfer between labs?
Yes—the system’s consistent dwell volume calibration, precise temperature control, and standardized detector response enable reliable inter-laboratory method transfer when documented per ICH Q5C and USP .
Is the UV-Vis detector compliant with pharmacopeial wavelength accuracy requirements?
Yes—wavelength accuracy is verified using holmium oxide and didymium filters per USP and EP 2.2.25, with factory-certified tolerance of ±1 nm across the 190–800 nm range.
Can the system be operated under 21 CFR Part 11 conditions?
Yes—when equipped with ChromaLink 3.2 + Audit Trail Module, it provides role-based access control, electronic signatures, and immutable audit logs meeting FDA requirements for regulated environments.
What column oven configurations are available?
Standard configuration includes a single-zone oven with forced-air circulation; optional dual-zone version supports independent pre-column and analytical column temperature control for advanced method development.
Is service and spare parts support available outside China?
Elite maintains authorized service partners in Southeast Asia, the Middle East, and Latin America; critical consumables (pump seals, lamp housings, flow cells) are stocked regionally and shipped globally under ISO 13485-certified logistics protocols.
