Erlab PCR Clean Bench Series
| Brand | Erlab |
|---|---|
| Origin | Jiangsu, China |
| Manufacturer Type | Authorized Distributor |
| Product Category | Domestic |
| Model Series | PCR Clean Bench |
| Pricing | Upon Request |
| Instrument Type | Horizontal Laminar Flow Clean Bench |
| Filtration | HEPA/ULPA U17 (99.999995% @ 0.12 µm) |
Overview
The Erlab PCR Clean Bench Series is a purpose-engineered horizontal laminar flow clean bench designed specifically for polymerase chain reaction (PCR), molecular biology, and other nucleic acid–sensitive applications where ultra-low particulate and biological contamination control are non-negotiable. Unlike standard vertical-flow biosafety cabinets, this system employs unidirectional horizontal airflow—generated by a low-turbulence, brushless DC motor-driven blower—passing through a certified ULPA U17 filter (efficiency ≥99.999995% at 0.12 µm particle size) to deliver ISO Class 3 (Class 10) clean air across the entire work surface. The airflow velocity is precisely maintained within the 0.3–0.5 m/s range per ISO 14644-1, ensuring consistent laminar integrity without turbulence-induced re-entrainment. A built-in 254 nm ultraviolet germicidal lamp provides validated surface decontamination between procedures, mitigating carryover risk in high-sensitivity amplification workflows. As a standalone unit requiring no ducting or external exhaust, it complies with EN 12464-1 (Lighting of Workplaces) and meets key functional requirements outlined in CLSI EP25-A and ISO/IEC 17025 for controlled environment validation.
Key Features
- ULPA U17 filtration (≥99.999995% efficiency at 0.12 µm), exceeding ISO 14644-1 Class 3 airborne particle limits
- Dual-mode operation: continuous laminar flow mode for active work; UV-only mode for post-procedure sterilization
- SmartStatus™ visual feedback system: dynamic LED light band (blue/green/red) combined with programmable audible alert patterns (e.g., 2 beeps = filter saturation warning; 4 beeps = UV lamp end-of-life)
- Optional activated carbon–impregnated molecular filter for adsorption of volatile organic compounds (VOCs), critical for preventing PCR inhibition from ambient lab contaminants such as ethanol, chloroform, or formaldehyde vapors
- Ergonomically contoured stainless steel work surface with seamless welds and 30° front sash angle to minimize operator fatigue and optimize airflow entry
- Integrated airflow monitoring sensor with real-time digital display (optional calibration traceable to NIST standards)
Sample Compatibility & Compliance
The Erlab PCR Clean Bench Series supports open-vessel manipulations of DNA/RNA templates, master mixes, primers, and enzymatic reagents without risk of aerosol-mediated cross-contamination. It is validated for use with common molecular techniques including qPCR, RT-PCR, NGS library prep, and CRISPR-Cas9 editing workflows. While not a biosafety cabinet (i.e., not suitable for handling viable pathogens), its design aligns with ISO 15189 Annex B.3 (requirements for pre-analytical molecular environments) and supports GLP-compliant documentation when paired with optional audit-trail-enabled software modules. All electrical components conform to IEC 61010-1 safety standards; UV lamp output is certified per IEC 62471 (Photobiological Safety of Lamps).
Software & Data Management
The embedded SmartStatus™ controller logs operational parameters—including total runtime, UV exposure cycles, filter usage hours, and airflow deviation events—for up to 12 months onboard. Data export is supported via USB-C interface in CSV format, enabling integration into LIMS or ELN systems. Optional firmware upgrade enables remote monitoring via Ethernet/Wi-Fi (IEEE 802.3/802.11ac), with TLS 1.2 encryption and role-based user access (administrator/operator). Audit trail functionality satisfies FDA 21 CFR Part 11 requirements for electronic records and signatures when configured with time-stamped, immutable event logging.
Applications
- PCR setup and master mix preparation in clinical diagnostics and research laboratories
- Cloning, plasmid purification, and transfection reagent handling
- Pre-sequencing sample preparation for Illumina and Oxford Nanopore platforms
- Forensic DNA extraction and low-template amplification workflows
- Cell culture media aliquoting where sterility—not biocontainment—is the primary objective
- Quality control testing of oligonucleotide synthesis batches
FAQ
Does this unit provide personnel protection?
No. The Erlab PCR Clean Bench is a horizontal laminar flow device intended solely for product protection. It does not protect the operator from hazardous biological or chemical agents.
What is the recommended filter replacement interval?
ULPA filters should be replaced every 18–24 months under typical usage (8 hrs/day, 5 days/week), or sooner if pressure drop exceeds 250 Pa as indicated by the SmartStatus™ display.
Can the molecular filter be installed retroactively?
Yes—retrofit kits are available for all models manufactured after Q3 2022, requiring only 30 minutes of technician time and no structural modification.
Is UV irradiance intensity validated per ISO 15858?
Yes. Each unit ships with a factory-issued UV validation certificate documenting 254 nm irradiance ≥100 µW/cm² at 1 cm distance from lamp surface, measured using NIST-traceable radiometry.
How is airflow uniformity verified during commissioning?
A certified third-party technician performs ISO 14644-3 Annex B.2-compliant anemometer mapping (minimum 36 points across work surface), with results documented in the Installation Qualification (IQ) report.
