EYELA N-1210BS-WB Rotary Evaporator

Overview

The EYELA N-1210BS-WB Rotary Evaporator is a high-performance, dual-mode (water/oil) heating bath rotary evaporator engineered for precise, reproducible solvent removal and compound concentration in research, quality control, and pilot-scale synthesis laboratories. Based on the fundamental principle of reduced-pressure distillation—where lowering the system pressure decreases the boiling point of solvents—the N-1210BS-WB enables gentle, efficient evaporation of thermally sensitive compounds across a broad volatility range. Its integrated electric lift mechanism, PTFE-sealed vacuum system, and dual-spiral inclined condenser collectively ensure high recovery yields, minimal bumping, and robust operational safety—particularly critical when handling flammable, corrosive, or low-volatility solvents under controlled thermal conditions.

Key Features

• Inclined dual-spiral condenser with 0.146 m² effective cooling area—optimized for high-efficiency condensation of vapors from low-boiling solvents (e.g., diethyl ether, dichloromethane) through mid- to high-boiling solvents (e.g., ethyl acetate, toluene, DMSO).
• Motor-driven vertical lift (110 mm stroke) with manual fine-adjustment extension (up to +130 mm), enabling seamless integration with explosion-proof glassware, large-capacity receiving flasks (up to 3 L), and confined-space installations such as fume hoods.
• PTFE-coated aluminum heating bath (5.4 L capacity) with precise digital temperature control (ambient to 180 °C; ±1.5 °C accuracy with water, ±3 °C with oil), supporting both aqueous and high-temperature oil-based evaporation protocols.
• Stepper motor-driven rotation (5–280 rpm) with digital speed display and smooth torque delivery—minimizing sample foaming and ensuring uniform film formation on flask surfaces.
• Automatic safety lift activation during power failure: the evaporating flask retracts fully upward to prevent prolonged thermal exposure and potential decomposition or charring of residue.
• Front-panel tactile controls for lift operation—designed for glove-compatible, low-opening fume hood use, reducing cross-contamination risk and maintaining containment integrity.
• Chemically resistant PTFE vacuum sealing gaskets—engineered for long-term stability under repeated vacuum cycling and exposure to aggressive organic solvents and acidic/basic vapors.

Sample Compatibility & Compliance

The N-1210BS-WB accommodates standard ground-glass jointed glassware including 1 L–3 L round-bottom flasks, 1 L receiving flasks, and optional BSF-series resin-film-coated condensers and flasks for enhanced corrosion resistance and optical clarity during real-time process monitoring. Its vacuum integrity (down to 10 hPa) and thermal stability support compliance with widely referenced laboratory standards, including ASTM E2041 (standard practice for rotary evaporation of organic extracts), ISO 6425 (laboratory equipment—general requirements), and internal GLP/GMP documentation workflows. When paired with the optional NVC-3000 vacuum controller (via RS-232 or analog signal interface), the system supports programmable vacuum ramping, audit-trail logging, and synchronized control of external chillers, vacuum pumps, and heating baths—facilitating 21 CFR Part 11–compliant data capture when integrated into validated environments.

Software & Data Management

While the N-1210BS-WB operates as a standalone instrument with local digital controls, its compatibility with the NVC-3000 Vacuum Controller enables advanced process automation. The NVC-3000 provides real-time vacuum profiling, event-triggered parameter adjustments (e.g., reduce vacuum upon reaching target temperature), and timestamped operational logs exportable as CSV files. These logs include bath temperature setpoint/actual, rotation speed, vacuum level, lift position status, and system error codes—supporting traceability requirements in regulated pharmaceutical, agrochemical, and contract research settings. No proprietary software installation is required; configuration and monitoring occur via intuitive front-panel navigation or optional PC-based terminal emulation.

Applications

• Concentration of natural product extracts (e.g., plant alkaloids, essential oils) without thermal degradation.
• Removal of reaction solvents following Grignard, Suzuki, or esterification reactions—especially where residual solvent limits must meet ICH Q3C thresholds.
• Preparative-scale purification in synthetic organic chemistry labs requiring repeatable, scalable evaporation parameters.
• Lyophilization pre-concentration steps prior to freeze-drying of protein formulations or nanoparticle suspensions.
• Environmental analysis workflows involving EPA Method 3510C (separation of extractable petroleum hydrocarbons) and similar solvent-extraction protocols.
• QC release testing of raw materials and intermediates where batch-to-batch consistency in drying efficiency is critical.

FAQ

What is the maximum recommended operating temperature for the heating bath when using oil versus water?
The bath achieves ±1.5 °C accuracy up to 180 °C with silicone or mineral oil; water-based operation is limited to ≤100 °C with comparable precision.
Can the N-1210BS-WB be integrated into an automated lab platform?
Yes—via NVC-3000 controller interface, it supports RS-232 communication and analog I/O for coordination with LIMS, PLCs, or robotic liquid handlers.
Is the PTFE vacuum seal compatible with halogenated solvents such as chloroform or carbon tetrachloride?
Yes—the fluoropolymer formulation resists swelling and creep under continuous exposure to Class I and II organic solvents per ASTM D471 guidelines.
Does the unit include a vacuum pump or cooling circulator?
No—these are external accessories; the system features standardized 10 mm OD vacuum and coolant ports for seamless connection to third-party equipment.
What safety certifications does the N-1210BS-WB carry for international deployment?
It complies with IEC 61010-1 (Safety Requirements for Electrical Equipment for Measurement, Control, and Laboratory Use) and bears CE marking for the European Economic Area; UL/cUL listing is available upon request for North American installations.