EZONE CHEMIST Coiled Tube Reactor
| Brand | EZONE CHEMIST |
|---|---|
| Origin | Guangdong, China |
| Manufacturer Type | Authorized Distributor |
| Country of Origin | China |
| Model | Custom Configurable |
| Pricing | Available Upon Request |
| Inner Diameter | 0.8 mm / 2 mm |
| Length Options | 1.25 m, 1.6 m, 2.5 m, 3.2 m, 3.8 m, 18 m |
| Volume Range | 0.65 mL – 70 mL |
| Temperature Range | −20 °C to 200 °C |
| Pressure Rating | 0–100 bar |
Overview
The EZONE CHEMIST Coiled Tube Reactor is a modular, precision-engineered continuous-flow reaction platform designed for laboratory-scale process development, kinetic studies, and catalyst screening under controlled thermal and pressure conditions. Built upon the fundamental principles of plug-flow reactor (PFR) hydrodynamics, it leverages tightly wound tubing geometry to deliver consistent residence time distribution, enhanced heat transfer coefficients, and minimized axial dispersion—critical attributes for reproducible heterogeneous and homogeneous reactions. Its compact coiled architecture enables rapid thermal equilibration and uniform temperature profiles along the entire reaction path, making it particularly suitable for exothermic or thermally sensitive transformations where precise thermal management is non-negotiable.
Key Features
- Modular configuration with standardized Swagelok®-compatible fittings (e.g., 1/4″ VCR, 1/8″ NPT, SS 316L compression), enabling rapid integration into existing flow chemistry setups without custom machining.
- Multiple tubing material options—including stainless steel 316L, Hastelloy C-276, and fluoropolymer-lined variants—to ensure chemical compatibility across aggressive reagents (e.g., strong acids, halogenated solvents, organometallics) and elevated temperatures.
- Precision-mandrel coiling ensures consistent curvature radius and eliminates kinking, preserving laminar flow integrity and minimizing pressure drop anomalies across all length and diameter combinations.
- Pressure-rated construction certified to 100 bar at 200 °C, with traceable ASME B31.3-compliant documentation available upon request for regulated environments.
- Thermally insulated jacketing interfaces support integration with external circulators or heating mantles; optional integrated Pt100 RTD ports allow real-time in-line temperature monitoring at inlet, mid-coil, and outlet positions.
Sample Compatibility & Compliance
The reactor accommodates liquid, gas-liquid, and slurry-phase chemistries—including catalytic hydrogenations, photochemical oxidations, nitration, and enzymatic biotransformations—across a broad physicochemical spectrum. Its inert wetted surfaces and low dead-volume design minimize adsorption and carryover, supporting sequential multi-step reactions in telescoped flow sequences. The system conforms to ISO 9001-certified manufacturing practices and supports GLP/GMP-aligned workflows through traceable lot documentation for all tubing batches. While not inherently FDA 21 CFR Part 11-compliant (as a hardware-only component), it integrates seamlessly with validated control systems that provide electronic audit trails, user access controls, and data integrity safeguards required for regulated pharmaceutical development.
Software & Data Management
As a hardware module, the Coiled Tube Reactor operates independently of proprietary software but is fully interoperable with industry-standard flow control platforms—including Syrris Asia, Vapourtec R-Series, and Chemtrix Labtrix controllers—via analog 0–10 V or digital RS485/Modbus RTU interfaces. All dimensional and thermal specifications are programmatically accessible via manufacturer-provided datasheets and CAD models (STEP, IGES), facilitating digital twin implementation in AspenTech or COMSOL Multiphysics for residence time distribution modeling and thermal stress simulation. Calibration certificates for pressure transducers and temperature sensors used in conjunction with the reactor are issued per ISO/IEC 17025-accredited laboratories when bundled with measurement instrumentation.
Applications
- Kinetic parameter estimation for reaction mechanisms using residence time variation and in-line FTIR/UV-Vis spectroscopy.
- High-temperature, high-pressure catalysis screening (e.g., Fischer–Tropsch, CO₂ hydrogenation) with catalyst immobilization on tube walls or packed-bed inserts.
- Photochemical synthesis under UV/visible irradiation using quartz-coiled variants (optional).
- Process intensification studies comparing batch vs. continuous performance metrics (space-time yield, selectivity, E-factor).
- Safe handling of energetic intermediates (e.g., diazonium salts, azides) via small internal volume and immediate quench capability downstream.
FAQ
What tubing materials are available for corrosion-resistant applications?
Stainless steel 316L (standard), Hastelloy C-276 (for HF/HCl service), and PFA- or PTFE-lined stainless steel for ultra-high purity or strongly oxidizing media.
Can the reactor be used for gas-phase reactions?
Yes—when paired with mass flow controllers and back-pressure regulators, it supports steady-state gas-phase pyrolysis, cracking, and heterogeneous catalysis up to 100 bar.
Is validation support provided for GxP environments?
While the reactor itself is not a “qualified instrument,” EZONE CHEMIST supplies URS templates, FAT/SAT protocols, and material traceability dossiers to accelerate IQ/OQ execution by end users.
How is residence time calculated and verified?
Residence time τ is derived from geometric volume and volumetric flow rate (τ = V/Φ); experimental verification is performed using step-change tracer studies with conductivity or UV-active markers.
Do you offer custom coil geometries beyond standard lengths?
Yes—custom mandrel winding, multi-zone thermal zoning, and integrated micro-mixer inlets are available under engineering consultation and NRE agreement.
