GE Sievers 900 Laboratory Total Organic Carbon (TOC) Analyzer – Refurbished Unit

Overview

The GE Sievers 900 Laboratory Total Organic Carbon (TOC) Analyzer is a rigorously refurbished, performance-validated benchtop instrument engineered for high-precision, regulatory-compliant TOC quantification in pharmaceutical, biotechnology, and environmental laboratories. It employs a dual-stage oxidation principle—ultraviolet (UV) radiation combined with sodium persulfate—to fully mineralize non-purgeable organic carbon (NPOC) into CO₂, followed by highly selective detection via Sievers’ proprietary membrane conductivity technology. This method ensures minimal interferences from inorganic ions, chloride, or conductivity drift, delivering trace-level sensitivity (detection limit: 0.03 ppb C) and long-term measurement stability across the full dynamic range of 0.03 ppb to 50 ppm. Unlike combustion-based TOC analyzers, the UV/persulfate approach eliminates the need for high-temperature ovens, carrier gases, or catalyst regeneration—significantly reducing operational complexity and maintenance overhead. The instrument’s compact footprint (19.2 cm wide) supports space-constrained QC labs without compromising analytical robustness.

Key Features

• Automated calibration and system suitability verification per USP and EP 2.2.44 protocols—including daily zero/span checks, oxidation efficiency validation, and conductivity cell diagnostics
• Intelligent reagent management: Onboard reagent calculation and dosing algorithm dynamically adjusts persulfate concentration and UV exposure time based on sample conductivity and expected TOC load—enabling unattended operation for up to 24 hours
• 12-month calibration stability verified under ISO/IEC 17025-accredited conditions; reduces frequency of recalibration and associated documentation burden
• Full-color 7-inch capacitive touchscreen interface with intuitive workflow navigation, password-protected user roles (Operator, Supervisor, Administrator), and real-time method status monitoring
• Integrated hardware architecture with sealed optical path, temperature-stabilized conductivity cell, and redundant pressure sensors to ensure signal integrity during extended batch runs
• No external gas supply, compressed air, or auxiliary oxidant sources required—operational readiness achieved with only deionized water and standard laboratory power (100–240 VAC)

Sample Compatibility & Compliance

The Sievers 900 is validated for aqueous matrices including purified water (PW), water for injection (WFI), clean-in-place (CIP) rinse solutions, buffer formulations, and environmental surface rinse samples. Its NPOC methodology meets pharmacopeial requirements for compendial water testing (USP , EP 2.2.44, ChP 0831, JP, IP) and environmental compliance (USEPA Methods 415.3 and 9060A). All refurbished units undergo full functional verification per ASTM D5907 and are accompanied by a Certificate of Reconditioning that documents as-received condition, component-level refurbishment history (including replacement of UV lamp, membrane conductivity cell, and fluidic manifolds), and post-refurbishment performance data against certified TOC standards (e.g., potassium hydrogen phthalate, sucrose). Units are pre-configured for GLP/GMP environments with configurable audit trail logging, electronic signature support, and 21 CFR Part 11–compliant software architecture.

Software & Data Management

The embedded Sievers Insight™ software provides comprehensive data acquisition, processing, and reporting capabilities. Raw conductivity signals are processed using adaptive baseline correction and second-derivative peak integration algorithms to resolve overlapping CO₂ transients. Reports are generated in PDF and CSV formats with embedded metadata—including instrument ID, operator ID, calibration dates, system suitability results, and raw chromatograms. Audit trails record all critical events (method edits, calibration actions, user logins, data exports) with immutable timestamps and user attribution. Data archives are stored locally on encrypted internal flash memory (16 GB) and support scheduled backups to network drives via Ethernet or USB. Optional LIMS integration is available through ASTM E1384-compliant HL7 or CSV export protocols.

Applications

• Pharmaceutical water system monitoring (PW, WFI, pure steam condensate)
• Cleanliness verification of manufacturing equipment and piping systems
• Validation of depyrogenation tunnels and autoclaves via rinse water analysis
• Environmental wastewater discharge compliance testing
• Bioprocess intermediate and final product release testing
• Method transfer and comparability studies between legacy Sievers 800 and current-generation platforms

FAQ

Is this unit covered by original GE factory warranty?
No—this is a professionally refurbished unit supplied with a 6-month limited warranty covering parts and labor for defects in materials or workmanship.
Has the UV lamp been replaced during refurbishment?
Yes—every unit receives a new OEM GE UV lamp (part # 1000-0127) with documented installation date and initial intensity calibration.
Can the instrument be integrated into an existing LIMS?
Yes—via configurable CSV export, HL7 messaging, or optional OPC-UA server add-on (sold separately).
What documentation accompanies the instrument?
Certificate of Reconditioning, As-Tested Performance Report (including linearity, LOD/LOQ, precision at 50 ppb and 5 ppm), IQ/OQ checklist, and electronic copy of user manuals and software license.
Is preventive maintenance included in the purchase price?
No—but annual PM kits (including replacement membranes, tubing, and reagents) and certified technician support are available upon request.