GN-300 Nitrogen Generator by Zhongxing Huili

Overview

The GN-300 Nitrogen Generator is a compact, membrane-based nitrogen generation system engineered for reliable, on-demand supply of high-purity nitrogen gas in analytical laboratories and quality control environments. It employs a pressure swing adsorption (PSA) process—optimized with advanced carbon molecular sieve (CMS) technology—to separate nitrogen from compressed ambient air. Unlike electrolytic or cryogenic systems, the GN-300 operates without liquid nitrogen, hazardous chemicals, or high-voltage electrolysis cells, delivering consistent 99.995% nitrogen purity (O₂ residual ≤5 ppm) across its full flow range of 0–300 mL/min. Designed for integration with GC, LC-MS, FTIR, and sample preparation stations, it eliminates cylinder dependency, reduces operational risk, and supports continuous unattended operation under regulated laboratory conditions.

Key Features

• Stable nitrogen output at ≥99.995% purity (verified per ISO 8573-1:2010 Class 2 compressed air quality input)
• Digitally controlled flow regulation with real-time LED display and automatic flow tracking—maintains setpoint accuracy within ±2% of full scale
• Integrated pressure regulation with adjustable output range of 0–0.4 MPa (0–4 bar), compatible with standard GC carrier gas inlets and purge lines
• Compact footprint (320 × 180 × 350 mm) and lightweight design (10 kg net weight) for benchtop deployment in space-constrained labs
• Low-power architecture (≤150 W max) with thermal overload protection and auto-shutdown on pressure loss or filter saturation
• Pre-installed particulate and coalescing filters upstream of CMS bed; service interval recommended every 6,000 operating hours or per ISO 8573 maintenance guidelines

Sample Compatibility & Compliance

The GN-300 is intended for use with clean, oil-free, desiccated compressed air feed (dew point ≤ −40 °C, particle size ≤0.01 µm, oil aerosol ≤0.01 mg/m³). It complies with general safety requirements outlined in IEC 61010-1 for laboratory electrical equipment. While not certified to FDA 21 CFR Part 11 out-of-the-box, its stable output and traceable performance parameters support GxP-aligned validation protocols—including IQ/OQ documentation templates available upon request. The unit meets electromagnetic compatibility (EMC) standards per EN 61326-1 and is suitable for installation in ISO/IEC 17025-accredited testing laboratories where instrument gas sourcing must be documented and auditable.

Software & Data Management

The GN-300 operates as a standalone hardware system with no embedded firmware or remote connectivity. All operational parameters—including flow rate, output pressure, and runtime—are displayed via a 3-digit LED interface. For laboratories requiring data capture, analog 0–5 V or 4–20 mA output signals (optional accessory) can be interfaced with LabVIEW, DeltaV, or SCADA systems for trend logging and alarm integration. Audit-ready records may be generated manually or via external data loggers synchronized to the generator’s status indicators—supporting GLP/GMP traceability when paired with defined SOPs for preventive maintenance and purity verification (e.g., periodic O₂ sensor calibration using certified reference gas).

Applications

• Carrier gas supply for capillary gas chromatography (GC) and GC-MS systems requiring ultra-high-purity nitrogen
• Purge and trap sample introduction, headspace analysis, and thermal desorption instrumentation
• Inert blanketing during solvent evaporation, lyophilization, and reactive sample handling
• Nitrogen sparging in UV-Vis spectrophotometry and elemental analysis workflows
• Gas supply for FTIR gas cells, laser cavity purging, and plasma cleaning pre-treatment stages
• Backup or primary nitrogen source in pharmaceutical QC labs compliant with USP and EP 2.2.47 specifications

FAQ

What compressed air specifications are required for optimal GN-300 performance?
Ambient air must be supplied via an oil-free compressor with integrated refrigerated dryer and dual-stage filtration (coalescing + activated carbon) meeting ISO 8573-1:2010 Class 2. Inlet dew point shall not exceed −40 °C, and total hydrocarbon content must remain below 0.1 mg/m³.
Can the GN-300 replace liquid nitrogen in cryogenic applications?
No. The GN-300 delivers gaseous nitrogen at ambient temperature and is not designed for cryogenic cooling. It is strictly intended for inerting, carrier, and purge applications requiring gaseous N₂ at flow rates up to 300 mL/min.
How often does the carbon molecular sieve require replacement?
Under nominal operating conditions and with proper inlet air conditioning, the CMS column is rated for ≥20,000 hours of service life. Replacement is indicated only when nitrogen purity falls below 99.99% (O₂ >10 ppm) during routine verification using a calibrated electrochemical O₂ analyzer.
Is the GN-300 compatible with Agilent, Thermo Fisher, and Shimadzu GC systems?
Yes—its pressure-regulated output (0–0.4 MPa) and stable flow profile meet manufacturer-specified carrier gas requirements for all major GC platforms. A standard 1/8″ stainless steel tubing connection and SAE J1962-compliant fitting kit are included.
Does the unit include a built-in oxygen monitor?
No. Real-time O₂ monitoring requires an optional external electrochemical sensor (e.g., Teledyne Advanced Pollution Instrumentation model 3000 series), which can be plumbed in-line downstream for continuous purity verification.