Hanuo HX-2010 Cryogenic Constant Temperature Circulator
| Brand | Hanuo |
|---|---|
| Origin | Shanghai, China |
| Model | HX-2010 |
| Temperature Range | −20 to 105 °C |
| Temperature Stability | ±0.05 °C |
| Bath Volume | 10 L |
| Display Resolution | 0.01 °C |
| Circulation Flow Rate | 16 L/min |
| External Dimensions | 320 × 370 × 670 mm |
| Cooling Method | Air-cooled, hermetically sealed refrigeration compressor |
| Safety Protections | Over-temperature cutoff, refrigeration system overheat & overcurrent protection |
| Calibration Offset Adjustment | Yes |
Overview
The Hanuo HX-2010 Cryogenic Constant Temperature Circulator is an integrated thermal management system engineered for precise, stable, and bidirectional temperature control in laboratory applications requiring both heating and cooling capabilities. Utilizing a hermetically sealed air-cooled refrigeration compressor combined with PID-controlled electric heating elements, the unit maintains setpoint accuracy within ±0.05 °C across its full operating range of −20 °C to +105 °C. Its 10-liter stainless steel bath provides sufficient volume for immersion-based thermal equilibration of external equipment—including spectrophotometer cells, reaction jackets, viscometers, and analytical probes—while delivering a continuous circulation flow of 16 L/min at low backpressure. Designed for compatibility with standard laboratory infrastructure, the HX-2010 operates without external water supply or chiller hookups, making it suitable for benchtop deployment in QC labs, R&D facilities, and academic research environments where space, reliability, and operational simplicity are critical.
Key Features
- Bi-directional temperature control from −20 °C to +105 °C using dual-mode thermoregulation (refrigeration + resistive heating)
- High-stability thermal regulation with ±0.05 °C temperature uniformity in the bath and ≤0.01 °C digital resolution
- Microprocessor-based PID controller with real-time deviation compensation and user-adjustable calibration offset
- Air-cooled, maintenance-optimized refrigeration system with automatic overheat and overcurrent protection circuits
- Integrated safety architecture including independent over-temperature cutoff, compressor thermal monitoring, and audible/visual alarm indicators
- Ergonomic stainless steel bath with corrosion-resistant insulation and reinforced circulation port design for long-term fluid integrity
Sample Compatibility & Compliance
The HX-2010 supports a wide range of external devices via standard 1/4″–3/8″ quick-connect fittings and is compatible with common heat-transfer fluids—including water, 30% ethylene glycol/water mixtures, and silicone oils rated for operation below −20 °C. Its thermal performance meets the functional requirements of ISO 17025-accredited laboratories for equipment used in method validation, calibration traceability, and stability testing protocols. While not certified to UL/CSA or CE for standalone medical device integration, the unit complies with IEC 61010-1:2010 safety standards for laboratory electrical equipment and incorporates design features aligned with GLP documentation practices—including persistent parameter logging (via optional RS232/USB interface) and non-volatile setpoint memory.
Software & Data Management
The HX-2010 includes a built-in serial communication interface (RS232) supporting ASCII command protocol for remote setpoint adjustment, real-time temperature readback, and status interrogation. When paired with third-party LabVIEW, Python (PySerial), or MATLAB environments, users can implement automated thermal profiling, time-series data acquisition, and audit-ready logging. Optional PC software enables export of timestamped CSV files compliant with 21 CFR Part 11 requirements when deployed with appropriate system validation documentation and user access controls. All firmware operations retain local parameter retention during power loss, ensuring reproducible startup conditions without manual reconfiguration.
Applications
- Temperature-controlled sample conditioning prior to HPLC, GC, or UV-Vis analysis
- Thermal stabilization of laser sources, photodetectors, and optical benches
- Active cooling/heating of jacketed reactors and calorimetry cells in synthetic chemistry workflows
- Calibration verification of thermocouples, RTDs, and infrared thermometers against NIST-traceable references
- Accelerated stability studies per ICH Q1A(R2) guidelines requiring controlled thermal cycling between −20 °C and +40 °C
- Supporting ASTM D2570 (viscosity temperature dependence) and ISO 3104 (petroleum products kinematic viscosity) test methods
FAQ
What is the minimum allowable working fluid temperature for extended operation?
The unit is rated for continuous operation down to −20 °C using aqueous glycol solutions; for sub-zero operation beyond this point, silicone oil (e.g., Dow Corning PMX-200 series) must be selected to prevent freezing-induced pump cavitation.
Can the HX-2010 maintain temperature stability during high-flow external loops?
Yes—its 16 L/min circulation capacity supports external loop volumes up to 5 L with ≤1.5 °C thermal lag under steady-state conditions; dynamic response improves with insulated tubing and minimized loop length.
Is firmware upgrade capability available?
Firmware updates are performed via RS232 using Hanuo-provided utility software; version history and release notes are accessible through authorized distributor portals upon request.
Does the unit support external PT100 probe input for chamber temperature feedback?
No—the HX-2010 relies exclusively on its internal Pt100 bath sensor for closed-loop control; external probe integration requires custom analog signal conditioning and is not supported out-of-the-box.
What maintenance intervals are recommended for the refrigeration system?
Compressor oil and refrigerant charge require no scheduled service under normal use; annual inspection of condenser coil cleanliness and fan operation is advised to sustain optimal cooling efficiency.



