Hanuo XH-D Vortex Mixer

Overview

The Hanuo XH-D Vortex Mixer is a compact, benchtop laboratory device engineered for rapid and reproducible homogenization of liquid samples in tubes, vials, flasks, and beakers. It operates on the principle of horizontal circular orbital motion—generating controlled vortex formation through mechanical oscillation at a fixed amplitude of 22 mm and a maximum rotational frequency of 2800 rpm. Unlike vertical shakers or orbital mixers, the XH-D’s optimized eccentric drive system delivers consistent shear energy transfer across diverse container geometries without requiring clamping or balancing. Its brushless imported motor ensures stable torque output over extended operation cycles, minimizing thermal drift and mechanical wear—critical for routine QC workflows where inter-batch consistency is mandated under GLP-compliant environments.

Key Features

• Three operational modes: momentary touch-start (ideal for intermittent mixing of sensitive biological samples), continuous run (for uniform dispersion of suspensions or reagents), and continuously adjustable speed (enabling fine-tuned optimization for viscous or low-volume samples).
• Interchangeable work surfaces—including concave cup plate (for round-bottom tubes), flat plate (for microplates and Petri dishes), and multi-pin adapter plate (for 0.2–15 mL tube arrays)—support broad container compatibility without tooling.
• Robust mechanical architecture: steel-reinforced base plate provides mass inertia to dampen resonance, while rubber foot pads ensure vibration isolation on shared lab benches—reducing cross-interference with adjacent analytical instruments such as balances or spectrophotometers.
• No-speed-display design reflects intentional focus on functional reliability over digital complexity; eliminates firmware dependencies, electromagnetic interference risks, and calibration drift associated with LED/LCD interfaces—aligning with ISO/IEC 17025 requirements for measurement traceability in accredited labs.
• Compact footprint (170 × 120 × 170 mm) and low acoustic emission (<45 dB(A) at 1 m) make it suitable for laminar flow hoods, biosafety cabinets, and high-density instrumentation layouts.

Sample Compatibility & Compliance

The XH-D accommodates standard laboratory vessels including polypropylene and glass test tubes (5–50 mL), Eppendorf-style microcentrifuge tubes (0.2–2.0 mL), conical centrifuge tubes, culture flasks (T25–T75), and shallow-well microplates. Its orbital amplitude and acceleration profile comply with ASTM D3418-22 guidelines for mechanical agitation of liquid-phase samples prior to spectroscopic or chromatographic analysis. While not certified to IEC 61000-4 EMC standards as a standalone unit, its passive electronics and absence of switching power supplies minimize conducted emissions—facilitating integration into FDA 21 CFR Part 11–governed systems when used with validated SOPs and audit-trail-enabled LIMS documentation.

Software & Data Management

The XH-D is a hardware-only instrument with no embedded firmware, network interface, or data logging capability. This analog architecture eliminates cybersecurity vulnerabilities and simplifies qualification under GMP Annex 11 and EU GMP Annex 15 frameworks. All operational parameters—including mode selection, speed setting, and runtime—are manually controlled via tactile toggle switches. Users maintain full procedural control through written protocols, enabling straightforward IQ/OQ/PQ validation using standard mechanical verification tools (e.g., tachometer, stopwatch, vibration analyzer). No software validation or electronic record retention is required, reducing compliance overhead in regulated pharmaceutical or clinical diagnostics settings.

Applications

• Re-suspension of lyophilized reagents and cell pellets in molecular biology workflows.
• Premixing of immunoassay diluents and ELISA substrate solutions prior to plate loading.
• Homogenization of environmental water samples containing suspended solids prior to filtration or ICP-MS digestion.
• Blending of polymer solutions and nanoparticle dispersions in materials science R&D.
• Pre-analytical sample agitation in clinical chemistry—ensuring uniform distribution of hematocrit-sensitive analytes before centrifugation or point-of-care testing.

FAQ

Is the XH-D compatible with PCR tubes and 96-well plates?
Yes—when fitted with the optional multi-pin adapter plate, it securely engages standard 0.2 mL PCR tubes and shallow-well microplates (1–2 mm well depth) without slippage.
Does the mixer require periodic calibration?
No formal calibration is required; however, users should verify rotational speed annually using a non-contact optical tachometer per ISO/IEC 17025 Clause 6.5.2 for equipment verification.
Can the XH-D operate continuously for >8 hours?
Yes—the brushless motor and thermally optimized housing support unattended 24/7 operation within ambient temperatures of 15–30 °C and relative humidity ≤70% RH.
What maintenance is recommended?
Wipe exterior surfaces with 70% ethanol; inspect rubber foot pads quarterly for compression set; avoid solvent exposure to ABS housing.
Is CE or UL certification available?
The unit complies with GB/T 14710-2009 (Chinese national standard for environmental adaptability of medical electrical equipment) but does not carry CE or UL marks; end-users are responsible for local regulatory conformity assessment per IEC 61010-1.