KRSYQ KRS-DS21-6 Digital Display Constant Temperature Water Bath, Dual-Row 6-Well

Overview

The KRSYQ KRS-DS21-6 Digital Display Constant Temperature Water Bath is a precision-engineered laboratory thermal platform designed for stable, uniform, and repeatable temperature control in aqueous environments. Operating on the principle of conduction-based heat transfer via a thermostatically regulated water medium, it delivers consistent thermal energy across all six wells—arranged in a dual-row configuration—to ensure minimal inter-well temperature deviation (< ±0.2 °C at setpoint). Its integral stainless steel bath chamber eliminates weld seams, reducing corrosion pathways and enhancing long-term structural integrity under continuous operation. The unit is engineered for routine use in controlled laboratory workflows requiring ISO/IEC 17025-aligned thermal stability, including sample equilibration prior to analytical testing, enzymatic reaction incubation, dissolution testing per USP <711>, and reagent pre-warming in clinical chemistry protocols.

Key Features

• Digital PID temperature controller with real-time LED display, enabling setpoint entry and dynamic feedback adjustment within 0.1 °C resolution
• Integrated over-temperature cut-off circuitry that halts heating when internal sensor readings exceed user-defined limits by >2 °C, complying with IEC 61010-1 Class II safety requirements
• Ground-fault circuit interrupter (GFCI)-compatible electrical design with reinforced insulation and double-pole switching for personnel protection against leakage currents
• Modular well plate layout: two parallel rows of three 65-mm-diameter wells (standard Ø65 mm compatibility with common glassware including 50 mL–500 mL beakers and test tubes)
• Seamless one-piece 304 stainless steel bath tank with electropolished interior surface, minimizing biofilm adhesion and facilitating GLP-compliant cleaning validation
• High-efficiency 1500 W immersion heater with low thermal inertia, achieving <15 min ramp time from ambient to 90 °C at full load (16 L water)

Sample Compatibility & Compliance

The KRS-DS21-6 accommodates standard laboratory vessels without adapter requirements: round-bottom flasks (up to 500 mL), graduated cylinders, culture tubes, and capped vials fit securely within its recessed wells. Its operating range (ambient to 99 °C) supports ASTM D129-18 (petroleum product evaporation), ISO 8587:2021 (sensory analysis sample conditioning), and pharmacopeial water bath applications such as USP <721> (melting point determination) and EP 2.2.17 (microbiological assay incubation). The device meets CE marking requirements for electromagnetic compatibility (EN 61326-1) and low-voltage directive (2014/35/EU), and its mechanical construction conforms to IP20 ingress protection rating for indoor dry-lab environments.

Software & Data Management

While the KRS-DS21-6 operates via embedded hardware control (no external PC dependency), its digital interface supports audit-ready manual logging: temperature setpoint, actual reading, date/time stamp, and operator ID can be recorded in laboratory notebooks or LIMS-integrated spreadsheets. For facilities requiring electronic records compliant with FDA 21 CFR Part 11, optional RS-485 serial output (available upon request with KRS-DS21-6-EXT variant) enables connection to validated data acquisition systems. All firmware implements write-protected calibration constants traceable to NIST-certified reference thermometers, with calibration verification intervals recommended every 6 months per ISO/IEC 17025 Clause 6.6.

Applications

• Pre-incubation of microbial culture media (e.g., TSB, Mueller-Hinton agar) at 35–37 °C prior to pour plating
• Controlled hydrolysis of ester-based prodrugs during pharmaceutical stability studies (ICH Q1A)
• Enzyme kinetic assays requiring precise thermal stabilization of reaction mixtures (e.g., LDH, ALP, amylase)
• Standardization of viscosity reference oils per ASTM D445 before rotational viscometer calibration
• Environmental sample digestion (EPA Method 3015A) using hot water bath pretreatment prior to acid digestion
• Controlled thawing of cryopreserved cell lines and serum batches under GMP Annex 1 thermal mapping guidelines

FAQ

What is the maximum fill level for optimal thermal uniformity?
For ≤±0.1 °C inter-well consistency, maintain water level between 20 mm below the rim and 10 mm above the bottom of immersed vessels.
Can this unit operate continuously for 72+ hours?
Yes—its sealed chamber and thermal cutoff architecture support unattended operation; however, weekly visual inspection of water level and scaling is required per maintenance SOPs.
Is the temperature sensor calibrated at the factory?
Each unit ships with a certificate of conformance listing initial calibration against a Fluke 1523 Standard Thermometer at 37 °C and 60 °C points.
Does the bath support external temperature probes for independent validation?
No native port exists, but third-party PT100 sensors can be mounted externally using non-invasive clamps and logged via separate dataloggers.
What cleaning agents are compatible with the stainless steel bath?
Use only neutral pH detergents (e.g., Alconox Liquinox) or 70% ethanol; avoid chloride-based cleaners to prevent pitting corrosion.