Lanbo AS Multifunctional Autosampler for HPLC Systems
| Origin | USA |
|---|---|
| Manufacturer Type | Authorized Distributor |
| Origin Category | Imported |
| Model | Lanbo AS |
| Instrument Type | Liquid Chromatography Autosampler |
| Compliance | Designed for ASTM D4790, USP <621>, and ISO 17025-accredited laboratories |
Overview
The Lanbo AS Multifunctional Autosampler is a precision-engineered sample introduction system designed for integration with high-performance liquid chromatography (HPLC) and ultra-high-performance liquid chromatography (UHPLC) platforms. It operates on a syringe-based, positive-displacement sampling principle—ensuring minimal carryover, high volumetric accuracy, and reproducible injection volumes across diverse matrix types. Engineered for routine QC/QA workflows and regulated research environments, the AS series supports both single- and multi-vial batch processing with programmable injection sequences, variable loop filling, and temperature-controlled sample storage. Its modular architecture allows seamless compatibility with major OEM detectors and data systems without proprietary lock-in.
Key Features
- Programmable injection volume range from 0.1 µL to 100 µL with ±0.3% volumetric accuracy (traceable to NIST-certified standards)
- Sample capacity up to 120 positions using standard 2-mL vials or customizable trays for 96-well microplates
- Integrated Peltier-cooled sample compartment (4–40 °C, ±0.5 °C stability) to preserve thermolabile analytes during extended runs
- Low carryover (<0.005%) achieved via dual-rinse solvent pathways, active needle wash stations, and inert flow path materials (PEEK, sapphire, and fused silica)
- Auto-calibration routine for syringe positioning and loop volume verification, supporting GLP-compliant audit trails
- RS-232, USB, and Ethernet interfaces for bidirectional communication with chromatography data systems (CDS), including Empower, Chromeleon, and OpenLab CDS
Sample Compatibility & Compliance
The Lanbo AS accommodates a broad range of sample formats—including aqueous buffers, organic solvents, viscous biological matrices (e.g., plasma, serum, cell lysates), and particulate-containing suspensions—without compromising injection integrity. All wetted components comply with USP Class VI biocompatibility requirements and resist corrosion from aggressive mobile phases (e.g., TFA, HFIP, high-pH ammonium bicarbonate). The system meets mechanical and electrical safety standards per IEC 61010-1 and is validated for use in laboratories adhering to FDA 21 CFR Part 11, EU Annex 11, and ISO/IEC 17025 requirements. Optional IQ/OQ documentation packages are available to support installation and operational qualification under GMP environments.
Software & Data Management
Controlled via Lanbo ControlSuite™ v3.2—a Windows-based application supporting method development, sequence building, real-time monitoring, and event logging—the autosampler enables full traceability of all user actions, instrument states, and calibration events. Audit trail functionality records timestamps, operator IDs, parameter changes, and error conditions in an immutable format compliant with ALCOA+ principles. Data export is supported in CSV, XML, and vendor-neutral AIA/ANDI formats. Remote diagnostics and firmware updates are performed securely over HTTPS, with role-based access control (RBAC) for multi-user labs.
Applications
- Routine pharmaceutical assay validation and stability-indicating methods per ICH Q2(R2)
- Environmental analysis of pesticides, PAHs, and pharmaceutical residues in wastewater per EPA Method 8330B and ISO 14644-1
- Food safety testing for mycotoxins, preservatives, and sweeteners in compliance with EU Regulation (EC) No 401/2006
- Biopharmaceutical characterization—including monoclonal antibody purity assessment, peptide mapping, and glycan profiling—using reversed-phase and HILIC gradients
- Academic and industrial metabolomics workflows requiring unattended overnight sequencing of >500 biological extracts
FAQ
Does the Lanbo AS support partial-loop injections for low-volume samples?
Yes—partial-loop mode enables accurate delivery of sub-microliter volumes using calibrated air gaps and pressure-compensated aspiration protocols.
Can it be retrofitted onto legacy HPLC systems not listed in the compatibility matrix?
Integration is possible via TTL-triggered external start signals and analog voltage inputs; contact technical support for interface validation.
Is method transfer between Lanbo AS and other autosamplers feasible?
Method parameters—including dwell time, rinse cycles, and injection speed—are exportable and manually translatable to most CDS platforms, though retention time alignment requires column and gradient re-optimization.
What maintenance intervals are recommended for optimal long-term performance?
Syringe and seal replacement every 10,000 injections; needle seat inspection every 5,000 injections; full system leak test and calibration verification quarterly or after any hardware service event.
