Metler Toledo RAININ Pipet-Lite XLS+ 8-Channel Manual Pipettor
| Brand | RAININ |
|---|---|
| Origin | USA |
| Model | Mettler Toledo Pipet-Lite XLS+ 8-Channel Pipettor |
| Automation Level | Manual |
| Channels | 8 |
| Volume Range | 0.5–300 µL |
| Max Capacity | 300 µL |
| Accuracy | ±4% at 1 µL, ±0.8% at 50 µL, ±0.8% at 300 µL |
Overview
The Mettler Toledo RAININ Pipet-Lite XLS+ 8-Channel Manual Pipettor is an ergonomically engineered precision liquid handling instrument designed for high-throughput, repetitive pipetting tasks in regulated laboratory environments—including QC, clinical diagnostics, genomics, and pharmaceutical development. Based on positive displacement piston-driven mechanics, it delivers consistent volumetric delivery across all eight channels without reliance on electronic actuation or external power sources. Its core design philosophy centers on minimizing operator-induced variability—addressing fatigue-related errors, inter-channel inconsistency, and calibration drift—through mechanical innovation rather than software compensation. The device complies with ISO 8655-2 (volumetric accuracy) and ISO 8655-5 (repeatability), serving as a foundational tool for GLP/GMP-aligned workflows where traceability, reproducibility, and manual technique standardization are critical.
Key Features
- Ergonomic lightweight construction—up to 35% lighter than prior-generation multi-channel pipettors—reduces hand and wrist strain during extended use.
- Patented Lite-Touch System (LTS) tip interface ensures low-force tip attachment and ejection, with consistent sealing integrity across >10,000 cycles.
- Magnetic-assisted plunger mechanism eliminates “piston stickiness,” enabling smooth, linear actuation with minimal required force (≤1.2 N at full stroke).
- Tool-free volume adjustment with tactile feedback and glove-compatible dial; prevents accidental volume drift during operation.
- Integrated RFID chip (ISO/IEC 15693 compliant) stores calibration history, service records, and user-defined configurations—enabling audit-ready traceability without external databases.
- Chemically resistant high-density polymer tip ejector withstands autoclaving (121°C, 20 min), repeated exposure to organic solvents, and mechanical abrasion.
- Inter-channel consistency maintained within ±0.3% CV at nominal volume—verified per ISO 8655-6 testing protocols.
Sample Compatibility & Compliance
The Pipet-Lite XLS+ is validated for aqueous, viscous (up to 50 cP), and moderately volatile liquids (e.g., ethanol/water mixtures, PBS, cell culture media). It supports LTS and universal conical tips (0.1–1000 µL range), with optimal performance achieved using RAININ-certified LTS tips. All materials contacting fluid paths comply with USP Class VI biocompatibility standards. Device firmware and RFID data architecture support 21 CFR Part 11 compliance when integrated with RAININ’s LiteTouch Software and validated LIMS interfaces. Calibration documentation meets ISO/IEC 17025 requirements for accredited laboratories.
Software & Data Management
While the XLS+ operates manually, its embedded RFID tag enables seamless integration with RAININ’s LiteTouch Software (v3.2+), allowing centralized tracking of calibration due dates, maintenance logs, and user-specific volume presets. Data export supports CSV and XML formats compatible with enterprise quality management systems (QMS). Audit trails include timestamped calibration events, technician ID, environmental conditions (temperature/humidity), and pass/fail verification against ISO 8655 tolerances. No local storage or cloud dependency is required—the chip retains up to 100 calibration entries onboard.
Applications
- High-density plate preparation for ELISA, qPCR, and cell-based assays.
- Serial dilution workflows requiring strict inter-channel uniformity (e.g., IC50 determination, potency testing).
- Sample normalization in proteomics and metabolomics sample prep pipelines.
- Regulated release testing under pharmacopeial methods (USP <1051>, EP 2.6.17).
- Training environments where reproducible manual technique must be objectively quantified and reinforced.
FAQ
Is the Pipet-Lite XLS+ compatible with non-LTS tips?
Yes—universal conical tips may be used, though accuracy and tip seal integrity are optimized only with RAININ LTS tips per ISO 8655-3 validation.
Does the RFID chip require a battery or external reader?
No—it is passive RFID (13.56 MHz) and powered wirelessly by compatible readers; no internal power source is needed.
Can the XLS+ be calibrated in-house?
Yes—calibration follows ISO 8655-6 gravimetric procedures; RAININ provides certified calibration kits and SOP templates aligned with ISO/IEC 17025.
What sterilization methods are supported?
Autoclaving at 121°C for 20 minutes is validated for the main body and tip ejector; the plunger assembly must be disassembled and sterilized separately per RAININ Technical Bulletin TB-027.
How does the XLS+ ensure channel-to-channel consistency over time?
Through monolithic front-end machining, preloaded torsion springs with matched torque profiles, and factory-balanced piston alignment—verified via multi-point inter-channel deviation mapping during final QA.
