Metrohm 925 CN Ion Chromatograph
| Brand | Metrohm |
|---|---|
| Origin | Shanghai, China |
| Manufacturer Type | Manufacturer |
| Origin Category | Domestic (China) |
| Model | 925 CN |
| Instrument Type | Laboratory |
| Application Scope | General-purpose |
| Pump Pressure Rating | 50 MPa |
| Flow Rate Range | 0.001–20.000 mL/min |
| Eluent Flow Rate | 0.001–20 mL/min |
| Maximum Operating Pressure | 35 MPa (5000 psi) |
| Operating Temperature Range | 20–50 °C |
| Temperature Reproducibility | ±0.2 °C |
| Eluent Concentration Range | 0–100% |
Overview
The Metrohm 925 CN Ion Chromatograph is a robust, entry-level analytical system engineered for routine anion and cation analysis in environmental, educational, and quality control laboratories. Based on Metrohm’s proven ion chromatography platform, it employs suppressed conductivity detection with chemical suppression—ensuring high sensitivity and selectivity for inorganic ions (e.g., Cl⁻, NO₃⁻, SO₄²⁻, Na⁺, K⁺, NH₄⁺) and small polar molecules (e.g., formate, acetate). Unlike research-grade systems, the 925 CN prioritizes operational stability, ease of validation, and long-term serviceability over ultra-high resolution or multi-detector flexibility. Its modular architecture integrates a high-pressure dual-piston pump, thermostatically controlled column oven, electrochemical conductivity detector, and integrated suppressor—all housed in a compact, benchtop enclosure designed for Class 10,000 cleanroom-compatible lab environments.
Key Features
- High-pressure gradient-capable pump rated to 50 MPa, with precise flow control from 0.001 to 20.000 mL/min (reproducibility ≤0.1% RSD)
- Column compartment with active temperature regulation (20–50 °C), maintaining ±0.2 °C stability across 8-hour continuous operation
- Integrated chemical suppressor compatible with Metrosep A Supp 17 and other Metrohm-certified columns—enabling low-noise baseline performance and sub-µg/L detection limits for common anions
- Real-time system health monitoring: automatic logging of injection count, cumulative pump runtime, pressure trends, and eluent consumption
- Intelligent backpressure management that dynamically adjusts flow or triggers alerts when column blockage risk exceeds ISO 17025-defined thresholds
- Modular expansion support for automation via the 863 CN Compact Autosampler (36-position capacity) and Inline Ultrafiltration (iUF) for particulate-laden samples such as wastewater, soil extracts, or beverage matrices
Sample Compatibility & Compliance
The 925 CN accommodates aqueous samples with total suspended solids (TSS) <5 ppm when used with iUF pre-treatment; direct injection is supported for filtered potable water, rainwater, and standard reference materials (SRMs). It complies with ASTM D4327 (anion analysis in water), ISO 10304-1 (determination of dissolved anions), and USP (conductivity testing of purified water). All hardware and firmware are validated per ICH Q2(R2) guidelines for method suitability. The instrument meets GLP requirements through full audit trail functionality—including user login/logout timestamps, parameter change history, and electronic signature support—as mandated by FDA 21 CFR Part 11 when deployed with MagIC Net v3.3 or later.
Software & Data Management
Controlled exclusively by MagIC Net software (v3.3+), the 925 CN delivers traceable, compliant data handling. The workstation supports automated calibration curve generation, peak integration using ISO 14155-compliant algorithms, and customizable reporting templates aligned with ISO/IEC 17025 documentation standards. Each analysis session records metadata including ambient lab temperature, detector cell temperature, suppressor regeneration status, and raw conductivity signal drift. Software updates are provided for five years post-discontinuation; spare parts—including suppressor cartridges and detector cells—are guaranteed available for ten years from first shipment. Remote diagnostics and firmware updates are accessible via secure TLS 1.3 connections without exposing internal network infrastructure.
Applications
- Drinking water and wastewater compliance testing (EPA Method 300.1, ISO 10304-3)
- Academic teaching labs: hands-on training in separation science principles, detector response modeling, and regulatory data integrity practices
- Pharmaceutical excipient testing (chloride, sulfate, acetate in APIs per ICH Q5C)
- Food and beverage quality assurance (nitrate in vegetables, phosphate in dairy products)
- Electrolyte formulation verification in battery R&D (Li⁺, F⁻, PF₆⁻ quantification in non-aqueous solvents after dilution)
FAQ
Is the 925 CN suitable for regulated GMP environments?
Yes—when configured with MagIC Net v3.3+, enabled audit trail, and validated SOPs, it satisfies FDA 21 CFR Part 11 and EU Annex 11 requirements for electronic records and signatures.
Can I use non-Metrohm columns with this system?
Mechanically compatible with standard 1/4″ or 1/8″ fittings, but only Metrohm-certified columns (e.g., Metrosep A Supp 17, C 4, or IC-Ag) are covered under warranty and method transfer support.
What is the expected lifetime of the suppressor module?
The anion suppressor rotor carries a 10-year limited warranty; typical field life exceeds 8,000 injections under EPA-recommended eluent conditions (KOH, 5–30 mM).
