Nichiryo DISPET EX II High-Pressure & High-Temperature Bottle Top Dispenser

Overview

The Nichiryo DISPET EX II is a precision-engineered manual bottle top dispenser designed for reliable, repeatable liquid dispensing under demanding laboratory conditions—including elevated pressure and temperature environments. Unlike standard dispensers limited to ambient operation, the DISPET EX II integrates a reinforced mechanical architecture with chemically inert, high-performance sealing materials (FFKM elastomers and PTFE-coated piston assemblies) to maintain volumetric integrity when dispensing volatile, viscous, or thermally sensitive reagents from pressurized or heated reservoirs. Its operation follows the positive displacement principle: rotation of the calibrated volume dial advances a precision-machined piston within a sealed cylinder, displacing an exact volume of liquid per stroke—eliminating reliance on gravity or atmospheric pressure. This makes it particularly suitable for use with solvent bottles under nitrogen blanket, autoclaved reagent containers, or high-boiling-point media requiring preheating prior to transfer.

Key Features

• Robust pressure-rated design certified for continuous operation up to 6 bar (87 psi), enabling safe dispensing from pressurized solvent dispensing systems or gas-purged reagent bottles.
• Thermal stability validated to 120 °C, supporting direct mounting onto pre-warmed bottles containing hot solvents (e.g., molten paraffin, heated DMSO, or sterilized aqueous buffers).
• High-accuracy volumetric delivery across the full 0.2–10 mL range, with a minimum graduation of 0.05 mL and guaranteed accuracy of ±0.1% of full-scale value—traceable to JIS B 7902 and ISO 8655-3 standards for piston-operated dispensers.
• Chemical resistance achieved via FFKM (perfluoroelastomer) seals and PTFE-coated stainless steel piston, ensuring compatibility with aggressive solvents including concentrated acids, halogenated hydrocarbons, and strong bases.
• Ergonomic dual-grip handle with tactile volume dial and integrated locking collar prevents accidental volume drift during repetitive dispensing tasks.
• Quick-release bayonet mount compatible with GL45, GL32, and GL25 standard bottle neck threads; includes universal adapter kit for non-standard container interfaces.

Sample Compatibility & Compliance

The DISPET EX II accommodates a broad spectrum of liquid classes: low-viscosity solvents (acetone, methanol), moderately viscous solutions (glycerol/water mixtures up to 1,000 mPa·s), and suspensions with particles <5 µm in diameter—provided the suspension remains stable during dispensing. It is not intended for abrasive slurries, crystallizing solutions, or liquids containing undissolved solids >10 µm. The device complies with ISO 8655-3 (volumetric accuracy), JIS B 7902 (Japanese industrial standard for dispensers), and meets material safety requirements under REACH Annex XVII and RoHS Directive 2011/65/EU. All wetted parts are non-leaching and extractables-tested per USP <661.1>, supporting use in analytical sample preparation and QC workflows under GLP conditions.

Software & Data Management

As a fully mechanical, non-electronic instrument, the DISPET EX II requires no firmware, drivers, or software integration. Volume setting, calibration verification, and maintenance logs are documented manually using the included calibration certificate template and traceable logbook format aligned with ISO/IEC 17025 documentation practices. For laboratories operating under FDA 21 CFR Part 11, the dispenser supports audit-ready recordkeeping when paired with electronic lab notebooks (ELNs) that capture operator ID, date/time stamp, and volume settings per dispensing event. Optional calibration services include NIST-traceable certificate issuance with uncertainty budgeting.

Applications

• Precise dispensing of calibration standards and reference materials in ICP-MS, HPLC, and GC sample preparation where thermal expansion or vapor pressure affects gravimetric accuracy.
• Safe handling of pyrophoric or air-sensitive reagents (e.g., t-BuLi, DIBAL-H) stored under inert gas pressure—eliminating exposure risks associated with syringe transfer.
• Reproducible addition of viscous catalyst solutions (e.g., Grubbs’ catalyst in chlorobenzene) in synthetic chemistry workflows requiring strict stoichiometric control.
• Quality control of pharmaceutical excipients and active ingredients in hot-melt extrusion process development, where melt-phase dispensing at elevated temperatures is required.
• Environmental testing labs dispensing preserved water samples (e.g., acidified metals standards) directly from pressurized storage carboys.

FAQ

Can the DISPET EX II be autoclaved?
No—the entire unit is not autoclavable. However, the dispensing head (piston assembly and nozzle) may be disassembled and sterilized via dry heat (120 °C for 60 min) or ethylene oxide; refer to the maintenance manual for component-specific validation protocols.
Is calibration required before first use?
Yes. Each unit ships with a factory calibration certificate. Users must perform initial verification using certified Class A volumetric flasks and distilled water at 20 °C, following ISO 8655-6 procedures.
What bottle thread sizes does it support out of the box?
Standard configuration includes GL45 (45 mm) mounting; optional adapters for GL32 and GL25 are provided in the accessory kit.
Does it comply with ISO/IEC 17025 for accredited testing labs?
Yes—when used with documented calibration, traceable standards, and controlled environmental conditions (20 ± 1 °C, 45–65% RH), the DISPET EX II satisfies metrological requirements for accredited volumetric dispensing in testing laboratories.
Can it dispense hydrofluoric acid (HF)?
No. Although FFKM seals offer broad chemical resistance, HF attacks glass-reinforced PPS components and compromises structural integrity; use only with HF-compatible alternatives (e.g., all-PTFE dispensers) for such applications.