Nichiryo MODEL2100DG Digital Handheld Continuous Dispenser
| Brand | Nichiryo |
|---|---|
| Origin | Japan |
| Model | MODEL2100DG |
| Type | Manual Multi-Channel Continuous Dispenser |
| Dispensing Range Options | 0.2–1.0 mL (00-21DG-1), 0.4–2.0 mL (00-21DG-2), 1.0–5.0 mL (00-21DG-5), 2.0–10.0 mL (00-21DG-10) |
| Minimum Increment | 0.01–0.10 mL depending on model |
| Display Resolution | 0.01 mL (DG-1/DG-2), 0.02 mL (DG-5), 0.10 mL (DG-10) |
| Fluid Contact Materials | PTFE, Tygon® tubing, polypropylene, Pyrex® glass, ceramic, platinum-iridium alloy |
| Housing | Impact-resistant polymer shell protecting internal glass and piston components |
| Ergonomics | Single-hand operation, lightweight design (<300 g) |
Overview
The Nichiryo MODEL2100DG Digital Handheld Continuous Dispenser is a precision-engineered manual liquid handling instrument designed for repeatable, stepless volumetric dispensing across multiple laboratory workflows. Unlike conventional fixed-volume or single-channel pipettes, the MODEL2100DG operates on a calibrated syringe-based positive displacement principle: rotation of the digital volume dial advances a precision-machined piston within a chemically inert glass or ceramic barrel, driving fluid through interchangeable dispensing tips or tubing assemblies. This architecture ensures minimal dead volume, high reproducibility (CV < 1.5% at nominal setting), and compatibility with viscous, volatile, corrosive, or particulate-laden liquids—conditions where air-displacement pipettes exhibit significant error. Its modular configuration supports both open-vessel dispensing and closed-system integration via Luer-lock or barbed fittings, making it suitable for applications ranging from QC sample preparation to analytical reagent addition in regulated environments.
Key Features
- Digital volume display with tactile feedback dial enabling rapid, parallax-free setting verification under bench lighting or hood illumination
- Four interchangeable dispensing modules (DG-1, DG-2, DG-5, DG-10) covering total ranges from 0.2–10.0 mL with resolution down to 0.01 mL
- Chemically resistant fluid path constructed entirely from USP Class VI-certified materials: PTFE seals, Tygon® R-3603 or R-1000 tubing, autoclavable polypropylene housing, Pyrex® borosilicate glass barrels, and platinum-iridium piston tips for extreme pH or halogenated solvent resistance
- Integrated impact-absorbing polymer overmold protecting fragile glass and ceramic components during routine handling and transport
- Ergonomic grip geometry validated per ISO 9241-400 guidelines for sustained single-hand use over extended dispensing sessions (tested up to 200+ actuations/hour)
- No battery or external power required—fully mechanical operation ensures zero drift and long-term calibration stability
Sample Compatibility & Compliance
The MODEL2100DG accommodates aqueous buffers, organic solvents (including acetone, DMSO, chloroform), concentrated acids (up to 6 M HCl, 14 M HNO₃), bases (up to 10 M NaOH), and suspensions containing particles ≤50 µm. Its material compatibility aligns with ASTM D543 and ISO 10993-5 standards for chemical resistance testing. The device meets ISO 8655-3 requirements for positive displacement dispensers and supports GLP/GMP documentation through traceable serial-numbered calibration certificates (available upon request). While not electronically audit-trail capable, its mechanical design inherently satisfies FDA 21 CFR Part 11 §11.10(a) criteria for “non-electronic records” where handwritten logs or integrated LIMS entries document usage and calibration status.
Software & Data Management
As a fully manual, non-electronic instrument, the MODEL2100DG does not incorporate embedded firmware, Bluetooth, or USB connectivity. Volume settings are recorded manually in lab notebooks or electronic lab notebooks (ELNs) alongside batch identifiers and operator initials. Calibration data—including date, reference standard used (e.g., NIST-traceable gravimetric measurement), and deviation values—is retained per ISO/IEC 17025 clause 7.7. Each unit ships with a factory calibration report referencing JIS Z 8015-2016 methodology. Users may perform field verification using certified volumetric flasks or digital balance-based gravimetric checks per ISO 8655-6 Annex B protocols.
Applications
- Preparation of calibration standards and QC samples in environmental, pharmaceutical, and food testing laboratories
- Serial dilution workflows requiring consistent inter-step volume fidelity (e.g., ELISA plate setup, microbial suspension plating)
- Addition of catalysts, initiators, or crosslinkers in polymer synthesis where metered stoichiometric control is critical
- Dispensing of cytotoxic or radioactive reagents in shielded gloveboxes—enabled by its compact footprint and absence of electronic components
- Field-deployable liquid handling in mobile analytical units where power independence and shock resistance are operational imperatives
FAQ
Is the MODEL2100DG compatible with ethanol and isopropanol?
Yes—Tygon® R-3603 tubing and PTFE seals provide continuous service life exceeding 10,000 cycles in 100% IPA or ethanol at ambient temperature.
Can it be sterilized in an autoclave?
The polypropylene housing and Pyrex® glass barrel are autoclavable at 121°C, 15 psi for 20 minutes; however, Tygon® tubing and PTFE components must be removed prior to sterilization.
What is the recommended recalibration interval?
Annual recalibration is advised for GxP environments; for non-regulated research use, verification before each high-value assay series is sufficient per ISO 8655-6 guidance.
Does Nichiryo supply OEM replacement parts?
Yes—barrels, pistons, seals, and tubing kits are available under part numbers corresponding to each DG-series module (e.g., DG-1-SEAL-KIT, DG-5-BARREL-ASSY).
How is volume accuracy verified without electronic output?
Gravimetric verification using Class I analytical balances (±0.0001 g readability) and certified water density tables per ISO 8655-6 provides direct traceability to SI units.
