PUREN PIC-10 Ion Chromatograph
| Brand | PUREN |
|---|---|
| Origin | Shandong, China |
| Manufacturer Type | Direct Manufacturer |
| Instrument Type | Laboratory Benchtop Ion Chromatograph |
| Application Scope | General-Purpose Anion/Cation Analysis |
| Maximum Pump Pressure | 0–42.0 MPa (Stainless Steel), 0–35 MPa (PEEK) |
| Flow Rate Range | 0.001–9.999 mL/min (0.001 mL/min increments) |
| Eluent Flow Rate | 0.7–1.5 mL/min |
| Max System Operating Pressure | 10 MPa (1500 psi) |
| Column Oven Temperature Range | 5–65 °C |
| Eluent Concentration Range | 1.92–4.8 mM |
Overview
The PUREN PIC-10 Ion Chromatograph is a compact, integrated benchtop system engineered for high-reproducibility anion and cation analysis using suppressed conductivity detection. Based on the principle of ion-exchange chromatography coupled with post-column electrochemical suppression and conductivity measurement, the PIC-10 delivers quantitative separation and detection of inorganic ionic species in aqueous matrices. Its modular architecture integrates a microprocessor-controlled dual-piston reciprocating pump, a PEEK-based low-dead-volume fluidic path, a patented column–detector thermostatic module (Patent No. ZL200820019630.3), and a continuously regenerated electrochemical membrane suppressor (pH 0–14 compatible). Designed for routine QC/QA and regulatory-compliant environmental and industrial testing, the system supports both isocratic and gradient elution — including up to quaternary solvent programming — and enables sequential or concurrent anion/cation analysis via user-selectable separation columns.
Key Features
- Integrated thermostatic module housing both separation column and conductivity detector, ensuring thermal stability and baseline reproducibility across ambient temperature fluctuations.
- Dual-material high-pressure pump: stainless steel head for >40 MPa capability; PEEK head for compatibility with aggressive eluents (e.g., strong acids/bases and 100% organic solvents).
- Continuous electrochemical regeneration membrane suppressor: zero chemical consumption, <1.5 nS background conductivity, 5,000 injections without maintenance.
- Full PEEK fluidic path (imported components): chemically inert to HNO₃, NaOH, KOH, methanol, acetonitrile, and mixed aqueous–organic mobile phases.
- Intelligent flow control algorithm minimizing pulsation (<0.1% RSD at 1.0 mL/min), supporting precise low-flow applications down to 0.001 mL/min.
- USB 2.0 digital interface with embedded high-resolution ADC (24-bit) for real-time data acquisition, instrument remote control, and parameter synchronization.
Sample Compatibility & Compliance
The PIC-10 accommodates direct injection of clarified aqueous samples — including drinking water, wastewater, soil extracts, pharmaceutical buffers, petrochemical process streams, and food digestates — without derivatization. It complies with method requirements outlined in ISO 10304-1 (determination of anions in water), ASTM D4327 (anion analysis by IC), USP (conductivity of purified water), and EPA Methods 300.0 and 317.0. The system supports 21 CFR Part 11–ready audit trails when used with validated software configurations, and its hardware design conforms to IEC 61010-1 safety standards for laboratory electrical equipment. All wetted materials meet USP Class VI biocompatibility criteria.
Software & Data Management
The dedicated PUREN IC Workstation v3.x provides full instrument control, real-time chromatogram visualization, peak integration, calibration curve generation (linear/logarithmic), and customizable reporting per ISO/IEC 17025 documentation requirements. Key functions include automatic baseline correction, negative peak recognition, adaptive integration window adjustment, electronic signature support, and metadata-embedded data archiving (.icd binary + .csv export). The software logs all method changes, detector responses, pressure events, and temperature deviations with timestamps — enabling traceability for GLP/GMP audits. Remote diagnostics and firmware updates are supported via secure HTTPS protocol.
Applications
- Environmental monitoring: simultaneous quantification of F⁻, Cl⁻, NO₂⁻, Br⁻, NO₃⁻, PO₄³⁻, SO₄²⁻, ClO₂⁻, ClO₃⁻, BrO₃⁻ in surface water, groundwater, and effluent per EPA guidelines.
- Pharmaceutical quality control: assay of counterions (Na⁺, K⁺, NH₄⁺) in APIs; residual acetate, citrate, or phosphate in formulations.
- Food & beverage safety: detection of preservative anions (benzoate, sorbate), nitrite in cured meats, iodide in dairy, and sulfite in wine.
- Power generation: chloride and sulfate monitoring in boiler feedwater and steam condensate to prevent corrosion.
- Geological research: multi-cation profiling (Li⁺, Ca²⁺, Mg²⁺, Sr²⁺, Ba²⁺) in brine and leachate samples using methanesulfonic acid eluents.
FAQ
What eluent concentrations does the PIC-10 support for standard anion analysis?
The system operates optimally with carbonate/bicarbonate or hydroxide-based eluents within 1.92–4.8 mM concentration range, adjustable via software-controlled pump mixing ratios.
Can the PIC-10 perform both anion and cation analysis on a single platform?
Yes — by installing a cation-exchange column and switching to methanesulfonic acid eluent, users can reconfigure the system for sequential cation analysis without hardware modification.
Is the suppressor compatible with high-pH eluents such as potassium hydroxide?
Yes — the electrochemical membrane suppressor maintains full functionality across pH 0–14, including concentrated KOH gradients up to 100 mM.
Does the system meet regulatory requirements for electronic records and signatures?
When deployed with validated workstation settings and enabled audit trail logging, the PIC-10 supports compliance with 21 CFR Part 11, Annex 11, and ISO/IEC 17025 documentation integrity requirements.
What maintenance intervals are recommended for the PEEK fluidic system?
Under normal use (≤8 h/day, filtered samples), the PEEK tubing, fittings, and pump seals require inspection every 6 months; suppressor lifetime exceeds 2 years with continuous regeneration.
