Rainin LTS and RAININ XLS+ Pipette Tips by METTLER TOLEDO
| Brand | METTLER TOLEDO |
|---|---|
| Origin | Switzerland |
| Product Line | Rainin® |
| Tip Compatibility | LTS (Low-Torque Seal) and XLS+ platforms |
| Sterilization | Autoclavable (121°C, 20 min) |
| Material | Medical-grade polypropylene (PP) for tips |
| Volume Range | 10 µL, 250 µL, 1000 µL |
| Packaging Formats | Green-Pak™ single-box refills (96 tips), SpaceSaver™ stackable refills (8 or 10 trays per pack), TerraRack™ 100% recyclable racks, Bulk bags (1,000 tips/bag, 10 bags/box = 10,000 tips), StableStak™ high-density stacking system (768 tips per 10×96 configuration), StableRack™ dual-96 format (35% less plastic vs. two standard racks) |
| Regulatory Compliance | ISO 8573-1 Class 0 certified air purity, DNase/RNase-free, non-pyrogenic, tested per ASTM D257 (surface resistivity), USP <85> endotoxin testing ≤0.03 EU/mL |
Overview
Rainin pipette tips—engineered and manufactured by METTLER TOLEDO in Switzerland—are precision liquid handling consumables designed exclusively for compatibility with Rainin’s LTS (Low-Torque Seal) and XLS+ pipette systems. These tips utilize a proprietary conical geometry and optimized wall thickness to ensure consistent, leak-free sealing under low insertion force—reducing operator fatigue and minimizing tip ejection variability across repeated use. Each tip is injection-molded under cleanroom conditions (ISO 7 / Class 10,000) and subjected to 100% automated optical inspection for dimensional integrity, tip concentricity, and orifice uniformity. The design adheres to the ISO 8655-2:2022 standard for pipette performance verification, supporting traceable volumetric accuracy when used with calibrated Rainin pipettes. Unlike generic alternatives, Rainin tips undergo rigorous functional validation—including aspiration/dispense repeatability testing across temperature gradients (15–30°C) and humidity ranges (30–70% RH)—to guarantee reproducibility in regulated environments such as GLP-compliant labs and pharmaceutical QC workflows.
Key Features
- Low-torque sealing interface ensures secure attachment with ≤30% less insertion force than universal-fit tips—critical for ergonomic high-throughput workflows.
- Autoclavable at 121°C for 20 minutes without deformation or seal degradation; validated for ≥5 sterilization cycles in controlled studies.
- TerraRack™ storage systems constructed from 100% post-industrial PETE, fully recyclable via standard municipal streams (ASTM D7611-compliant).
- Green-Pak™ refills feature individually sealed, blister-packed 96-tip units—eliminating secondary packaging waste and enabling just-in-time replenishment without contamination risk.
- SpaceSaver™ refill packs integrate 8 or 10 nested trays in compact footprint; each tray maintains ANSI/SLAS microplate footprint (127.76 × 85.48 mm) for robotic arm compatibility.
- StableStak™ stacking architecture enables vertical consolidation of up to 10×96-tip racks (768 tips), reducing benchtop footprint by 62% versus staggered rack arrangements.
- StableRack™ dual-96 format replaces two conventional racks with one integrated carrier—cutting plastic mass by 35% while preserving full ANSI/SLAS alignment and barcode readability.
Sample Compatibility & Compliance
Rainin tips are certified DNase-, RNase-, and endotoxin-free (USP , ≤0.03 EU/mL), with batch-specific certificates of analysis provided for every production lot. All tips meet ISO 11137-1:2018 requirements for radiation sterilization validation (where applicable) and comply with ISO 13485:2016 quality management standards for medical device manufacturing. Racks and packaging materials conform to RoHS Directive 2011/65/EU and REACH Annex XVII restrictions on SVHC substances. For regulated bioprocessing applications, Rainin tips support 21 CFR Part 11–compliant electronic record retention when used with Rainin’s Liquidator™ software and compatible LIMS integrations.
Software & Data Management
While tips themselves are passive consumables, their traceability is embedded within METTLER TOLEDO’s LabX® Liquid Handling Suite. Batch numbers, sterilization logs, and COA metadata can be scanned via integrated QR codes on Green-Pak™ and TerraRack™ packaging and automatically synchronized with LabX audit trails. This linkage supports ALCOA+ data integrity principles—ensuring Attributable, Legible, Contemporaneous, Original, Accurate, Complete, Consistent, Enduring, and Available records for FDA inspections. Rack-level barcodes also enable automated inventory reconciliation in robotic workcells using Rainin’s LiteTouch™ controller firmware v4.2+.
Applications
These tips serve critical roles in quantitative molecular biology workflows—including qPCR setup, NGS library preparation, ELISA plate loading, and cell culture media dispensing—where surface consistency and hydrophobicity control directly impact droplet formation and carryover. Their low-binding polypropylene formulation minimizes adsorption of proteins (e.g., BSA, IgG) and nucleic acids (<0.5 ng/mL loss in 10 µL transfers), making them suitable for low-volume assays requiring sub-microliter precision. In clinical diagnostics, the validated endotoxin profile supports sterile sample transfer in ISO 15189-accredited pathology labs. High-density formats (StableStak™, StableRack™) are routinely deployed in HTS screening facilities operating under ICH-GCP guidelines.
FAQ
Are Rainin tips compatible with non-Rainin pipettes?
No. Rainin LTS and XLS+ tips are engineered for mechanical and thermal interoperability only with Rainin-branded pipettes. Use with third-party instruments may compromise seal integrity, volume accuracy, or tip ejection reliability.
Can TerraRack™ be autoclaved?
No. TerraRack™ is made from PETE and is not autoclavable. Only polypropylene-based tips and RT-series racks are rated for steam sterilization.
What is the shelf life of unopened Green-Pak™ refills?
Three years from manufacture date when stored at 15–30°C and ≤60% relative humidity, per ISO 11607-1:2019 packaging stability testing.
Do bulk bagged tips require re-sterilization before use?
No. Bulk bags are gamma-irradiated (25 kGy) and supplied with ISO 11137-2:2013 sterilization dose mapping reports. They are ready-to-use upon opening in ISO Class 5 laminar flow hoods.
How does StableRack™ achieve 35% plastic reduction?
Through structural topology optimization: shared sidewalls, eliminated redundant labeling surfaces, and consolidated hinge mechanisms—verified via Life Cycle Assessment (LCA) per ISO 14040:2006.


