Rainin Pipet-Lite XLS+ Manual Single-Channel Pipette

Overview

The Rainin Pipet-Lite XLS+ Manual Single-Channel Pipette is an engineered precision liquid handling instrument designed for high-reproducibility manual pipetting in regulated and research-intensive laboratory environments. Based on the proven Couette-flow–optimized piston displacement principle, the XLS+ delivers consistent volumetric delivery across its full operational range—from ultra-low volumes of 0.1 µL up to 20 mL—without requiring electronic actuation or external power. Its mechanical architecture integrates a low-friction, temperature-stable PVDF body, a calibrated spring-loaded plunger mechanism, and a patented LiteTouch™ Sealing (LTS) interface that ensures repeatable tip seating and minimal tip ejection force. Unlike conventional air-displacement pipettes, the XLS+ employs a minimized dead volume seal geometry and optimized internal airflow dynamics to reduce evaporation-induced error and thermal drift during extended use. The device complies with ISO 8655-2:2022 (volumetric performance) and supports traceable calibration workflows required under GLP, GMP, and FDA 21 CFR Part 11 frameworks.

Key Features

• LiteTouch™ Sealing (LTS) technology: Ensures uniform tip attachment force and reduces tip ejection load to just 0.6 kg—minimizing operator fatigue and repetitive strain injury (RSI) risk during high-throughput workflows.
• Ergonomic dual-hand design: Lightweight polymer construction (PVDF body), contoured grip zone, low-resistance plunger spring, and symmetrical volume adjustment dial enable comfortable, fatigue-resistant operation over prolonged shifts.
• Volume lock mechanism: Tamper-resistant, glove-compatible dial lock prevents accidental volume shift during benchtop transport or multi-step protocols.
• Autoclavable components: Front end (including O-rings and seals), tip ejector assembly, and removable sleeve withstand standard 121 °C, 20 min steam sterilization cycles without dimensional or functional degradation.
• Integrated passive RFID tag: Stores immutable service history, calibration dates, usage cycles, and maintenance logs—enabling audit-ready traceability and automated inventory management via optional RFID readers and Rainin Pipette Manager software.
• Silicone-damped tip ejection system: Absorbs mechanical shock at thumb contact point, enhancing user comfort and reducing long-term musculoskeletal stress.

Sample Compatibility & Compliance

The Pipet-Lite XLS+ is compatible with universal conical tips and LTS-certified tips across all 11 volume variants (0.1–10 µL, 2–200 µL, 10–1000 µL, 100–1000 µL, 0.5–5 mL, 1–10 mL, and 2–20 mL). Its chemically inert PVDF housing resists corrosion from common solvents including ethanol, isopropanol, acetone, and diluted acids/bases. All materials meet USP Class VI biocompatibility standards. The device conforms to ISO 8655-2:2022 for gravimetric accuracy verification and supports full validation per ASTM E2799-21 (Standard Guide for Pipette Calibration). Built-in RFID functionality satisfies data integrity requirements under FDA 21 CFR Part 11 (electronic records/signatures) and EU Annex 11 (computerized systems), enabling compliant GLP/GMP documentation without third-party add-ons.

Software & Data Management

Each XLS+ pipette contains a factory-programmed, write-once-read-many (WORM) passive RFID tag compliant with ISO/IEC 15693. When paired with the Rainin RFID Reader and Pipette Manager v4.x software, laboratories can automate calibration scheduling, generate electronic service logs, export CSV-formatted usage reports, and enforce role-based access control for instrument configuration. Audit trails include timestamps for every calibration event, technician ID, environmental conditions (if logged externally), and pass/fail status against defined tolerance limits. Data exports are compatible with LIMS integration via HL7 or RESTful API adapters. No cloud storage is required—the system operates fully on-premise to maintain data sovereignty and regulatory alignment.

Applications

The Pipet-Lite XLS+ serves critical roles in analytical QC/QA labs (e.g., pharmaceutical assay preparation, reference standard dilution), clinical diagnostics (serum/plasma aliquoting, ELISA setup), molecular biology (cDNA synthesis, qPCR master mix preparation), and academic research (cell culture media dispensing, enzyme kinetics assays). Its ultra-low volume capability (0.1 µL) supports nanoliter-scale applications such as microfluidic chip loading and single-cell RNA-seq library prep. The autoclavable front-end design makes it suitable for sterile technique workflows in BSL-2 containment areas and aseptic processing suites. Its mechanical reliability and absence of batteries or firmware make it ideal for field-deployable labs and resource-constrained settings where electronic dependency must be minimized.

FAQ

Is the Pipet-Lite XLS+ compatible with non-LTS tips?
Yes—universal-fit conical tips may be used, though LTS-certified tips are recommended to guarantee optimal sealing, accuracy, and tip ejection consistency.
Can the entire pipette be autoclaved?
No—only the front end (barrel, seals, and tip cone), tip ejector, and removable sleeve are autoclavable. The main body and internal spring mechanism must not be exposed to steam sterilization.
How is calibration traceability maintained?
Calibration events are recorded directly to the embedded RFID tag using Rainin’s certified calibration stations. Each entry includes date, technician ID, tolerance pass/fail result, and metrological uncertainty values.
Does the XLS+ require routine recalibration?
Per ISO 8655-5:2022, recalibration frequency depends on usage intensity, application criticality, and internal SOPs—but typical intervals range from 3 to 12 months, with documented verification before each high-value assay.
What does the ±0.6% accuracy specification represent?
This refers to maximum permissible error (MPE) at nominal volume under ISO 8655-2 test conditions (20 °C, distilled water, standard atmospheric pressure), expressed as percentage of set volume.