RAININ Pipet-One Manual Single-Channel Pipette

Overview

The RAININ Pipet-One Manual Single-Channel Pipette is a precision-engineered liquid handling instrument developed by METTLER TOLEDO’s RAININ division in Switzerland. Designed for high-frequency, repetitive pipetting tasks in regulated laboratory environments—including QC microbiology, molecular biology, clinical diagnostics, and pharmaceutical development—the Pipet-One operates on the air displacement principle, delivering volumetric accuracy and repeatability in strict accordance with ISO 8655–2 gravimetric performance standards. Its core architecture integrates low-force actuation mechanics and biomechanically validated ergonomics to mitigate operator fatigue and reduce the incidence of work-related musculoskeletal disorders (WMSDs), particularly repetitive strain injury (RSI) associated with prolonged manual pipetting.

Key Features

• Low-Force Actuation System: Patented lightweight aspiration and dispensing springs reduce piston stroke force by up to 25% compared to conventional manual pipettes—minimizing thumb and finger exertion during high-volume workflows.
• Ergonomic Gun-Style Body with Finger Hooks: Contoured grip geometry and integrated finger hooks enable semi-relaxed hand positioning; users maintain control without continuous gripping, allowing intrinsic muscle recovery between pipetting cycles.
• Silicone-Damped Tip Ejection Mechanism: Internally mounted silicone shock absorbers attenuate impact forces during tip ejection—reducing peak thumb load by >40% and enhancing long-term operator comfort.
• Textured, Chemical-Resistant Surface Finish: Micro-structured polypropylene housing provides consistent tactile feedback and slip resistance under wet or solvent-exposed conditions, supporting secure handling across diverse lab environments.
• Full-Autoclavability: All models are certified for full-assembly autoclaving at 121°C for 20 minutes without disassembly—ensuring compliance with ISO 13485 and FDA 21 CFR Part 820 requirements for device reprocessing in GMP settings.
• Modular Tip Ejector with Positive-Lock Retention: Quick-release ejector button enables one-touch tip removal; integrated mechanical lock prevents accidental detachment during transport or storage.

Sample Compatibility & Compliance

The Pipet-One series accommodates standard conical polypropylene tips (including RAININ LTS and universal-fit formats) across eight calibrated volume ranges—from 0.1 µL to 10 mL—each individually verified per ISO 8655–2 tolerance limits. All units undergo factory calibration traceable to NIST-certified mass standards and include a Certificate of Conformance compliant with ISO/IEC 17025 documentation requirements. The pipette meets EN ISO 10535–1 ergonomic design criteria for hand tools and supports audit-ready documentation for GLP, GMP, and CLIA-regulated laboratories. Tip compatibility extends to low-retention, filtered, and sterile barrier tips—enabling applications ranging from qPCR master mix preparation to cytotoxic compound handling.

Software & Data Management

While the Pipet-One is a fully manual instrument, its design supports digital workflow integration through RAININ’s Pipette Tracker software platform (sold separately). When registered via serial number, each unit generates an electronic calibration history log—including date-stamped calibration events, technician ID, environmental conditions, and deviation reports—exportable as PDF or CSV for internal QA review or regulatory submission. Audit trails comply with FDA 21 CFR Part 11 requirements when deployed with validated electronic signature modules. Optional RFID-enabled base stations allow automated usage logging and preventive maintenance scheduling based on actuation cycle counts.

Applications

The Pipet-One is routinely deployed in applications demanding both volumetric fidelity and operator sustainability: quantitative nucleic acid dilution in NGS library prep; serial dilution of reference standards in analytical method validation; cell suspension transfer in primary culture workflows; formulation sampling in sterile fill-finish environments; and reagent dispensing in ELISA and lateral flow assay development. Its reduced actuation force and stable tip seal integrity make it especially suitable for viscous solutions (e.g., glycerol-containing buffers), high-salt matrices, and temperature-sensitive samples where thermal drift or inconsistent plunger pressure may compromise accuracy.

FAQ

Is the Pipet-One compatible with non-RAININ tips?
Yes—mechanically compatible with all industry-standard conical tips meeting ISO 8655 dimensional specifications; optimal performance is achieved with RAININ LTS or Filter Tips.
Can the Pipet-One be calibrated in-house?
Yes—calibration is performed gravimetrically using certified weights and distilled water per ISO 8655–2; RAININ provides detailed SOPs and traceable calibration kits for qualified personnel.
What is the recommended recalibration frequency?
Annual calibration is advised under normal use; more frequent verification (e.g., quarterly) is recommended in high-throughput or regulated environments per ISO/IEC 17025 Clause 7.7.
Does the Pipet-One support tip ejection with gloves?
Yes—the large-diameter ejection button and tactile surface texture ensure reliable operation with nitrile, latex, and powder-free laboratory gloves.
Are service manuals and spare parts available internationally?
Yes—RAININ maintains global technical support centers with authorized service partners; OEM replacement components (piston assemblies, seals, ejector modules) are available with documented lot traceability.