Sartorius arium® advance EDI Ultra-Pure Water System
| Brand | Sartorius |
|---|---|
| Origin | Germany |
| Model | arium® advance EDI |
| Purified Water Grade | ASTM Type II / ISO 3696 Grade 2 |
| Maximum Flow Rate | 10 L/h |
| Resistivity (at 25 °C) | 5–15 MΩ·cm |
| Heavy Metals & Soluble Silica | < 0.1 ppm |
| Total Organic Carbon (TOC) | < 30 ppb |
| Particles (>0.1 µm) | < 1 particle/mL |
| Ion Removal Efficiency (EDI-based) | >99% for monovalent ions |
| Organic Removal (MW >300 Da) | >99% |
| Microbial Reduction | >99% (via integrated 0.22 µm final filter) |
| Storage | Integrated sealed bag-in-box reservoir (prevents ambient recontamination) |
Overview
The Sartorius arium® advance EDI Ultra-Pure Water System is an engineered solution for continuous, on-demand production of high-purity Type II laboratory water in compliance with ASTM D1193-20 and ISO 3696:1987 standards. Utilizing electrodeionization (EDI) as the core purification technology—combined with dual-stage reverse osmosis pre-treatment, activated carbon adsorption, and final 0.22 µm membrane filtration—the system delivers consistent water quality at up to 10 L/h. Unlike conventional ion-exchange or distillation-based systems, the arium® advance EDI eliminates the need for chemical regeneration or frequent cartridge replacement, reducing operational downtime and long-term cost of ownership. Its closed-loop architecture, including a sterile, single-use bag-in-box storage reservoir, prevents post-purification contamination from airborne particles, microbial ingress, or ambient CO₂ absorption—critical for maintaining stable resistivity and low TOC over time.
Key Features
- Intelligent iJust™ water optimization algorithm dynamically adjusts EDI current and flow distribution based on real-time feedwater carbonate hardness (CaCO₃) and dissolved CO₂ levels—maximizing ion removal efficiency while conserving water and energy.
- 10.1-inch capacitive touchscreen interface with glove-compatible operation, hierarchical navigation, and context-sensitive help—designed for rapid training and error-free daily use in high-throughput labs.
- Modular installation flexibility: benchtop, wall-mounted, or under-bench integrated configuration—supporting space-constrained environments without compromising service accessibility.
- Hermetically sealed, disposable bag-in-box water reservoir (available in 30 L and 60 L variants) eliminates headspace exposure, ensuring TOC stability (<30 ppb) and particulate integrity (0.1 µm) throughout storage and dispensing.
- Integrated conductivity, TOC, and pressure sensors provide continuous monitoring; all critical parameters are logged with timestamped audit trails compliant with GLP and FDA 21 CFR Part 11 requirements when paired with Sartorius LabX® software.
Sample Compatibility & Compliance
The arium® advance EDI is validated for preparation of reagents and solutions used in analytical chemistry (e.g., HPLC mobile phase dilution, AAS standard preparation), microbiology (media formulation, buffer preparation), immunology (ELISA/RIA assay diluents), histology (staining solutions), and general lab support (autoclave feed, glassware rinsing, water baths). It meets or exceeds performance criteria specified in ASTM Type II, ISO 3696 Grade 2, and CLSI EP22-A guidelines for non-critical applications requiring low ionic and organic contamination. The system’s design supports trace-metal-sensitive workflows due to its stainless-steel-free fluid path (PEEK and PP components only) and absence of leachable silicates or heavy metals from internal media.
Software & Data Management
The embedded iJust™ firmware enables predictive maintenance alerts (e.g., RO membrane fouling index, EDI stack voltage drift) and automatic calibration logging. When connected to Sartorius LabX® Laboratory Software, the system provides full electronic record management—including user authentication, role-based access control, digital signature capability, and exportable CSV/PDF reports for regulatory audits. All water quality events (e.g., resistivity excursions, TOC spikes, filter saturation warnings) are time-stamped, linked to operator ID, and retained for ≥36 months per internal memory or network backup.
Applications
- Preparation of buffers and standards for UV-Vis spectrophotometry, titration, and ion chromatography.
- Rinsing of precision glassware and pipettes prior to trace-element analysis (ICP-MS, ICP-OES).
- Feed water for autoclaves, steam generators, and humidifiers where silica scaling must be minimized.
- Dilution of cell culture media and ELISA substrates where endotoxin-free water is not required but low TOC and ionic residue are essential.
- Support of automated analyzers (e.g., clinical chemistry platforms) requiring stable, low-conductivity feed water.
FAQ
What is the expected service life of the EDI module under typical lab conditions?
Under recommended feedwater specifications (hardness <100 ppm CaCO₃, SDI 95% ion removal efficiency for ≥24 months with routine preventive maintenance.
Can the system be integrated into a central purified water network?
Yes—the arium® advance EDI supports loop integration via optional 0.22 µm recirculation filter and flow-controlled booster pump (accessory kit available).
Is the bag-in-box reservoir certified for USP water storage?
The reservoir meets ISO 11663:2015 for pharmaceutical-grade water containment and is compatible with USP storage principles when used within validated hold times (≤72 h at ambient temperature).
Does the system comply with EU Medical Device Regulation (MDR) or IVDR requirements?
While classified as Class I laboratory equipment under MDR Annex VIII, the arium® advance EDI carries CE marking per Directive 2014/30/EU (EMC) and 2014/35/EU (LVD); full IVDR applicability depends on end-use configuration and risk assessment by the end user.
How frequently must the pre-filtration cartridges be replaced?
Carbon and sediment filters require replacement every 6–12 months depending on feedwater quality; RO membrane replacement interval is typically 2–3 years, monitored via differential pressure and rejection rate tracking.
