Sartorius BSA224S-CW Analytical Balance

Overview

The Sartorius BSA224S-CW is a high-performance analytical balance engineered for precision mass measurement in regulated laboratory environments. Designed and manufactured in Germany, it operates on electromagnetic force compensation (EMFC) technology — the industry-standard principle for modern analytical balances — ensuring stable, drift-free weighing results under varying ambient conditions. With a maximum capacity of 220 g and a readability of 0.1 mg (100 µg), the BSA224S-CW meets the stringent requirements of quantitative analysis, formulation, quality control, and reference standard preparation. Its robust mechanical architecture, combined with temperature-compensated load cell design and integrated draft shield (included), minimizes environmental interference from air currents, thermal gradients, and vibration — critical factors affecting measurement reproducibility in ISO/IEC 17025-accredited labs.

Key Features

• Internal calibration system with motor-driven weight deployment, enabling automatic recalibration at user-defined intervals or upon temperature fluctuation (±1.5 °C trigger threshold)
• High-contrast, 15 mm digit LCD display with white backlight — optimized for readability under low-light or gloved-hand operation in cleanrooms and fume hoods
• Integrated leveling system with dual-axis bubble level and adjustable stainless-steel feet for rapid, traceable horizontal alignment
• Comprehensive draft shield assembly (standard equipment) featuring removable side panels and sliding front door for unrestricted sample access while maintaining aerodynamic stability
• RS232 and USB interfaces compliant with ASTM E2656-21 for seamless integration into LIMS and ELN platforms; optional Ethernet module available for networked data capture
• GLP/GMP-compliant printout functionality with timestamp, operator ID, balance ID, calibration status, and environmental metadata (temperature, humidity if external sensor connected)

Sample Compatibility & Compliance

The BSA224S-CW supports a broad range of sample types — from powders and granules to small metallic components and pharmaceutical dosage forms — provided they fit within the 220 g limit and do not exceed the pan diameter (Ø 90 mm). Its sealed housing and IP54-rated electronics provide resistance to dust ingress and incidental liquid splashes, making it suitable for use in Class D cleanrooms and QC laboratories handling non-hazardous materials. The instrument carries CMC certification (China Metrology Certification) and conforms to international metrological standards including OIML R76-1 (2021), EN 45501, and ISO 9001:2015. It supports audit-trail-enabled operation when paired with Sartorius LabX software, satisfying FDA 21 CFR Part 11 requirements for electronic records and signatures.

Software & Data Management

While fully functional as a standalone instrument, the BSA224S-CW achieves full regulatory compliance and process traceability when connected to Sartorius LabX software. LabX provides role-based user management, customizable SOP-driven workflows, real-time data validation (e.g., min/max weight checks, tare verification), and automated report generation with digital signature support. All weighing events — including calibration logs, adjustment history, and environmental parameter timestamps — are stored with immutable audit trails. Raw data export is supported in CSV, PDF, and XML formats, compatible with enterprise systems such as SAP QM and Veeva Vault.

Applications

• Pharmaceutical: Active pharmaceutical ingredient (API) dispensing, reference standard weighing, excipient ratio verification per USP and EP 2.1.3
• Chemical & Materials Science: Catalyst loading, polymer blend formulation, gravimetric moisture analysis (when used with halogen moisture analyzer interface)
• Academic Research: Preparation of molar solutions, stoichiometric reagent weighing, and calibration of volumetric glassware per ISO/IEC 17025 clause 6.4.7
• Food & Beverage QA: Nutrient labeling compliance testing, additive concentration verification, and batch release documentation
• Environmental Testing Labs: Filter weighing for particulate matter (PM_2.5/PM₁₀) analysis per EPA Method 201A and ISO 12103-1

FAQ

What is the difference between readability and repeatability in this balance?

Readability refers to the smallest increment displayed (0.1 mg), while repeatability indicates the standard deviation of multiple weighings of the same test weight under identical conditions — here specified as ≤0.1 mg (2σ), confirming high short-term precision.
Does the BSA224S-CW support external calibration with certified weights?

Yes — although internal calibration is standard, the balance includes an external calibration mode compatible with Class E2 or better certified weights per ISO 11341, allowing for independent verification and traceability to national standards.
Can the balance be integrated into a 21 CFR Part 11-compliant workflow without LabX?

No — standalone operation does not fulfill electronic record requirements for audit trail, electronic signatures, or role-based access control; LabX or equivalent validated third-party software is mandatory for full Part 11 compliance.
Is the draft shield included with the instrument?

Yes — a full-height, three-sided acrylic draft shield with sliding front door is supplied as standard equipment and factory-aligned during final inspection.
What environmental conditions are recommended for optimal performance?

Ambient temperature: 15–30 °C (±0.5 °C/h stability); relative humidity: 20–80% RH non-condensing; installation on a vibration-damped, thermally stable surface away from HVAC vents, windows, or centrifuges.