Scientz SCIENTZ-10N/A Standard Benchtop Freeze Dryer
| Brand | Scientz |
|---|---|
| Origin | Zhejiang, China |
| Model | SCIENTZ-10N/A |
| Instrument Type | Standard Shelf-Type Freeze Dryer |
| Application Scope | Laboratory Use |
| Lyophilization Area | 0.12 m² |
| Ultimate Vacuum (Empty Chamber) | ≤5 Pa |
| Main Unit Dimensions | 610(L) × 482(W) × 455(H) mm + 440 mm (Cold Trap Height) |
| Condenser Capacity | 3 kg/batch |
| Empty-Chamber Condenser Temperature | ≤−56 °C (standard) |
| Power Supply | 220 V, 50 Hz |
| Rated Power | 0.95 kW (standard) |
| Ambient Operating Temperature | ≤25 °C |
| Net Weight | 55 kg (standard) |
Overview
The Scientz SCIENTZ-10N/A is a compact, benchtop shelf-type freeze dryer engineered for precision lyophilization in academic, governmental, and early-stage biopharmaceutical laboratories. It operates on the fundamental principle of sublimation—removing water from frozen samples under deep vacuum while maintaining sample integrity through low-temperature condensation. In this process, ice transitions directly from solid to vapor without passing through the liquid phase, preserving labile biological structures such as proteins, nucleic acids, enzymes, vaccines, and microbial cultures. The unit features a stainless steel shelf system with uniform heat transfer, a high-efficiency condenser cooled by a sealed, imported compressor, and a fully integrated vacuum control architecture. Designed for reproducible batch processing of up to 3 kg of frozen material per cycle, the SCIENTZ-10N/A delivers consistent drying performance across diverse sample matrices—including aqueous solutions, tissue homogenates, cell suspensions, and pharmaceutical formulations—while occupying minimal floor space (610 × 482 × 455 mm main unit footprint).
Key Features
- Compact benchtop design optimized for space-constrained laboratories; total height includes vertical cold trap extension (440 mm)
- Imported hermetic compressor system ensuring stable condenser temperatures ≤−56 °C (empty), with optional −80 °C configuration for low-eutectic-point materials
- 7-inch true-color capacitive touchscreen interface with industrial-grade embedded OS for responsive operation and real-time parameter monitoring (condenser temp, chamber pressure, shelf temp, elapsed time)
- Automated vacuum pump control logic: pump activation delayed until condenser reaches preset temperature, extending pump service life and reducing oil backstreaming risk
- One-piece transparent polycarbonate drying chamber—optically clear, corrosion-resistant, seamless, and rated for long-term vacuum integrity up to 5 Pa
- Integrated inert gas purge valve (N₂ or Ar compatible) for oxygen-sensitive samples and sterile processing environments
- Auto-save functionality for complete lyophilization profiles; data exportable via USB to external PCs for GLP-compliant documentation and audit trail generation
Sample Compatibility & Compliance
The SCIENTZ-10N/A accommodates a broad spectrum of laboratory-scale samples: microbiological cultures (bacteria, yeast, viruses), mammalian and insect cell pellets, serum, plasma, monoclonal antibodies, oligonucleotides, plant extracts, food matrices (fruits, vegetables, meat), environmental specimens (soil, sludge), and polymer/nanomaterial dispersions. Its 0.12 m² shelf area supports standard Ø200 mm trays (4 trays included) with 70 mm vertical spacing, enabling multi-layer drying without cross-contamination. The system meets general requirements for ISO 22000, USP , and ASTM F2375–04 (Standard Guide for Validation of Freeze Drying Processes). While not pre-certified for GMP manufacturing, its data logging, parameter traceability, and configurable alarm thresholds support qualification under FDA 21 CFR Part 11 when deployed with validated software protocols and procedural SOPs.
Software & Data Management
The embedded control firmware records all critical process variables at user-defined intervals (default: 10 s), generating timestamped CSV files containing condenser temperature, chamber pressure, shelf setpoint/actual, and cycle stage metadata. Up to 100 freeze-drying protocols can be stored internally; additional methods may be loaded via USB. Exported datasets are compatible with common analytical platforms (e.g., MATLAB, Python pandas, Excel) for post-run analysis of drying kinetics, primary drying endpoint detection, and shelf heat transfer coefficient modeling. Optional PC-based upper-level software provides advanced visualization tools—including real-time curve overlay, deviation alerts, and comparative batch trending—supporting method development and regulatory documentation workflows aligned with ALCOA+ principles.
Applications
This freeze dryer serves core functions across multiple research and quality control domains: stabilization of thermolabile biologics (e.g., lyophilized ELISA reagents, diagnostic kits, reference standards); preparation of archival biospecimens (tissue sections, blood fractions, bacterial stocks); formulation development for parenteral products (vaccines, interferons, enzyme therapeutics); pretreatment of environmental and food samples prior to elemental or organic residue analysis; and structural preservation of nanomaterials and porous scaffolds where solvent removal must avoid capillary collapse. Its adaptability to varied container formats—including vials (Φ12/16/22 mm), flask adapters, and custom trays—makes it suitable for both exploratory screening and standardized QC testing in university core facilities, public health labs, and contract research organizations.
FAQ
What is the maximum batch capacity for aqueous solutions?
The SCIENTZ-10N/A supports up to 1.5 L of solution per batch when using standard Ø200 mm trays, corresponding to ~3 kg total ice load under optimal freezing conditions.
Can the system operate continuously over multiple cycles without maintenance?
Yes—provided ambient temperature remains ≤25 °C and condenser defrosting is performed between batches (manual or optional electric defrost), the unit is rated for uninterrupted operation across consecutive lyophilization runs.
Is the vacuum system compatible with oil-free pumping alternatives?
While configured for use with standard two-stage rotary vane pumps (oil-lubricated), the inlet port accepts alternative vacuum sources including dry scroll or diaphragm pumps; however, ultimate vacuum performance ≤5 Pa requires appropriate pump sizing and optional oil mist filter installation.
Does the controller support programmable ramp-hold drying profiles?
Yes—the touchscreen interface allows full customization of shelf temperature ramps, hold durations, and pressure modulation steps, enabling optimization for complex multi-phase drying processes.
What certifications does the instrument carry for international shipment?
The SCIENTZ-10N/A complies with CE marking requirements (EMC Directive 2014/30/EU and Low Voltage Directive 2014/35/EU); RoHS and REACH declarations are available upon request for customs clearance and institutional procurement compliance.
