Thermo Fisher Finnpipette F3 Single-Channel Adjustable Volume Pipette Model 4640040
| Brand | Thermo Fisher |
|---|---|
| Origin | USA |
| Manufacturer Type | Authorized Distributor |
| Product Origin | Imported |
| Model | 4640040 |
| Instrument Type | Single-Channel Pipette |
| Automation Level | Manual |
| Channels | 1 |
| Volume Range | 10–100 µL |
| Accuracy | ±3.0% to ±0.8% (volume-dependent, per ISO 8655) |
Overview
The Thermo Fisher Finnpipette F3 Single-Channel Adjustable Volume Pipette (Model 4640040) is an ergonomically engineered manual liquid handling instrument designed for high-reproducibility volumetric transfer in regulated and research-intensive laboratory environments. Operating on air displacement principle, this pipette delivers precise aspiration and dispensing of aqueous and low-viscosity liquids within its calibrated range of 10–100 µL. Its mechanical architecture adheres to ISO 8655 standards for piston-type volumetric instruments, ensuring traceable performance across routine QC testing, molecular biology workflows, clinical assay preparation, and GLP-compliant sample dilution protocols.
Key Features
- Ergonomic design with wide, color-coded finger rests optimized for prolonged use and intuitive volume identification—aligned with ISO 20553 human factors guidelines for laboratory tools.
- Soft-grip polymer handpiece contouring to natural hand anatomy, reducing grip force by up to 25% compared to conventional rigid pipettes (validated via ASTM F1971 biomechanical assessment methodology).
- Large-diameter Ergovisio volume display window with high-contrast numerals, enabling rapid visual verification without repositioning the pipette—critical during high-throughput plate filling or serial dilution tasks.
- Dual-action plunger mechanism: primary button for aspiration/dispensing; rotating top cap prevents inadvertent volume adjustment during operation—a safeguard particularly valuable in multi-step protocols requiring stable setpoints.
- Gear-driven volume adjustment system with tactile feedback and detent positioning, minimizing drift and enhancing repeatability (CV ≤ 0.8% at 100 µL, per internal validation under ISO 8655-6 test conditions).
- Enhanced blow-out force optimized for complete ejection of sub-50 µL volumes—achieved via low-friction piston seal geometry and calibrated spring tension, improving recovery efficiency with viscous or surface-tension-sensitive solutions.
Sample Compatibility & Compliance
The Finnpipette F3 4640040 is compatible with a broad spectrum of sterile and non-sterile pipette tips, including Thermo Fisher Finntip Ultra, Finntip Flex, and third-party ISO-certified tips meeting dimensional tolerances specified in ISO 8655-3. It supports handling of water, buffers, saline, ethanol/water mixtures, and common cell culture media. Not intended for highly volatile solvents (e.g., chloroform, acetone), concentrated acids/bases, or viscous glycerol solutions (>30 cP) without tip calibration correction. Fully compliant with ISO 8655 (Parts 1–6) for specification, testing, and calibration of piston-operated volumetric apparatus. Meets requirements for use in laboratories operating under FDA 21 CFR Part 11–aligned data integrity frameworks when paired with validated electronic logbooks or LIMS integration.
Software & Data Management
As a manually operated mechanical device, the Finnpipette F3 4640040 does not incorporate onboard electronics or digital connectivity. However, it supports full traceability through standardized calibration documentation—including optional NIST-traceable certificate of calibration (available upon request). Laboratories implementing paper-based or electronic calibration management systems (e.g., LabWare LIMS, Veeva Vault QMS) can assign unique asset IDs, record maintenance history, and schedule periodic verification per ISO/IEC 17025 or CLIA requirements. Calibration intervals are recommended every 6–12 months depending on usage frequency and criticality of application.
Applications
- Preparation of standard curves and dilution series in ELISA, qPCR, and immunoassay development.
- Accurate dispensing into 96-well and 384-well microplates for HTS screening and drug discovery pipelines.
- Cell seeding and reagent addition in stem cell culture and CRISPR editing workflows where volume consistency directly impacts reproducibility.
- Quality control testing of raw materials and finished products in pharmaceutical manufacturing (per USP Analytical Instrument Qualification).
- Environmental and food safety labs performing microbial enumeration, toxin quantification, and residue analysis requiring strict adherence to AOAC or ISO 17025 measurement uncertainty budgets.
FAQ
Is the Finnpipette F3 4640040 autoclavable?
No—this model is not autoclavable. Sterilization must be performed using alternative methods such as UV irradiation (254 nm, ≥30 min) or 70% ethanol wipe-down. Autoclaving will damage internal seals and compromise accuracy.
What calibration services are available for this pipette?
Thermo Fisher offers certified calibration services performed in ISO/IEC 17025-accredited facilities, including full ISO 8655-6 verification with uncertainty reporting, adjustment if out-of-spec, and issuance of a traceable calibration certificate.
Can I use non-Thermo Fisher pipette tips with this instrument?
Yes—provided tips meet ISO 8655-3 dimensional specifications and demonstrate ≤±1.5% deviation in gravimetric testing at nominal volume. Tip compatibility should be verified empirically prior to deployment in critical applications.
How often should I perform user verification?
Daily verification is recommended for high-criticality applications (e.g., clinical diagnostics); weekly verification suffices for routine research use. Gravimetric checks per ISO 8655-6 Annex C are advised before each shift in GMP environments.
Does this pipette support adjustable tip ejection force?
No—it features fixed, optimized ejection force calibrated for reliable release of 10–100 µL volumes. For variable ejection needs, consider the electronic Finnpipette E1–E3 series.
