YSEI SHH-150L Biochemical Incubator

Overview

The YSEI SHH-150L Biochemical Incubator is a precision-engineered, forced-air, compressor-cooled environmental chamber designed for stable, long-term cultivation and maintenance of microorganisms, bacterial cultures, cell lines, plant tissues, and seedlings under tightly controlled thermal conditions. Operating on the principle of active air circulation via a centrifugal fan and dual-channel PID-controlled heating/cooling system, it delivers high thermal uniformity (±1 °C) across its 150 L stainless-steel inner chamber—critical for reproducible biological assays, stability studies, and routine microbiological work. Unlike natural convection incubators, the SHH-150L’s forced convection architecture ensures rapid temperature recovery after door opening and minimizes vertical/horizontal gradients—particularly essential for multi-tier shelving configurations and sensitive low-temperature applications (e.g., psychrophilic culture at 4 °C). Its design adheres to GB/T 28851–2012, the Chinese national standard for biochemical incubators, and incorporates engineering safeguards aligned with international good laboratory practice (GLP) expectations for equipment qualification and data integrity.

Key Features

• Compressor-based refrigeration system enabling precise sub-ambient operation from 4 °C to 50 °C with consistent thermal stability
• Forced convection airflow architecture with adjustable fan speed, ensuring uniform temperature distribution and minimized stratification
• Dual independent temperature sensors (working + backup) with real-time deviation monitoring and automatic fault logging
• Dedicated over-temperature protection circuit isolated from the main control loop—mechanically triggered cutoff at user-defined threshold
• Integrated thermal printer supporting configurable print intervals (1–60 min), generating time-stamped, tamper-evident paper records compliant with audit trail requirements
• Embedded SMS alarm module with programmable thresholds for temperature deviation, power failure, and compressor fault—supports centralized fleet management across up to 30 units
• Low-noise motor and acoustic insulation yielding operational sound pressure levels <55 dB(A) at 1 m—suitable for shared lab environments
• Energy-optimized thermal insulation (high-density polyurethane foam, ≥80 mm thickness) and intelligent compressor cycling to reduce standby power consumption

Sample Compatibility & Compliance

The SHH-150L accommodates standard microbiological consumables including Petri dishes (up to 150 mm), test tubes (16 × 150 mm), Erlenmeyer flasks (up to 2 L), and multi-well plates (6–96-well), with three adjustable stainless-steel shelves (load capacity: 15 kg/shelf). Its chamber surface finish meets ISO 14644-1 Class 8 (100,000) cleanroom compatibility requirements when operated in filtered-air mode (optional HEPA retrofit available). The unit supports IQ/OQ documentation packages—including installation verification checklists, operational performance tests (e.g., temperature mapping per ISO 14644-3 Annex B), and calibration certificate templates traceable to NIM (National Institute of Metrology, China). While not pre-certified to FDA 21 CFR Part 11, its data logging architecture (timestamped binary logs + printed hardcopy) enables validation pathways for regulated environments under GLP or GMP frameworks.

Software & Data Management

The embedded controller features a 4.3-inch capacitive touchscreen interface with multilingual support (English, Chinese, Spanish). All temperature setpoints, alarms, print cycles, and SMS parameters are configurable via intuitive menus. Internal non-volatile memory stores ≥30 days of 1-minute interval temperature history (time, setpoint, actual value, deviation). Data export is supported via USB 2.0 port (CSV format) for post-processing in Excel or statistical software (e.g., JMP, Minitab). Remote access is enabled through TCP/IP Ethernet connectivity using Modbus RTU/TCP protocol—allowing integration into building management systems (BMS) or centralized lab monitoring platforms (e.g., LabVantage, Thermo Fisher SampleManager). Audit trail functionality includes operator ID logging (via optional RFID badge reader), event timestamps, and immutable record of all parameter changes.

Applications

• Bacterial and fungal culture maintenance (e.g., E. coli, S. aureus, C. albicans) at defined physiological temperatures
• Plant tissue culture and seed germination studies requiring precise low-temperature stratification (4–10 °C)
• Enzyme activity assays and protein stability testing under controlled thermal stress
• Environmental simulation for biodegradation studies and ecotoxicology screening
• QC/QA stability chambers for pharmaceutical excipients and diagnostic reagents (ICH Q1A–Q1E compliant protocols achievable with mapping)
• Academic teaching labs conducting microbial growth kinetics and inhibition experiments

FAQ

Does the SHH-150L support humidity control?
No—this model is a temperature-only incubator. Humidity control requires the optional SHH-150L-H variant with integrated ultrasonic humidifier and condensate management.
Can the built-in printer generate PDF reports directly?
No—the thermal printer produces physical paper records only. Digital CSV exports via USB support downstream PDF generation in external software.
Is the SMS alarm system compatible with international carriers?
Yes—provided local SIM card activation and GSM band compatibility (quad-band 850/900/1800/1900 MHz); configuration requires APN settings per carrier.
What validation documentation is included with purchase?
Standard delivery includes IQ/OQ templates, factory calibration report (NIST-traceable reference thermometer), and GB/T 28851–2012 compliance statement. Full execution services are available as a billable option.
How is temperature uniformity verified during OQ?
Per ISO 14644-3 Annex B, a minimum of 9 thermocouples (3×3 grid) are placed at defined locations (center, corners, mid-height) across three load configurations (empty, 50% loaded, fully loaded) over 24 hours.