YSEI SHH-250L Biochemical Incubator

Overview

The YSEI SHH-250L Biochemical Incubator is a precision-engineered, microprocessor-controlled environmental chamber designed for stable, long-term cultivation and preservation of bacteria, fungi, yeast, mammalian cell lines, and plant tissues under tightly regulated thermal conditions. Based on forced-air convection and compressor-driven refrigeration, the system maintains uniform temperature distribution across its 250-liter working volume—critical for reproducible microbiological assays, seed germination studies, enzymatic activity profiling, and stability testing in academic, pharmaceutical, and industrial life science laboratories. Its operational range of 4–50 °C supports both mesophilic and psychrotrophic culture protocols, while compliance with GB/T 28851–2012 ensures alignment with nationally recognized performance and safety benchmarks for biochemical incubation equipment.

Key Features

• Compressor-based refrigeration system enabling precise sub-ambient temperature control down to 4 °C, with rapid thermal recovery after door opening
• Forced-air circulation architecture with rear-mounted fan and optimized baffle design to achieve ±1 °C temperature uniformity throughout the chamber
• Dual independent temperature sensors (working chamber + overtemperature cutoff) linked to an isolated overtemperature protection circuit for fail-safe operation
• Integrated thermal printer supporting configurable print intervals (e.g., every 1, 5, or 30 minutes) for real-time hard-copy record generation compliant with GLP documentation requirements
• Multi-layer data logging: continuous storage of time-stamped temperature values with up to 30 days of onboard history; exportable via USB to CSV format for audit-ready traceability
• Remote monitoring and centralized management capability—up to 30 units can be networked via Ethernet or Wi-Fi to a single host PC using YSEI’s proprietary LabLink™ software platform
• Low-noise operation (<52 dB[A] at 1 m) achieved through vibration-dampened compressor mounting and acoustic insulation of internal ductwork
• Energy-efficient design meeting Class B energy consumption standards per GB 12021.2, reducing operational cost without compromising thermal stability

Sample Compatibility & Compliance

The SHH-250L accommodates standard laboratory vessels including Petri dishes, multi-well plates (6–96-well), Erlenmeyer flasks (up to 2 L), tissue culture flasks, and glass jars—compatible with both sterile and non-sterile workflows. Internal chamber construction uses electropolished stainless steel (SUS304) with rounded corners to minimize contamination risk and facilitate cleaning. The unit supports IQ/OQ validation packages aligned with ISO/IEC 17025 and FDA 21 CFR Part 11 requirements—including electronic signature support, user access levels (admin/operator), and full audit trail functionality for all parameter changes and alarm events. It is suitable for use in GMP-compliant environments when integrated into documented quality systems.

Software & Data Management

LabLink™ software provides secure, role-based remote access for configuration, real-time monitoring, historical trend analysis, and alarm acknowledgment. All logged data are timestamped with UTC synchronization and stored with cryptographic integrity checks. The system supports automated report generation in PDF format, including min/max/mean statistics, deviation alerts, and pass/fail status against user-defined acceptance criteria. Data export complies with ALCOA+ principles (Attributable, Legible, Contemporaneous, Original, Accurate, Complete, Consistent, Enduring, Available) for regulatory submissions. Optional integration with LIMS platforms is available via RESTful API or OPC UA protocol.

Applications

• Bacterial growth kinetics and antibiotic susceptibility testing (AST)
• Fungal sporulation and mycelial expansion studies
• Plant tissue culture and callus induction under controlled photoperiod-independent conditions
• Enzyme stability assessment during accelerated shelf-life testing
• Environmental simulation for ecotoxicology and biodegradation assays
• Long-term strain archiving of clinical isolates and reference cultures
• QC/QA incubation for media sterility validation and endotoxin testing

FAQ

Does the SHH-250L support humidity control?
No—this model is a temperature-controlled biochemical incubator only. Humidity regulation is not integrated; for combined temp/humidity applications, consider the YSEI SHH-H series.
Can the built-in printer generate ISO 17025-compliant calibration records?
Yes—the printer outputs traceable, time-stamped records that may serve as supplementary evidence during accreditation audits when used alongside certified external thermometers and validated procedures.
Is remote firmware update supported?
Firmware updates require local USB connection and administrative credentials; remote OTA updates are not implemented for security reasons per IEC 62443-3-3 guidelines.
What validation documentation is included with purchase?
Each unit ships with a Factory Acceptance Test (FAT) report, IQ/OQ templates, and a Certificate of Conformance to GB/T 28851–2012. Full validation execution services are available upon request.
How many users can simultaneously access the LabLink™ software interface?
LabLink™ supports concurrent access by up to five authenticated users with configurable permission tiers (view-only, operator, administrator).