YSEI SHH-500L Biochemical Incubator

Overview

The YSEI SHH-500L Biochemical Incubator is a precision-engineered, forced-air laboratory incubator designed for stable, long-term cultivation of microorganisms, bacterial cultures, fungal strains, and plant tissue under tightly controlled thermal conditions. Built upon the principles of convective heat transfer and closed-loop PID temperature regulation, the SHH-500L delivers high reproducibility in temperature maintenance across its entire 500 L working chamber. Its compressor-based cooling system enables active thermal management down to 15 °C — a critical capability for low-temperature biochemical assays, psychrophilic organism studies, and stability testing protocols requiring sub-ambient operation. The unit conforms to GB/T 28851–2012, the People’s Republic of China national standard for biochemical incubators, and incorporates structural and functional design elements aligned with international good laboratory practice (GLP) expectations for environmental control equipment.

Key Features

• Forced convection airflow system with dual-directional fan and optimized baffle geometry ensures uniform temperature distribution (±1 °C) throughout the 500 L chamber, validated per ISO 14644-1 air uniformity methodology.
• Compressor-driven refrigeration module provides precise sub-ambient temperature control from 15 °C to 50 °C, eliminating reliance on external chillers or ice-based cooling methods.
• Integrated thermal line printer supports real-time, tamper-evident hardcopy recording of temperature data; print interval configurable from 1 minute to 24 hours.
• Dual-layer safety architecture includes independent over-temperature cut-off circuitry (hardware-redundant), compressor overload protection, and programmable alarm thresholds for deviation events.
• SMS alert system interfaces with cellular networks to transmit immediate notifications upon power interruption, temperature excursion (>±1.5 °C), or door-open duration exceeding user-defined limits — supporting multi-unit fleet monitoring.
• Ethernet-enabled controller allows centralized supervision via local network or secure internet connection; up to 30 SHH-series units can be managed simultaneously through a single web-based interface.
• Energy-optimized insulation (high-density polyurethane foam, 80 mm thick) and brushless DC fan motor reduce power consumption by ≥22% compared to conventional incubators in the same class.

Sample Compatibility & Compliance

The SHH-500L accommodates standard microbiological and botanical sample formats including Petri dishes (up to 150 mm), culture flasks (up to 5 L), multi-well plates, and plant growth trays. Its interior chamber is constructed from electropolished 304 stainless steel with rounded corners and seamless welds, facilitating cleaning validation and minimizing microbial retention points. The unit supports compliance workflows for regulated environments: full IQ/OQ documentation packages are available upon request, including traceable calibration records, alarm response verification, and temperature mapping reports (per ASTM E2297). While not pre-certified to FDA 21 CFR Part 11, the system’s audit trail functionality (timestamped parameter changes, user login logs, and event history export) provides foundational infrastructure for electronic record integrity in GMP/GLP settings.

Software & Data Management

The embedded controller runs a deterministic real-time OS with non-volatile memory for storing >12 months of 1-minute-interval temperature logs. Data export is supported via USB flash drive (CSV format) or network transfer (FTP/SFTP). The optional YSEI LabLink™ software suite enables remote configuration, live dashboard visualization, automated report generation (PDF/Excel), and integration with LIMS platforms via RESTful API. All logged parameters — setpoint, actual chamber temperature, alarm status, printer activity, and communication heartbeat — are time-stamped with millisecond precision and digitally signed to ensure data integrity during regulatory audits.

Applications

• Bacterial and yeast culture maintenance (e.g., E. coli, S. cerevisiae) at defined physiological temperatures
• Plant seed germination and seedling development studies under controlled photoperiod-independent thermal regimes
• Enzyme activity assays requiring strict thermal stability between 20–40 °C
• Stability testing of diagnostic reagents and biopharmaceutical intermediates per ICH Q1A(R2)
• Environmental simulation for ecotoxicology experiments involving aquatic or soil microflora
• Quality control incubation for food microbiology (APHA, ISO 6579) and water testing (ISO 9308-1)

FAQ

Does the SHH-500L support humidity control?
No — this model is a temperature-controlled biochemical incubator only. Humidity regulation is not integrated; users requiring humidified environments should consider the YSEI SHH-H series or auxiliary steam humidification add-ons.
Can the thermal printer output be disabled or configured for selective logging?
Yes — printer activation, interval, and data fields (e.g., timestamp only vs. full temperature trace) are fully configurable via the front-panel menu or LabLink™ software.
Is the SMS alert system compatible with international cellular carriers?
The GSM module supports quad-band 850/900/1800/1900 MHz frequencies and requires a standard SIM card with active data/SMS service; carrier compatibility must be verified regionally prior to deployment.
What validation documentation is included with purchase?
Standard delivery includes factory calibration certificate, electrical safety test report, and GB/T 28851–2012 conformance statement. IQ/OQ protocols and execution services are available as optional deliverables with lead-time planning.
How is firmware updated, and is version history maintained?
Firmware updates are performed via USB stick using signed binary files; the controller retains a read-only log of all update timestamps, version numbers, and operator IDs for audit readiness.