Zelab Center60 Ultra-Pure Water System (Municipal Tap Water Feed)
| Brand | Zelab |
|---|---|
| Origin | USA |
| Manufacturer Type | Authorized Distributor |
| Origin Category | Imported |
| Model | Center60 |
| Pure Water Grade | Type I (ASTM D1193-20) |
| Resistivity | >10 MΩ·cm at 25°C |
| Heavy Metals & Soluble Silica | <0.01 ppb |
| Total Organic Carbon (TOC) | <3 ppb |
| Microbial Count / Endotoxins | <0.001 EU/mL |
| Particles (>0.1 µm) | <1 particle/mL |
| Production Capacity | 60 L/h (DI water) |
| RO Recovery Rate | ≥95% |
| Input Water Requirement | TDS <200 ppm, 5–45°C, 1.0–4.0 kgf/cm² |
| Power Supply | AC 220 V ±10%, 50 Hz, 240 W |
| Dimensions (L×W×H) | 57×60×150 cm |
| Weight | ~70 kg |
Overview
The Zelab Center60 Ultra-Pure Water System is an integrated, laboratory-grade purification platform engineered for continuous production of Type I ultrapure water from municipal tap feed. Utilizing a dual-stage purification architecture—reverse osmosis (RO) followed by high-capacity deionization (DI)—the system delivers water meeting or exceeding ASTM D1193-20 Type I, NCCLS (now CLSI), and CAP standards for critical applications in analytical chemistry, molecular biology, and pharmaceutical quality control. The core process begins with a certified NSF-compliant pre-treatment train—including sediment and activated carbon filtration—followed by a high-rejection Dow FilmTec™ RO membrane (≥95% salt rejection under standard conditions). Post-RO water passes through a 22-L capacity mixed-bed ion exchange cartridge packed with ultra-high-purity Dow® polisher resins, ensuring stable resistivity >10 MΩ·cm and TOC <3 ppb. A final 0.45 + 0.1 µm PES membrane filter provides end-point bioburden and particulate control. All wetted materials comply with USP Class VI and FDA 21 CFR 177 requirements for contact with purified water.
Key Features
- Integrated 20-L pressurized internal storage tank with optional external tank expansion capability
- Modular spiral-interface pre-filtration cartridges enabling tool-free, leak-free replacement in seconds
- Compact, single-chassis design housing RO, DI, storage, and distribution in one footprint (57 × 60 × 150 cm)
- Large backlit LCD display (240 × 128 pixels, 106 × 57 mm) with animated status indicators and real-time parameter visualization
- Microprocessor-based control system with multi-level menu navigation, automatic fault diagnostics, and event-triggered alarms (low feed pressure, tank full, low water, cartridge exhaustion)
- Three-channel online conductivity/resistivity monitoring: feed water, RO permeate, and final DI product water
- Data logging via RS232 and USB interfaces; stores full-year timestamped water quality records compliant with GLP audit trails
- All fluid-path components—including quick-connect fittings, tubing, and housings—certified to NSF/ANSI Standard 61 for potable water systems
Sample Compatibility & Compliance
The Center60 is validated for use across regulated and research-intensive environments requiring consistent Type I water quality. Its output supports HPLC mobile phase preparation, LC-MS solvent formulation, cell culture media reconstitution, ELISA plate washing, and trace-metal analysis (e.g., ICP-MS sample dilution). The system conforms to ISO 9001 manufacturing controls and is designed to support compliance with FDA 21 CFR Part 11 (via optional secure user authentication and electronic signature modules), USP , EP 2.2.44, and ISO 3696:1987. All consumables—including the 22-L mixed-bed column and terminal PES filter—are supplied with CoA documentation specifying residual metal content, TOC leachables, and endotoxin levels (<0.001 EU/mL).
Software & Data Management
Embedded firmware enables fully automated operation with no manual intervention required during normal runtime. The system logs date/time-stamped values for inlet conductivity, RO rejection rate, DI resistivity, tank level, and cartridge usage percentage—exportable as CSV via USB. Audit trail functionality meets GLP requirements, recording operator ID (when configured), alarm events, calibration actions, and maintenance interventions. Optional PC software (Zelab AquaTrack™) provides trend analysis, predictive cartridge life estimation, and customizable report generation aligned with internal SOPs or external inspection protocols (e.g., ANAB, ISO/IEC 17025).
Applications
- Feed water for ultrapure water systems (e.g., as pretreatment for 18.2 MΩ·cm polishing loops)
- Rinsing of precision glassware and volumetric equipment prior to trace analysis
- Preparation of electrophoresis buffers, PCR master mixes, and hybridization solutions
- Mobile phase and standard diluent preparation for HPLC, UPLC, and GC-MS
- Final rinse in semiconductor wafer cleaning processes (Class 100 cleanroom compatible)
- Supply source for hydrogen generators, environmental test chambers, and humidity control units
- Pharmaceutical process water for non-sterile API synthesis and stability study support
FAQ
What inlet water quality is required for optimal performance?
City tap water with TDS ≤200 ppm, temperature between 5–45°C, and pressure of 1.0–4.0 kgf/cm² is recommended. Higher TDS or chlorine residuals may reduce RO membrane lifespan and increase DI column consumption.
Does the system meet regulatory requirements for pharmaceutical water use?
The Center60 produces water suitable for Purified Water (PW) applications per USP and EP 2.2.44. For Water for Injection (WFI), additional distillation or nanofiltration is required per pharmacopoeial monographs.
How is cartridge exhaustion determined and reported?
The system calculates remaining service life based on cumulative flow volume, measured resistivity decay, and real-time ion loading models—displayed as a percentage on the LCD and logged with timestamps.
Can the system be integrated into a building-wide water network?
Yes—via optional booster pump and remote monitoring interface (Modbus RTU or Ethernet/IP), enabling centralized supervision across multiple Center-series units in core facilities or CMC labs.
