Synthesizer
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| Brand | Cytiva |
|---|---|
| Origin | Sweden |
| Model | ÄKTA oligosynt™ |
| Type | Fully Automated Solid-Phase Oligonucleotide Synthesizer |
| Synthesis Scale Range | 40 nmol to 1 µmol |
| Reagent Delivery Precision | ≤2% RSD |
| System Footprint | 600 × 650 × 700 mm (W × D × H) |
| Integrated Sensor Suite | Pressure, Mass Flow, Temperature, UV Absorbance, Conductivity |
| Compliance | Designed for GLP/GMP-aligned process development environments |
| Brand | CEM |
|---|---|
| Origin | USA |
| Manufacturer Status | Authorized Distributor |
| Origin Category | Imported |
| Model | CleavagePro |
| Amino Acid Addition | Automated |
| Reagent Addition | Automated |
| Synthesis Scale | 1–10 μmol |
| Reaction Vessel Count | 48 |
| Reaction Vessel Capacity Options | 15 mL / 50 mL |
| Brand | CEM |
|---|---|
| Origin | USA |
| Model | Liberty Lite 2.0 |
| Amino Acid Addition | Automated |
| Reagent Addition | Automated |
| Synthesis Scale | 0.005–5 mmol |
| Reactor Count | 4 |
| Reactor Volume Range | 10–125 mL |
| Brand | CEM |
|---|---|
| Origin | USA |
| Manufacturer Status | Authorized Distributor |
| Origin Category | Imported |
| Model | Liberty Prime 2.0 |
| Quotation | Upon Request |
| Amino Acid Delivery | Automated |
| Reagent Delivery | Automated |
| Synthesis Scale | 0.0005–5 mmol |
| Number of Reactors | 3 |
| Reactor Volume Range | 10–125 mL |
| Syringe Pump Accuracy | ±0.01 mL |
| Crude Peptide Purity | >70% |
| Brand | CEM |
|---|---|
| Origin | USA |
| Manufacturer Status | Authorized Distributor |
| Origin Category | Imported |
| Model | Liberty PRO |
| Pricing | Upon Request |
| Amino Acid Delivery | Automated |
| Reagent Delivery | Automated |
| Synthesis Scale | 15–1000 mmol |
| Reactor Count | 3 |
| Reactor Volume Options | 3 L, 8 L, 15 L (max. 15 L capacity) |
| Crude Peptide Yield per Batch | Up to 1 kg |
| Synthesis Purity | ≥99% |
| Temperature Control | NIST-Traceable Internal Sensor |
| Stirring Modes | Mechanical Agitation + N₂ Sparging |
| Regulatory Compliance | cGMP-Compliant Materials & Architecture |
| Key Patented Technologies | CarboMAX™ Coupling, HE-SPPS (High-Efficiency Solid-Phase Peptide Synthesis), No-Wash Deprotection/Coupling |
| Core Patents | US7393920 |
| Software Compliance | FDA 21 CFR Part 11, Audit Trail, Electronic Signatures, Role-Based Access Control |
| Validation Documentation | FAT, IQ/OQ, FDS/SDS, Leachables & Extractables Reports, ATEX Hazard Analysis |
| Brand | CEM |
|---|---|
| Origin | USA |
| Model | LibertyBlue 2.0 |
| Amino Acid Delivery | Automated |
| Reagent Delivery | Automated |
| User Authentication | Password + Facial Recognition |
| Audit Trail | Yes |
| Synthesis Scale | 0.005–5 mmol |
| Reactor Count | 4 |
| Reactor Volume Range | 10–125 mL |
| Brand | CEM |
|---|---|
| Origin | USA |
| Manufacturer Status | Authorized Distributor |
| Origin Category | Imported |
| Model | RAZOR |
| Amino Acid Addition | Automated |
| Reagent Addition | Automated |
| Operator Authentication | Password + Facial Recognition |
| Audit Trail | Yes |
| Brand | CS Bio |
|---|---|
| Origin | USA |
| Model | CS536 Series |
| Synthesis Scale | Pilot-scale |
| Reactor Volume Range | 50 mL to 1 L |
| Stirring Options | 180° Tilt-based Mixing or Overhead Stirring |
| Intended Use | Process Development & Scale-up Studies |
| Distribution Status | Authorized Distributor (Non-OEM) |
| Brand | CS Bio |
|---|---|
| Origin | USA |
| Manufacturer Type | Authorized Distributor |
| Origin Category | Imported |
| Model | CSBIO II |
| Price Range | USD 42,000 – 70,000 |
| Brand | Cytiva |
|---|---|
| Origin | Sweden |
| Manufacturer Type | Authorized Distributor |
| Origin Category | Imported |
| Model | ÄKTA oligosynt™ |
| Price Range | USD 14,000 – 140,000 (est.) |
| Principle | Electrochemical Phosphoramidite Synthesis |
| Type | High-Throughput Benchtop Synthesizer |
| Synthesis Scale | 10 µmol – 12 mmol |
| Brand | Cytiva |
|---|---|
| Origin | Sweden |
| Instrument Type | High-Throughput |
| Synthesis Scale Range | 10–1800 µmol |
| Explosion-Proof Design | Yes |
| Industrial-Grade Components | Yes |
| Regulatory Compliance | GMP-Ready, Supports FDA 21 CFR Part 11 & EU Annex 11 |
| Software Platform | UNICORN® v7.x or later |
| Scalability | Linear lab-to-commercial scale-up |
| Annual Production Capacity | Up to hundreds of kilograms (kg/yr), extendable to metric tons under continuous operation |
| Brand | Cytiva |
|---|---|
| Origin | Sweden |
| Model | OligoProcess™ |
| Synthesis Scale | 10–1800 mmol per run |
| Regulatory Compliance | FDA 21 CFR Part 11, GMP-ready architecture |
| Software Platform | UNICORN 7.x or later |
| Column Technology | Flow-through synthesis columns (compatible with ÄKTA oligopilot plus and OligoPilot 400) |
| Construction | Industrial-grade, explosion-proof certified components |
| Application Scope | Clinical-phase development through commercial-scale cGMP manufacturing |
| Brand | Dilun Bio |
|---|---|
| Origin | Beijing, China |
| Manufacturer Type | Authorized Distributor |
| Product Origin | Domestic (China) |
| Model | 686 |
| Quotation | Upon Request |
| Amino Acid Delivery | Automated |
| Reagent Delivery | Automated |
| Synthesis Scale | ≥0.3 mol |
| Reaction Vessel Count | 4 |
| Reaction Vessel Capacity Options | 20/50 mL, 50/100 mL, 150/300 mL, 300/500 mL |
| Reactor Volume Range | 20–2000 L |
| Reactor Material | 304 stainless steel shell with 316L stainless steel lining |
| Solvent Port Count | ≤9 |
| Stirring Mode | Mechanical agitation |
| Amino Acid Activation Vessel Material | 304 SS shell / 316L SS lining |
| Piperidine Buffer Vessel Material | 304 SS shell / 316L SS lining |
| Explosion Protection Rating | Exia IIC T4 GB |
| Power Supply | 220/380 V AC |
| Brand | Gyros Protein Technologies |
|---|---|
| Origin | USA |
| Manufacturer Type | Original Equipment Manufacturer (OEM) |
| Import Status | Imported |
| Model | Symphony® X 24-Channel Fully Automated Peptide Synthesizer |
| Amino Acid Delivery | Automated |
| Reagent Delivery | Automated |
| Synthesis Scale per Reactor | 5 µmol – 1.0 mmol |
| Total Maximum Capacity | 24 mmol |
| Number of Reactors | 24 |
| Reactor Volumes | Disposable Plastic Vessels – 10 mL, 45 mL |
| Brand | CEM |
|---|---|
| Origin | USA |
| Manufacturer Status | Authorized Distributor |
| Origin Category | Imported |
| Model | MultiPep 1 (SLi) / MultiPep 2 (RSi) |
| Amino Acid Delivery | Automated |
| Reagent Delivery | Automated |
| User Authentication | Password + Facial Recognition |
| Audit Trail | Yes |
| Synthesis Scale | 0.001–0.3 mmol |
| Brand | JIZHOU |
|---|---|
| Origin | Jiangsu, China |
| Manufacturer Type | Authorized Distributor |
| Product Origin | Domestic (China) |
| Model | JZ-Series Fixed-Volume Stainless Steel Oligo Synthesis Columns |
| Volumes | 1.2 mL, 6.3 mL, 12 mL, 24 mL, 48 mL |
| Material | ASTM F138-certified 316L stainless steel |
| Column Dimensions | As per JZ-1001 to JZ-1005 specification table |
| Filter Type | Sintered metal frit (porosity: 5–10 µm) |
| Pressure Rating | ≤10 bar (static), compatible with standard phosphoramidite chemistry delivery systems |
| Sealing | Dual O-ring (FKM/Viton®) static seal assembly |
| Brand | JIZHOU |
|---|---|
| Origin | Jiangsu, China |
| Manufacturer Type | Authorized Distributor |
| Country of Origin | China |
| Model | Oligo Series |
| Pressure Rating | 2 MPa |
| Internal Diameter Options | 35 mm, 50 mm, 70 mm, 100 mm, 140 mm, 200 mm, 350 mm |
| Bed Height Range | 0–150 mm (standard), 50–300 mm (long-bed variants) |
| Column Volume Range | 10–100 mL (for 35 mm ID) |
| Weight | 2–270 kg (model-dependent) |
| Material Compatibility | Resistant to anhydrous acetonitrile, dichloromethane, pyridine, triethylamine, and other reagents used in phosphoramidite-based solid-phase oligonucleotide synthesis |
| Brand | Cytiva |
|---|---|
| Origin | Sweden |
| Manufacturer Type | Authorized Distributor |
| Origin Category | Imported |
| Model | OligoPilot |
| Pricing | Available Upon Request |
| Brand | PSI |
|---|---|
| Origin | USA |
| Model | DL-PSI419 |
| Amino Acid Delivery | Automated |
| Reagent Delivery | Automated |
| Synthesis Scale per Channel | 2.5–20 mmol |
| Number of Reaction Vessels | 2 |
| Vessel Capacities | 0.5 L, 1 L, 2 L (jacketed) |
| Syringe Pump Accuracy | ±0.1 mL |
| Synthesis Purity | ≥99.5% |
| Solvent Flow Rate | 200 mL/min |
| Brand | PSI Scientific |
|---|---|
| Origin | USA |
| Manufacturer Type | Authorized Distributor |
| Origin Category | Imported |
| Model | EX870B |
| Amino Acid Delivery | Automated |
| Reagent Delivery | Automated |
| Audit Trail | Yes |
| Synthesis Scale | Configurable (0.1–5 mmol typical batch range) |
| Reactor Count | 1 |
| Reactor Type | Hydraulic-actuated, jacketed stirred-tank reactor with integrated resin handling |
| Brand | PSISCIENTIFIC |
|---|---|
| Origin | USA |
| Model | E860 / EX860 |
| Synthesis Scale | 62.5–250 mmol |
| Reaction Vessel Volume | 5–20 L (configurable) |
| Heating | Optional |
| Coupling Efficiency | >99% |
| Stirring Mechanism | 180° Vertical Inversion |
| Compliance | FDA 21 CFR Part 11, cGMP (US & China), ATEX/IECEx for EX860 |
| Activation Methods | HOBt/DIC, DCC, HBTU, HATU, PyBOP, OxymaPure, etc. |
| Amino Acid Reservoir Capacity | 250 mL – 2 L |
| Stirring Speed | 0–100 rpm (infinitely variable) |
| Dimensions | 1800 × 1020 × 810 mm (W×D×H) |
| [Brand | ACT/Tetras |
|---|---|
| Origin | USA |
| Model | Tetras 106-Channel Peptide Synthesizer |
| Amino Acid Delivery | Automated |
| Reagent Delivery | Automated |
| Synthesis Scale per Reactor | 30–1000 µmol or 0.01–3 g resin |
| Max Reactor Count | ≤106 |
| Reactor Volumes | 6 mL, 25 mL, 40 mL, 60 mL |
| Syringe Pump Accuracy | <1% |
| Synthesis Purity | ≥99.5% |
| Flow Rate | 0.25–1 mL/s] |
| Brand | Sepure Instruments |
|---|---|
| Origin | Jiangsu, China |
| Manufacturer Type | OEM Manufacturer |
| Instrument Type | Low-Throughput Synthesizer |
| Coupling Efficiency | DNA >99% |
| Oligonucleotide Length Range | 5–80 bases |
| Synthesis Scale | 50 µmol – 9 mmol |
| UV Detector Wavelength Range | 200–800 nm (4-channel simultaneous detection) |
| Max Operating Pressure | 2 MPa |
| Pump Type | High-Precision Dual Plunger Pumps |
| Flow Rate | ≤ 2 × 100 mL/min |
| Column Reactor Count | 7 |
| Standard Monomer Inlets | 12 |
| Waste Outlets | 8 |
| System Protection | Inert Gas (N₂/Ar) Purge |
| Power Supply | 220 VAC / 600 W |
| Dimensions (W×H×D) | 583 × 614 × 523 mm |
| Included Accessories | PEEK/PTFE Tubing Kit, Installation Manual, User Manual, Fittings, Basic Tool Set |
| Brand | TSIKER |
|---|---|
| Origin | Beijing, China |
| Manufacturer Type | Direct Manufacturer |
| Origin Category | Domestic (China) |
| Model | 080 |
| Amino Acid Delivery | Fully Automated |
| Synthesis Scale | 0.025–5 mmol |
| Reactor Quantity | 1 |
| Reactor Volume Options | 10 mL, 30 mL, 125 mL, 200 mL |
| Brand | TSIKER |
|---|---|
| Origin | Beijing, China |
| Manufacturer | TSIKER Biotech Co., Ltd. |
| Model | Syn-AJY-5L |
| Pressure Rating | 550 kPa (safety limit) with triple safety protection |
| Max Operating Pressure | 600 kPa (auto rapid vent) |
| Temperature Control Range | Ambient to 90 °C |
| Throughput | Dual 96-well plates (192 oligonucleotide strands per run) |
| Deprotection Efficiency | ≥99% under standard 90 °C / 2 h protocol |
| Dimensions | 600 × 400 × 400 mm (L×W×H) |
| Weight | 40 kg |
| Safety Features | Electronic overpressure alarm, automatic gas cutoff, mechanical pressure relief valve |
| End-of-cycle Alert | Audible tone |
| Brand | TSIKER |
|---|---|
| Origin | Beijing, China |
| Manufacturer | Yes |
| Type | Domestic |
| Model | Syn-CHY-192 |
| Pricing | Upon Request |
| Brand | TSIKER |
|---|---|
| Origin | Beijing, China |
| Manufacturer | Tsingke Biotech Co., Ltd. |
| Type | Low-throughput synthesizer |
| Coupling Efficiency | ≥99% |
| Max. Oligo Length | 200 nt |
| Channels | 12 independent synthesis columns |
| Scale Range | 10 nmol – 100 µmol per column |
| Cycle Time | ≤6 s per coupling step |
| Base Bottle Positions | 10–28 |
| Auxiliary Reagent Positions | 6–9 |
| Dimensions (L×W×H) | 850 × 550 × 1050 mm |
| Weight | 34 kg |
