ZHWY ZWF-2112 Dual-Layer Reciprocating Large-Capacity Temperature-Controlled Orbital Shaker

Overview

The ZHWY ZWF-2112 is a dual-layer, reciprocating orbital shaker engineered for high-capacity, temperature-sensitive biological and bioprocess applications. It operates on the principle of controlled horizontal orbital motion—driven by a precision track mechanism—to ensure uniform mixing, suspension, and aeration of culture media across large-volume vessels. Its full-temperature range (4–60 °C), combined with P.I.D. microprocessor-based environmental scanning control and forced-air convection, enables stable thermal regulation critical for microbial fermentation, cell line expansion, and enzyme kinetics studies. Designed for scalability, the ZWF-2112 supports pilot-scale and early-stage manufacturing workflows in pharmaceutical, biotech, and blood bank environments—particularly where consistent shear profiles and uninterrupted thermal homogeneity are required over extended durations (up to 500 hours).

Key Features

• Dual-layer vertical architecture maximizes floor space efficiency while delivering 543 L total chamber volume and dual 940 × 580 mm stainless-steel shaking platforms
• Reciprocating orbital drive system with adjustable amplitude (0–50 mm) and speed range of 30–240 rpm (±1 rpm accuracy), optimized for gentle yet effective suspension of sensitive cells and viscous media
• P.I.D. intelligent controller with LCD backlit display showing real-time setpoints and measured values for temperature, speed, time, and amplitude
• Comprehensive safety architecture: over-temperature acoustic/visual alarm, motor overheat protection, independent power cutoff upon thermal runaway or sensor failure
• Power-loss recovery function resumes pre-interruption operating parameters automatically after AC restoration
• Soft-start acceleration circuitry prevents sample splashing and ensures mechanical stability during ramp-up
• Electrostatically sprayed steel enclosure with tempered glass double-door viewport and ergonomic handle design for routine access and visual monitoring
• Lockable parameter interface prevents unauthorized modification—supports GLP-compliant operational integrity

Sample Compatibility & Compliance

The ZWF-2112 accommodates diverse vessel configurations across both shelves simultaneously: up to 164 × 100 mL flasks, 90 × 250 mL, 76 × 500 mL, 48 × 750 mL, or 44 × 1000 mL Erlenmeyer flasks. Its ±0.1 °C temperature resolution and ≤±0.1 °C fluctuation (at 37 °C) meet performance expectations for ISO 13485-aligned bioprocess equipment validation. While not certified to IEC 61000-6-3 or UL 61010-1 out-of-box, the unit complies with CE-marking essential requirements for laboratory electrical safety and electromagnetic compatibility when installed per manufacturer-specified ambient conditions (5–25 °C ambient, non-condensing environment). It supports documentation traceability for FDA 21 CFR Part 11–aligned workflows when integrated with validated external data logging systems.

Software & Data Management

The embedded microcontroller records operational history—including start/stop timestamps, temperature/speed deviations, alarm events, and user-access logs—with non-volatile memory retention. Though no proprietary PC software is bundled, RS-232 serial output (optional adapter) enables integration with third-party LIMS or SCADA platforms for automated data capture. All parameter changes are timestamped and attributed to operator ID (via manual entry), satisfying basic audit trail requirements under GLP and GMP Annex 11. Password-protected configuration mode ensures procedural consistency across shifts and operators.

Applications

This shaker is routinely deployed in: aerobic bacterial and yeast fermentation (e.g., E. coli, S. cerevisiae); mammalian suspension culture (CHO, HEK293); blood bag agitation in transfusion medicine; biochemical assay development requiring precise thermal + kinetic control; and stability testing of therapeutic proteins under ICH Q5C conditions. Its robust construction and thermal uniformity (≤±1 °C at 37 °C across entire chamber) make it suitable for ISO/IEC 17025-accredited QC labs performing method validation per USP and EP 2.6.30.

FAQ

What is the maximum load capacity per shelf?
Each 940 × 580 mm platform supports up to 30 kg distributed load, verified at 240 rpm and 50 mm amplitude.
Does the unit support refrigeration below ambient temperature?
No—it provides heating and ambient-plus temperature control only (4–60 °C); active cooling is not integrated.
Can the two shelves operate at different temperatures or speeds?
No—both shelves share identical setpoints; independent control is not available.
Is calibration documentation included?
A factory-issued temperature and speed verification report is provided; users must perform periodic in-house calibration per SOP using NIST-traceable probes.
What maintenance is required for long-term reliability?
Annual inspection of drive belt tension, fan filter cleaning, and verification of door seal integrity are recommended; the brushless AC induction motor requires no scheduled servicing.