LeadFluid TSD01-01 Bidirectional Push-Pull Syringe Pump

Overview

The LeadFluid TSD01-01 Bidirectional Push-Pull Syringe Pump is an electromechanically driven precision fluid delivery system engineered for laboratory-scale continuous and programmable liquid handling. It operates on a closed-loop stepper motor control architecture coupled with high-precision lead screw transmission—utilizing aerospace-grade angular contact bearings instead of conventional bronze bushings—to ensure long-term mechanical stability, minimal backlash, and consistent force transmission over extended operational cycles. Unlike single-direction syringe pumps, the TSD01-01 supports true bidirectional operation: simultaneous or alternating push-and-pull motion across two independently mounted syringes, enabling uninterrupted flow during syringe refill transitions. This capability is critical in applications requiring zero-flow interruption—such as chromatographic solvent delivery, microfluidic perfusion, or sequential reagent dosing in automated assay platforms. Its measurement fidelity is rooted in calibrated volumetric displacement rather than indirect pressure or sensor-based inference, making it suitable for low-viscosity to moderately viscous Newtonian fluids (e.g., aqueous buffers, organic solvents, diluted polymer solutions) under ambient pressure conditions.

Key Features

• Bidirectional dual-syringe architecture supporting injection, withdrawal, alternating push-pull, and continuous infusion modes
• High-resolution 4.3-inch color TFT touchscreen with LF-Touch-OS firmware—enabling intuitive parameter configuration, real-time animated status visualization, and multi-layered workflow navigation
• Adjustable linear force output (>20 kgf max), optimized for compatibility with syringes ranging from 10 µL to 60 mL (including glass, plastic, and luer-lock types)
• Microstepping precision of 0.15625 µm per step, delivering sub-nanoliter per minute resolution at lowest speeds (down to 0.184 nL/min)
• Integrated mechanical stall detection and occlusion alarm system with audible/visual alerts and automatic pump halt upon abnormal load increase
• RS485 serial interface compliant with Modbus RTU protocol for integration into SCADA, PLC, or custom LabVIEW-based control environments
• External TTL-level 24 VDC I/O for hardware-triggered start/stop and direction reversal, synchronized with auxiliary devices (e.g., solenoid valve controllers, optical sensors)
• Full-metal enclosure with electrostatic discharge (ESD)-safe grounding and industrial-grade anti-corrosion powder coating for durability in shared lab environments

Sample Compatibility & Compliance

The TSD01-01 is designed for use with standard Luer-lock and Luer-slip syringes conforming to ISO 8536-4 and ISO 594 specifications. Its flow calibration data—validated using deionized water at 25 °C and atmospheric pressure—is traceable to volumetric displacement principles; users are advised to apply empirical correction factors when operating with non-Newtonian fluids, elevated backpressures (>1 bar), or temperature extremes. While not certified for in vivo or clinical use, the pump meets CE marking requirements for laboratory equipment (2014/30/EU EMC Directive and 2014/35/EU Low Voltage Directive). Its firmware supports audit-ready operation logs when paired with external data acquisition systems compliant with FDA 21 CFR Part 11 guidelines (e.g., electronic signatures, time-stamped event records, and user-access controls).

Software & Data Management

The embedded LF-Touch-OS provides local configuration storage for up to 20 user-defined protocols—including flow rate profiles, volume targets, acceleration/deceleration ramps, and pause intervals. Screen lock mode and silent-key operation minimize accidental input during unattended runs. All operational parameters—including elapsed time, delivered volume, remaining volume, current flow rate, direction indicator, and syringe ID—are displayed concurrently on the main interface with dynamic graphical feedback. For centralized deployment, the RS485 port enables deterministic command-response communication using ASCII or Modbus function codes (e.g., FC03 for register read, FC10 for preset multiple registers). Third-party software integration is supported via documented API commands and open protocol specifications, facilitating synchronization with ELN systems, LIMS, or custom Python/Matlab automation scripts.

Applications

• Chromatography mobile phase delivery in HPLC and UHPLC preparatory setups where pulseless, low-drift flow is essential
• Cell culture media perfusion in bioreactors and organ-on-chip platforms requiring precise nutrient/gas exchange timing
• Calibration and validation of flow sensors and microfluidic flow meters across sub-µL/min regimes
• Automated titration and reagent addition in analytical chemistry workflows governed by GLP-compliant SOPs
• Controlled drug dissolution testing per USP and , particularly for low-dose formulations requiring nanoliter-level dosing accuracy
• Material science applications including controlled deposition of functional inks, hydrogels, or nanoparticle suspensions onto substrates

FAQ

What syringe sizes are supported?
The TSD01-01 accommodates syringes from 10 µL to 60 mL, with preloaded calibration tables for common volumes (25 µL, 100 µL, 1 mL, 5 mL, 10 mL, 20 mL, 30 mL, 60 mL) and support for custom syringe diameter entry.
Does the pump support gradient or variable-rate infusion?
Yes—via programmable multi-segment protocols that allow discrete changes in flow rate, direction, and volume target at defined time points or volume thresholds.
Is remote monitoring possible without physical connection to a PC?
No native Wi-Fi or Ethernet interface is included; however, RS485-to-Ethernet gateways or USB-to-RS485 adapters enable networked access through intermediate industrial gateways or Raspberry Pi-based edge controllers.
How is accuracy verified and maintained over time?
Accuracy is factory-verified using gravimetric methods per ISO 8655-3. Users may perform periodic verification using certified volumetric flasks or balance-based collection tests; no field recalibration tools are provided, but firmware allows manual offset adjustment within ±1% range.
Can the pump operate in hazardous or high-humidity environments?
It is rated for indoor laboratory use only (IP20 enclosure rating); operation in explosive atmospheres, cleanrooms requiring ISO Class 5 compliance, or environments exceeding 80% RH is not recommended without environmental conditioning.