Anyeep RGA 6500 Residual Gas Analyzer (RGA) for Online Small-Molecule Mass Spectrometry
| Brand | Anyeep |
|---|---|
| Origin | Jiangsu, China |
| Manufacturer Type | Direct Manufacturer |
| Country of Origin | China |
| Model | RGA 6500 |
| Pricing | Upon Request |
Overview
The Anyeep RGA 6500 is a compact, high-stability residual gas analyzer engineered for continuous, real-time monitoring of small-molecule gaseous species in industrial process streams, vacuum systems, and research-grade controlled environments. Operating on the principle of quadrupole mass spectrometry with electron ionization (EI), the RGA 6500 delivers rapid, quantitative detection across a nominal mass range of 1–300 Da—optimized for common process gases including H₂, He, O₂, N₂, CO, CO₂, CH₄, H₂O, NH₃, and light hydrocarbons. Its all-metal, stainless-steel vacuum chamber—rated for sustained operation up to 200 °C—minimizes surface adsorption, reduces memory effects, and ensures thermal stability during extended online deployment. The system maintains ultra-high vacuum integrity via a dual-pump architecture: a maintenance-free oil-free diaphragm pump serves as the roughing stage, while a high-speed turbomolecular pump achieves base pressures below 5 × 10⁻⁸ mbar—critical for low-noise detection and high signal-to-background ratio.
Key Features
- All-stainless-steel vacuum chamber with bake-out capability up to 200 °C, enabling consistent desorption control and minimizing condensable residue accumulation
- Open-geometry electron impact (EI) ion source with filament current regulation and emission stabilization—designed for long-term operational stability under variable gas composition
- Monolithic metal double-curvature quadrupole mass filter fabricated from precision-machined electrodes, ensuring mass resolution (M/ΔM ≥ 200 at 10% valley) and long-term mass calibration retention
- Secondary electron multiplier (SEM) detector with selectable gain modes and built-in pulse-counting electronics for sub-femtoamp signal detection sensitivity
- Integrated full-range capacitance manometer (1 × 10⁻⁵ to 1000 mbar) providing real-time vacuum status feedback with traceable NIST-traceable calibration
- Modular inlet configuration supporting both heated stainless-steel transfer lines (up to 350 °C) and fused-silica capillary probes—compatible with high-temperature reactor effluents and corrosive gas matrices
Sample Compatibility & Compliance
The RGA 6500 is validated for direct analysis of non-condensable and low-boiling-point gases without pre-concentration or derivatization. It accommodates sample streams with moisture content ≤ 1000 ppmv and total hydrocarbon loadings up to 10,000 ppmv when operated with appropriate inlet conditioning (e.g., inline particulate filtration and cold trap bypass). The instrument conforms to IEC 61000-6-2 (electromagnetic immunity) and IEC 61000-6-4 (emission) standards. Its mechanical design adheres to ISO 8573-1 Class 4 for compressed air compatibility in auxiliary purge applications. While not certified for hazardous area installation (e.g., ATEX or IECEx), it supports integration into Class 1 Div 2 or Zone 2 process enclosures when deployed with intrinsically safe signal interfaces per ISA-RP12.6.
Software & Data Management
The RGA 6500 is operated via Anyeep’s proprietary RGA Control Suite—a Windows-based application supporting real-time spectral acquisition, multi-point quantitative trending, and user-defined mass fragment libraries. The software implements audit-trail functionality compliant with FDA 21 CFR Part 11 requirements, including electronic signatures, session logging, and immutable data archiving. Raw spectral data are stored in vendor-neutral .mzML format; time-series concentration logs export to CSV or OPC UA-compatible tags for seamless integration into DCS/SCADA platforms (e.g., Siemens PCS7, Emerson DeltaV). Remote diagnostics and firmware updates are supported over Ethernet TCP/IP using Modbus TCP or custom RESTful API endpoints.
Applications
- Real-time leak detection and residual gas profiling in semiconductor vacuum chambers (CVD, PVD, etch tools)
- In-line monitoring of synthesis gas composition (H₂/CO ratio), purge efficiency, and catalyst deactivation indicators in chemical reactors
- Process validation and endpoint determination in lyophilization cycles and vacuum drying systems
- Contamination surveillance in high-purity inert gas supply lines (Ar, N₂, He) used in metallurgy and fiber optics manufacturing
- Qualitative and semi-quantitative off-gas analysis during thermal desorption, TGA-MS coupling, and battery electrolyte decomposition studies
FAQ
What is the typical detection limit for nitrogen (N₂) under standard operating conditions?
The RGA 6500 achieves a minimum detectable partial pressure of approximately 5 × 10⁻¹² mbar for N₂ at unit mass resolution, assuming stable vacuum conditions and optimized SEM gain settings.
Can the RGA 6500 be integrated with existing PLC-based control systems?
Yes—the instrument provides analog 4–20 mA outputs for up to four user-selected masses, along with digital communication via Modbus TCP or optional Profibus DP interface modules.
Is routine filament replacement required, and what is its expected lifetime?
Filament lifetime exceeds 6,000 hours under continuous EI mode with clean, dry gas streams; replacement is field-serviceable and requires no vacuum break.
Does the system support automated calibration routines?
A two-point mass calibration (using known peaks at m/z 28 and m/z 44) is supported via software wizard; full mass scale calibration is recommended quarterly or after major thermal cycling events.
What vacuum accessories are included by default?
The standard configuration includes the oil-free diaphragm pump, turbomolecular pump with controller, full-range vacuum gauge, and associated CF-35 flanges and sealing hardware.

