DRETOP ZYC-150G High-Temperature Incubator Shaker

Overview

The DRETOP ZYC-150G High-Temperature Incubator Shaker is an engineered solution for applications requiring precise thermal control combined with robust orbital agitation under elevated temperature conditions. Unlike standard incubator shakers limited to ≤60°C, the ZYC-150G extends operational capability up to 150°C—enabling accelerated stability studies, high-temperature enzyme kinetics, thermophilic microbial cultivation, polymerization reaction monitoring, and heat-induced protein denaturation assays. Its air-jacketed heating architecture ensures uniform temperature distribution across dual stainless-steel shelves while minimizing thermal lag and overshoot. The system operates on orbital shaking principle (26 mm circular orbit), generating consistent shear profiles suitable for suspension cultures, sol-gel transitions, and heterogeneous catalytic reactions. Designed for GLP-compliant laboratories, it supports traceable, repeatable operation in R&D, QC, and pilot-scale bioprocess development environments.

Key Features

• Microprocessor-based PID temperature and speed control with ±0.1°C temperature accuracy and ±1 rpm speed regulation—validated per ISO/IEC 17025 calibration protocols;
• Dual independent stainless-steel shelves (400 × 370 mm each) with reinforced load capacity for up to 24 × 250 mL flasks or equivalent configurations;
• High-efficiency air-jacketed heating system with insulated double-wall construction, achieving stable setpoint maintenance at 150°C with <±0.3°C spatial uniformity (measured per ASTM E2234);
• Brushless DC motor drive delivering constant torque across full speed range (0–300 rpm), eliminating carbon wear, electrical noise, and maintenance intervals;
• Intelligent start-up algorithm with programmable ramp acceleration to prevent sample splashing during initiation—critical for low-viscosity media and high-fill-ratio vessels;
• Integrated safety architecture including over-temperature cut-off (dual independent sensors), over-speed shutdown, timer auto-stop, power-fail recovery, and parameter lockout with password protection;
• Ergonomic 4.3-inch backlit LCD interface with angled viewing angle, real-time display of actual vs. set temperature, rpm, elapsed time, and alarm status;
• Electrostatically coated steel exterior and electropolished 304 stainless-steel interior chamber—resistant to corrosion, compatible with alcohol-based disinfectants and routine autoclave-grade cleaning.

Sample Compatibility & Compliance

The ZYC-150G accommodates standard laboratory vessels—including Erlenmeyer flasks (50–5000 mL), test tubes, microtiter plates (with optional adapter), and custom bioreactor bags—via interchangeable clamping systems (fixed bottle clamps, universal spring clips, tube racks, and irregular-neck adapters). Its 150°C upper limit permits use with silicone-sealed glassware and high-temp polymer containers rated to ≥180°C. The unit complies with IEC 61010-1:2010 for laboratory equipment safety and meets electromagnetic compatibility requirements per EN 61326-1. For regulated environments, audit trails are supported via optional USB data logging (timestamped temperature/rpm/time records), aligning with FDA 21 CFR Part 11 data integrity expectations when paired with validated software.

Software & Data Management

While the base model operates via standalone front-panel control, optional USB interface enables direct connection to Windows-based PCs for real-time data streaming and post-run analysis. Exported CSV files contain second-resolution timestamps, measured temperature, actual rpm, and system status flags—facilitating integration into LIMS or electronic lab notebooks (ELN). Firmware supports user-defined parameter profiles (up to 10 memory slots), each storing temperature setpoint, speed, timer duration, and ramp rate. All settings persist through power cycling; parameter modification requires administrator-level access code to prevent accidental deviation from SOP-defined conditions.

Applications

• Thermophilic bacterial and archaeal culture (e.g., Geobacillus stearothermophilus, Pyrococcus furiosus) under controlled aeration;
• Accelerated stability testing of pharmaceutical formulations per ICH Q1A(R3) guidelines at elevated temperatures;
• High-temperature enzymatic hydrolysis (cellulases, amylases) and immobilized enzyme reactor optimization;
• Solid-phase synthesis and solvent-mediated crystallization where thermal agitation improves nucleation kinetics;
• Material science workflows including nanoparticle synthesis (e.g., solvothermal metal oxide formation) and polymer crosslinking studies;
• Environmental microbiology assays involving compost thermophiles or activated sludge acclimation at >70°C.

FAQ

What is the maximum recommended operating temperature for continuous use?
The ZYC-150G is rated for sustained operation at 150°C; however, prolonged exposure above 120°C may reduce seal longevity in certain flask closures—verify vessel compatibility per manufacturer specifications.
Can the unit maintain temperature uniformity with both shelves loaded?
Yes. Thermal mapping per ASTM E2234 confirms ≤±0.5°C deviation across all shelf positions at 100°C and 150°C under full-load conditions.
Is refrigeration available on this model?
No. The ZYC-150G is a heating-only air-jacketed system. For sub-ambient capability, refer to DRETOP’s ZYC-100BR or ZYC-400WR series with compressor-based cooling.
Does the shaker support external communication protocols (e.g., RS-485, Ethernet)?
Not natively. Communication is limited to USB 2.0 for data export. Modbus or Ethernet integration requires third-party gateway hardware and custom firmware adaptation.
Are validation documents (IQ/OQ/PQ templates) provided?
DRETOP supplies factory calibration certificates and basic OQ checklists. Full GMP-compliant IQ/OQ/PQ documentation packages are available upon request and require site-specific execution by qualified personnel.