DRETOP ZYC-400B Air-Bath Orbital Shaker

Overview

The DRETOP ZYC-400B Air-Bath Orbital Shaker is a precision-engineered laboratory instrument designed for simultaneous temperature-controlled incubation and orbital agitation of biological and biochemical samples. Unlike water-bath shakers, this air-bath system employs forced-air convection within an insulated chamber to deliver rapid, uniform thermal distribution across the entire platform—eliminating condensation risks and enabling stable operation at elevated temperatures up to 60°C. Its orbital motion (26 mm diameter) generates gentle yet effective mixing ideal for suspension cultures, enzyme assays, hybridization reactions, and microbial fermentation studies where shear-sensitive cells or fragile aggregates require consistent, low-turbulence agitation. The unit integrates incubator and shaker functionalities into a single compact footprint—optimized for space-constrained biosafety cabinets, core facilities, and GLP-compliant QC laboratories.

Key Features

• Microprocessor-based PID temperature and speed control ensures long-term stability: ±0.1°C temperature accuracy and ±1 rpm rotational repeatability over full operating range.
• Three-dimensional eccentric cam drive mechanism enables smooth acceleration from standstill, minimizing sample splashing and ensuring mechanical integrity during startup and deceleration phases.
• Brushless DC motor delivers maintenance-free operation with consistent torque output across 0–300 rpm, eliminating carbon brush wear and electromagnetic interference typical of brushed motors.
• Stainless steel interior chamber and vibration platform resist corrosion from repeated sterilization cycles and chemical exposure—compatible with 70% ethanol, hydrogen peroxide vapor, and common lab disinfectants.
• Large tempered glass observation window with integrated LED illumination allows real-time visual monitoring without opening the chamber door—preserving thermal and environmental integrity.
• Comprehensive safety architecture includes over-temperature cutoff, overspeed shutdown, timed auto-stop, power-failure recovery, and user-accessible parameter encryption to prevent unauthorized configuration changes.

Sample Compatibility & Compliance

The ZYC-400B accommodates standard laboratory vessels including Erlenmeyer flasks (50–5000 mL), test tubes, microcentrifuge tubes, and custom bioreactor vessels via interchangeable clamping systems: universal spring clips, fixed bottle holders, tube racks, and irregular-shape adapters. Its RT+5°C to 60°C operating envelope meets ASTM E1827–22 requirements for incubator performance verification and supports ISO 13485-certified medical device manufacturing environments. When equipped with optional UV-C germicidal lamps (254 nm), the unit complies with USP guidelines for environmental monitoring in aseptic processing areas. All firmware and data logging functions adhere to FDA 21 CFR Part 11 principles—including electronic signature support, audit trail generation, and immutable timestamped records when paired with DRETOP’s validated USB export protocol.

Software & Data Management

The embedded control system features non-volatile memory for automatic parameter restoration after power interruption. Real-time operational data—including setpoints, actual temperature, instantaneous RPM, elapsed time, and alarm history—are continuously displayed on the backlit LCD interface. Optional USB connectivity enables direct download of time-stamped CSV logs containing ≥10,000 data points per session; exported files are compatible with Excel, MATLAB, and LIMS platforms for statistical process control (SPC) analysis. Firmware updates are performed via secure USB flash drive—no network connection required—to maintain air-gapped compliance in regulated environments. Data integrity is preserved through cyclic redundancy check (CRC) validation during transfer and write operations.

Applications

This shaker serves critical roles across academic research, pharmaceutical development, and industrial bioprocessing. It supports bacterial growth kinetics under defined thermal-aerobic conditions (e.g., E. coli expression optimization), mammalian cell suspension culture in serum-free media, ligand-binding assays requiring precise thermal ramping, and environmental microbiology studies involving soil or wastewater enrichment. In quality control labs, it fulfills USP / microbial enumeration protocols requiring standardized agitation during membrane filtration or broth dilution steps. Its wide speed range and stable temperature profile also enable method development for accelerated stability testing per ICH Q1A(R3), particularly for temperature-sensitive protein formulations.

FAQ

What is the maximum load capacity of the ZYC-400B platform?
The 920 × 500 mm platform supports up to 25 kg distributed evenly—sufficient for four 2 L flasks or sixteen 500 mL vessels using factory-supplied universal clamps.
Does the unit comply with electromagnetic compatibility (EMC) standards?
Yes—certified to IEC 61326-1:2023 for laboratory equipment, with conducted and radiated emissions tested per CISPR 11 Group 1 Class B limits.
Can the shaker operate unattended for extended periods?
With its 0–999 hour timer, thermal runaway protection, and auto-restart function, it is validated for continuous 7-day operation under supervised laboratory conditions.
Is remote monitoring supported?
No Ethernet or Wi-Fi interface is built-in; however, periodic USB log extraction enables offline trend analysis and regulatory submission documentation.
How is temperature uniformity verified across the platform?
DRETOP provides a factory calibration certificate showing ≤±0.8°C spatial deviation at 37°C (measured at nine grid points per ISO 17025-accredited procedure).