Huchuan HWZ-300 Microplate Shaker

Overview

The Huchuan HWZ-300 Microplate Shaker is an engineered platform for precise, reproducible orbital agitation of microtiter plates in life science laboratories. It operates on the principle of controlled circular motion—specifically, a 3 mm orbit diameter—generating consistent shear and mixing forces across all wells without splashing or cross-contamination. Designed for compatibility with standard ANSI/SLAS-format microplates (including 96-well, 384-well, deep-well, and multi-well cell culture plates), the HWZ-300 supports applications ranging from ELISA assay development and antibody incubation to cell-based kinetic studies and reagent homogenization. Its brushless DC motor ensures stable rotational output across the full speed range (200–2000 rpm), eliminating commutator wear, electromagnetic interference, and maintenance downtime—critical for unattended overnight or multi-hour protocols.

Key Features

• Digital LCD interface with real-time display of speed, elapsed time, remaining time, and operational status.
• Brushless DC motor delivering low-noise (<45 dB(A)), low-vibration performance with high torque consistency at all setpoints.
• Precise speed control in 10 rpm increments, enabling method optimization for sensitive biological assays requiring defined agitation intensity.
• Programmable timer supporting durations from 1 minute to 99 hours 59 minutes—or infinite continuous operation for extended incubation-shaking cycles.
• Integrated LED status strip providing immediate visual feedback: green (running), yellow (paused), red (fault or error condition).
• Acoustic signaling system: audible beep upon program completion; distinct alarm tone during overtemperature, overload, or positional sensor fault detection.
• Tool-free quick-release plate clamping mechanism—engineered for rapid loading/unloading of two stacked microplates with mechanical stability across the full speed range.
• Switch-mode power supply (DC 24 V / 2 A) ensuring stable voltage regulation, broad input tolerance, and thermal resilience during prolonged use.

Sample Compatibility & Compliance

The HWZ-300 accommodates two full-size microplates simultaneously—including flat-bottom, U-bottom, V-bottom, and deep-well formats—without stacking adapters or alignment fixtures. Its rigid aluminum-alloy chassis and precision-machined platform minimize resonance at high speeds, preserving well integrity and minimizing edge effects. While not certified to IEC 61000-6-3 (EMC) or ISO 13485 out-of-the-box, its electrical architecture adheres to fundamental safety and emissions guidelines aligned with CE-conformant laboratory equipment design. The device supports GLP- and GMP-aligned workflows through deterministic timing, non-volatile parameter retention, and auditable operational states (start/stop/timer expiry/fault events). It is suitable for use in ISO 17025-accredited testing labs where instrument qualification includes documented verification of speed accuracy (±2% full scale), timer fidelity (±0.1%), and orbit consistency.

Software & Data Management

The HWZ-300 operates as a standalone hardware-controlled shaker with no embedded firmware upgrade path or USB/Bluetooth connectivity. All parameters are configured locally via tactile membrane keys and validated in real time on the LCD. For integration into electronic lab notebooks (ELNs) or LIMS environments, users may log settings manually using the device’s unique identifier (model + serial prefix, engraved on rear panel) and timestamped run records. Though it lacks native 21 CFR Part 11 compliance features (e.g., user authentication, audit trail), its deterministic behavior—combined with external documentation practices—permits validation per FDA guidance for “low-risk” ancillary lab equipment used in non-clinical research and QC release testing.

Applications

• Antibody-antigen binding kinetics in ELISA and lateral flow assay development.
• Cell suspension maintenance during transfection, staining, or viability assays (e.g., MTT, ATP luminescence).
• Homogenization of viscous reagents (e.g., agarose gels, polymerase master mixes, lysate supernatants).
• Enhanced hybridization efficiency in DNA/RNA probe-based assays.
• Accelerated dissolution testing of lyophilized biologics in 96-well format.
• High-throughput screening (HTS) plate conditioning prior to reader measurement.

FAQ

Does the HWZ-300 support temperature control?
No. The HWZ-300 is a dedicated orbital shaker only. It does not include heating or cooling modules. For combined shaking and incubation, consider a microplate shaker-incubator variant.
Can it accommodate 1536-well plates?
No. The platform is dimensionally optimized for ANSI/SLAS-standard plates up to 384-well. 1536-well plates require specialized carriers not supported by this model.
Is calibration traceable to NIST standards?
The unit ships with factory-set speed and timer calibration. Users may verify performance using an external tachometer and stopwatch; however, no NIST-traceable certificate is provided by default.
What maintenance is required?
None beyond periodic cleaning of the platform surface and inspection of the rubber isolation feet. The brushless motor requires no lubrication or brush replacement over its service life.
Is the power supply included?
Yes. A CE-certified 24 V DC switching adapter (input: 100–240 V AC, 50/60 Hz) is supplied with each unit.