METTLER TOLEDO ML54T/02 Analytical Balance

Overview

The METTLER TOLEDO ML54T/02 Analytical Balance is a precision laboratory instrument engineered for high-reliability mass measurement in regulated and non-regulated environments. Based on METTLER TOLEDO’s proven MonoBloc weighing cell architecture, it employs electromagnetic force compensation technology to deliver consistent, traceable, and thermally stable measurements across variable ambient conditions. With a maximum capacity of 52 g and readability of 0.1 mg, the ML54T/02 meets the performance requirements of pharmacopeial methods—including USP and EP 2.1.2—where minimum weight verification, repeatability, and measurement uncertainty are critical. Its compact footprint (290 mm depth × 193 mm height) optimizes bench space without compromising mechanical rigidity or draft protection integrity. The balance is not certified for legal-for-trade applications but is fully compliant with ISO/IEC 17025 calibration traceability frameworks when operated within specified environmental parameters (temperature stability ±2 °C, humidity <80% RH non-condensing).

Key Features

• MonoBloc Weighing Cell: Single-piece, stress-free sensor design minimizes creep and thermal drift, ensuring long-term stability and reproducibility.
• FACT (Fully Automatic Calibration Technology): Integrated temperature-controlled internal calibration routine triggers automatically at predefined intervals or user-defined thresholds, maintaining metrological integrity without manual intervention.
• LevelControl Guidance System: Real-time digital leveling assistant displays visual tilt indicators and step-by-step instructions on the 4.5-inch color touchscreen, reducing setup time and operator dependency.
• MinWeigh Function: Enforces USP-compliant minimum sample weight thresholds; net weight values remain highlighted in red until the measured mass exceeds the preconfigured limit (e.g., 0.16 g typical), preventing out-of-specification results.
• QuickLock Draft Shield: Tool-free, snap-fit glass enclosure with smooth-radius edges enables rapid disassembly and cleaning—critical for GMP-compliant labs handling potent compounds or cross-contamination-sensitive materials.
• Hygienic Construction: Seamless die-cast aluminum base and chemical-resistant ABS housing meet ISO 14644-1 Class 5 cleanroom compatibility criteria; no recessed seams or trapped zones for particulate accumulation.

Sample Compatibility & Compliance

The ML54T/02 supports standard analytical workflows involving powders, granules, liquids, and small solid specimens up to 52 g. Its 90 mm diameter stainless steel pan accommodates common weighing vessels (e.g., aluminum pans, glass vials, crucibles). The balance complies with ISO 9001 quality management system documentation requirements and supports GLP/GMP audit readiness through its built-in ISO logging function: all calibration events, FACT adjustments, level corrections, and parameter changes are timestamped, user-identified, and stored internally for ≥10,000 entries. While not FDA 21 CFR Part 11–enabled by default, audit trails can be exported via USB or RS232 for integration into validated electronic lab notebook (ELN) or LIMS platforms.

Software & Data Management

Data transfer is facilitated through native PC Direct mode—no proprietary software required—enabling seamless export of raw weight values, timestamps, and metadata directly into Excel, LabArchives, or custom databases. USB host capability permits direct printing to compatible label printers or storage to FAT32-formatted flash drives. Optional Bluetooth module (sold separately) allows wireless pairing with tablets or mobile devices running METTLER TOLEDO’s LabX Lite companion app for remote monitoring and batch record capture. All interface protocols adhere to IEEE 488.2 and VISA standards, ensuring interoperability with automated sample handlers and robotic arms in semi-automated QC lines.

Applications

This balance serves core functions in pharmaceutical R&D (API potency assays, excipient blending verification), clinical chemistry (reagent preparation, calibrator dilution), academic research (nanomaterial dosing, catalyst loading), and food safety testing (nutrient fortification validation, allergen threshold analysis). Its fast 2-second stabilization time supports high-throughput gravimetric titration setups and dynamic loss-on-drying (LOD) sequences where repeated tare-and-weigh cycles demand both speed and statistical confidence (RSD ≤ 0.1% at 10 g load).

FAQ

Does the ML54T/02 support external calibration with traceable weights?
Yes—manual external calibration using NIST-traceable Class E2 or better砝码 is supported via the service menu, though FACT internal calibration is recommended for routine operation.
Can the ISO log be exported in CSV format?
Yes—logs are exportable as plain-text or tab-delimited files via USB stick; no encryption or proprietary encoding is applied.
Is the touchscreen operable with nitrile or silicone gloves?
Yes—the capacitive 4.5-inch display responds reliably to gloved fingertips, including low-conductivity materials commonly used in aseptic processing.
What environmental conditions invalidate the stated repeatability specification?
Repeatability of 0.1 mg assumes vibration isolation (optical table or Sorbothane pads), air currents <0.2 m/s, and ambient temperature variation <±0.5 °C over measurement duration.
How often does FACT initiate calibration under default settings?
FACT triggers every 2 hours if temperature change exceeds ±1.5 °C from last calibration point—or immediately upon power-up if ambient deviation exceeds ±3 °C.