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Yi Heng BPH Series Precision Temperature-Controlled Incubator with Multi-Stage Programmable LCD Controller

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Brand Yi Heng (Shanghai)
Origin Shanghai, China
Manufacturer Type Authorized Distributor
Product Origin Domestic (China)
Model BPH Series
Temperature Control Range & Accuracy RT+5°C to 80°C
Temperature Uniformity ±1.5°C (at 37°C test point)
Temperature Resolution / Stability 0.1°C / ±0.2°C
Power Supply AC 220 V, 50 Hz
Operating Ambient Temperature +5°C to +35°C
Standard Shelving 2 adjustable stainless-steel shelves

Overview

The Yi Heng BPH Series Precision Temperature-Controlled Incubator is engineered for consistent, reliable thermal environments essential in cell culture, microbiological growth, enzyme assays, and long-term stability studies. Designed around a robust convection-based thermal management architecture, the BPH series employs a microprocessor-controlled forced-air circulation system with dynamically regulated fan speed—ensuring minimal thermal gradient across the chamber while preventing sample desiccation or mechanical stress on sensitive biological specimens. Unlike static incubators, this model integrates adaptive airflow modulation: fan velocity automatically reduces during temperature stabilization phases to maintain optimal laminar flow conditions aligned with ISO 13408-1 (aseptic processing) and CLSI M22-A3 (microbiological incubation) best practices. The chamber’s mirror-finish stainless-steel interior—featuring seamless, radius-cornered construction—facilitates rapid decontamination and eliminates microbial harborage zones, supporting routine cleaning validation under GLP-compliant laboratory workflows.

Key Features

  • Multi-stage programmable LCD controller supporting up to 7 programs × 9 steps (63 total steps), with configurable ramp rates, dwell times (0–5999 minutes per step), and automatic start/standby/shutdown sequences.
  • Fuzzy PID temperature regulation delivering ±0.2°C stability and 0.1°C resolution; independent over-temperature cut-off circuit with audible/visual alarm ensures fail-safe operation per IEC 61010-1 safety requirements.
  • Intelligent air circulation system: fan speed auto-adjusts based on real-time thermal load—reducing turbulence during steady-state incubation to preserve monolayer integrity in adherent mammalian cultures.
  • Chamber access via dual-layer insulated glass observation window (on select models); 25 mm diameter external port enables integration of external sensors, gas lines, or data loggers without compromising thermal seal integrity.
  • Self-diagnostic interface displays fault codes (e.g., sensor failure, heater open-circuit, fan stall) directly on the main LCD—accelerating root-cause identification during QA/QC audits.

Sample Compatibility & Compliance

The BPH series accommodates standard tissue culture flasks (T25–T225), Petri dishes (up to 150 mm), multi-well plates, and microbiological slants. Its uniform temperature distribution (±1.5°C at 37°C, validated per ASTM E2874–19 Annex A1) meets acceptance criteria for ISO/IEC 17025-accredited testing laboratories. Optional UV-C germicidal irradiation (254 nm, 15 W lamp) provides non-chemical surface decontamination between runs—validated against ATCC 6538 (Staphylococcus aureus) and ATCC 9027 (Bacillus subtilis) spores per ISO 15714. All electrical components comply with CE marking directives (EMC Directive 2014/30/EU, LVD Directive 2014/35/EU) and RoHS 2011/65/EU material restrictions.

Software & Data Management

While the BPH series operates autonomously via its embedded controller, optional connectivity modules enable traceable data governance. The RS-485 interface supports Modbus RTU protocol for integration into LabVantage or Thermo Fisher SampleManager LIMS environments. USB host port accepts FAT32-formatted USB drives for time-stamped temperature logging (1-second sampling interval, 30-day buffer). Output files conform to CSV format compliant with FDA 21 CFR Part 11 requirements when paired with validated third-party software—supporting electronic signature, audit trail, and data integrity controls required for GMP-regulated bioprocessing labs.

Applications

  • Mammalian and insect cell line maintenance (e.g., HEK293, CHO-K1, Sf9) requiring stable 37°C environments with low thermal drift.
  • Bacterial and fungal cultivation per CLSI M02-A12 and ISO 8199 standards, including aerobic/anaerobic pre-enrichment protocols.
  • Enzyme kinetics studies where precise thermal ramping (e.g., 25°C → 37°C → 42°C) must be synchronized with spectrophotometric readouts.
  • Stability testing of diagnostic reagents and pharmaceutical intermediates per ICH Q1A(R2) guidelines under accelerated conditions (40°C/75% RH with external humidity module).
  • Educational use in undergraduate life science laboratories—designed for high uptime (>99.5% annual availability) and intuitive menu navigation minimizing operator training time.

FAQ

What is the maximum allowable ambient temperature for continuous operation?

The unit is rated for uninterrupted use at ambient temperatures between +5°C and +35°C, as specified in IEC 60068-2-1 (cold) and IEC 60068-2-2 (dry heat) environmental testing standards.

Can the incubator be validated for IQ/OQ/PQ protocols?

Yes—dimensional drawings, factory calibration certificates (NIST-traceable PT100 sensors), and temperature mapping templates are provided upon request to support installation qualification (IQ), operational qualification (OQ), and performance qualification (PQ) documentation.

Is CO₂ compatibility available for this model?

The BPH series is a dedicated temperature-controlled incubator without integrated CO₂ regulation; for CO₂-dependent applications, Yi Heng’s BB150 series is recommended.

How often does the UV lamp require replacement?

The optional UV-C lamp has a rated service life of 5,000 hours; intensity decay is monitored via built-in radiometer output (calibration certificate included).

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