HengAo HTR-02 Adjustable-Angle Vortex Mixer

Overview

The HengAo HTR-02 Adjustable-Angle Vortex Mixer is an engineered solution for reproducible, low-shear orbital mixing of liquid samples in tubes, vials, and small-volume containers. Unlike fixed-angle vortexers, the HTR-02 employs a precision-machined rotational drive system that delivers controlled, continuous orbital motion—generating gentle yet effective convective mixing without splashing or foaming. Its core principle relies on eccentric rotation of the sample platform around a central axis, inducing uniform fluid circulation within vertically oriented or tilted vessels. Designed for routine use in QC laboratories, clinical diagnostics, molecular biology prep workflows, and pharmaceutical stability testing, the HTR-02 supports GLP-aligned documentation practices through stable speed control and mechanical repeatability across shifts and operators.

Key Features

• Infinitely adjustable tilt angle (0° to 90°) enables optimization of mixing efficiency for viscous, particulate-laden, or density-stratified samples—particularly critical for sediment resuspension in ELISA plate wells or cell pellet reconstitution.
• Digital LED display provides real-time feedback of actual rotational speed (0–60 rpm), eliminating reliance on analog dials or external tachometers.
• Modular tube holder system accepts standard 10–50 mm diameter vessels; optional quick-release adapters support conical tubes, PCR strips, microcentrifuge tubes (0.2–15 mL), and custom labware via standardized M6 threaded mounting points.
• Corrosion-resistant stainless-steel drive shaft and clamp assembly ensure long-term dimensional stability under repeated exposure to aqueous buffers, ethanol, and mild organic solvents.
• Thermally insulated motor housing and low-noise brushless DC drive maintain consistent torque output over extended operation (>8 hrs continuous duty cycle) with minimal heat transfer to samples.
• Integrated overload protection and auto-shutdown upon abnormal current draw safeguard both instrument longevity and operator safety per IEC 61000-4-5 surge immunity requirements.

Sample Compatibility & Compliance

The HTR-02 accommodates heterogeneous sample types including aqueous suspensions, glycerol-diluted reagents, blood serum aliquots, bacterial culture broths, and nanoparticle dispersions. Its low-speed orbital action minimizes shear-induced denaturation of proteins or aggregation of liposomes—making it suitable for pre-analytical sample homogenization prior to HPLC injection or flow cytometry analysis. The device complies with CE marking directives for electromagnetic compatibility (EN 61000-6-3) and immunity (EN 61000-6-2). While not certified to ISO/IEC 17025 calibration standards, its speed stability (±1.5 rpm at setpoint) meets internal method validation thresholds for ASTM D4097 (standard practice for mixing liquid samples prior to viscosity measurement) and USP environmental sampling preparation protocols.

Software & Data Management

The HTR-02 operates as a standalone hardware platform with no embedded firmware or network interface. All operational parameters are set manually via front-panel controls; no software installation, cloud connectivity, or data logging capability is included. This architecture ensures compliance with air-gapped laboratory environments governed by FDA 21 CFR Part 11 Annex 11 requirements for non-automated equipment. For audit-ready workflows, users may integrate the mixer into electronic lab notebooks (ELN) via manual entry of run logs—including date/time stamp, speed setting, tilt angle, vessel type, and duration—supporting traceability under ISO 15189 and GMP Annex 11 documentation frameworks.

Applications

• Resuspension of lyophilized reagents and centrifuged cell pellets in diagnostic assay preparation.
• Homogenization of immunoassay standards and calibrators prior to pipetting to reduce inter-vial variability.
• Pre-mixing of multi-component reaction cocktails for PCR setup and NGS library preparation.
• Stabilization of emulsions and colloidal suspensions during formulation development in R&D labs.
• Uniform dispersion of magnetic beads in automated extraction platforms where precise agitation timing is required.
• Environmental microbiology workflows involving soil eluate or water filter eluent homogenization prior to membrane filtration.

FAQ

Is the HTR-02 compatible with sterile hood operation?
Yes—the unit’s compact footprint (220 × 180 × 160 mm) and absence of exhaust vents or external cooling fans allow safe placement inside Class II biosafety cabinets without airflow disruption.
Can the tilt angle be locked at intermediate positions?
Yes—a dual-knob mechanical locking system secures the platform at any selected angle between 0° and 90° with ±0.5° repeatability across repeated adjustments.
What maintenance is required for long-term reliability?
No scheduled lubrication or recalibration is needed; periodic cleaning of the clamp groove and shaft with 70% isopropanol is recommended to prevent polymer residue buildup from adhesive tube labels.
Does the HTR-02 meet vibration isolation requirements for sensitive instrumentation nearby?
When mounted on a granite benchtop or anti-vibration pad, the unit generates <0.5 µm peak-to-peak displacement at 60 rpm—within acceptable limits for adjacent analytical balances (per ASTM E177) and optical microscopes.
Are replacement holders available for non-standard tube geometries?
Yes—HengAo offers OEM-designed holders for 96-well plates (orbital mode only), cryovials with O-ring seals, and tapered glass test tubes (12–25 mm OD); all feature identical M6 mounting interface and load-rated spring tension.