Sartorius Proline Bottle-top Dispenser

Overview

The Sartorius Proline Bottle-top Dispenser is a precision-engineered, autoclavable liquid handling instrument designed for accurate, repeatable, and contamination-free dispensing of reagents, standards, solvents, and buffers directly from laboratory bottles. Based on positive displacement piston technology, the Proline series eliminates reliance on air displacement—ensuring consistent volumetric delivery regardless of liquid viscosity, volatility, or vapor pressure. Its robust architecture integrates borosilicate glass tubing, chemically inert fluoropolymer seals (PTFE/FEP), and high-strength PEEK components, enabling reliable operation across aggressive organic solvents, strong acids, bases, and aqueous solutions. Designed for routine QC laboratories, analytical workflows, and regulated environments, the Proline meets foundational requirements for traceability, reproducibility, and operator safety in ISO/IEC 17025 and GLP-compliant settings.

Key Features

• Autoclavable construction (121 °C, 20 minutes, 1 bar)—fully validated for repeated sterilization without performance degradation.
• Five calibrated models covering a continuous volume range from 0.01 mL to 50 mL, each with engraved, parallax-free scale and fine-adjustment micrometer mechanism for sub-milliliter resolution.
• Smooth, low-friction piston glide ensures ergonomic operation and minimizes user fatigue during high-frequency dispensing tasks.
• Integrated leak-proof safety valve with positive shut-off prevents drips, post-dispense leakage, and accidental over-delivery—even when tilted or paused mid-cycle.
• 360° rotatable dispensing head enables optimal positioning for ergonomic access and reduced risk of cross-contamination in crowded hoods or multi-vessel setups.
• Modular design supports full field disassembly: glass tube, piston, seals, and valve body are individually replaceable—extending service life and reducing total cost of ownership.
• Comprehensive thread adapter kit (GL32 through GL80) ensures compatibility with standard laboratory bottle necks—including narrow-mouth, wide-mouth, and HDPE/PP/PC containers.

Sample Compatibility & Compliance

The Proline dispenser demonstrates broad chemical compatibility, validated against common laboratory solvents including acetone, methanol, acetonitrile, hydrochloric acid (up to 6 M), sodium hydroxide (up to 2 M), and hydrogen peroxide (30%). All wetted materials comply with USP Class VI and FDA 21 CFR §177.2440 for food-contact applications. While not inherently compliant with 21 CFR Part 11, the device supports audit-ready documentation when used with controlled dispensing logs, calibration records, and maintenance logs maintained per internal SOPs. It conforms to ISO 8655-3 (2022) for piston-operated volumetric apparatus and supports verification protocols aligned with ASTM E542 and ISO/IEC 17025 Clause 6.4.2.

Software & Data Management

The Proline is a standalone mechanical instrument with no embedded electronics or software interface. However, its design facilitates integration into digital lab workflows: calibration certificates include traceable serial numbers and as-found/as-left data; maintenance logs can be linked to LIMS or ELN entries via barcode-scannable labels on each unit; and dispensing volumes are manually recorded using standardized forms compatible with electronic signature capture under GxP conditions. Optional accessories—including calibrated test flasks and gravimetric verification kits—enable routine accuracy checks per ISO 8655-6.

Applications

• Preparation of calibration standards and reference solutions in analytical chemistry (HPLC, IC, AAS).
• Accurate dispensing of hazardous or volatile reagents in fume hoods—reducing exposure risk and improving containment.
• Buffer and media preparation in cell culture and molecular biology labs, where sterility and consistency are critical.
• QC sampling in pharmaceutical manufacturing, supporting batch release testing per USP and Annex 15.
• Teaching laboratories requiring durable, intuitive, and safe liquid handling tools for undergraduate and graduate instruction.

FAQ

Is the Proline dispenser suitable for use with hydrofluoric acid (HF)?

No. HF attacks both borosilicate glass and PTFE components; alternative dispensers with sapphire or Hastelloy-wetted parts are required.
Can the glass tube be replaced in the lab without specialized tools?

Yes—the glass tube is secured with a single retaining ring and can be swapped using only a supplied hex key and clean gloves.
Does Sartorius provide certified calibration services for the Proline series?

Yes—accredited calibration services (ISO/IEC 17025) are available globally, including full uncertainty budgets and NIST-traceable certificates.
What is the recommended recalibration interval under routine lab use?

Annual verification is advised; more frequent checks (e.g., quarterly) are recommended in high-throughput or regulated environments.
Are extension tubes available with graduated markings?

Standard extension tubes are unmarked; however, custom-labeled versions with volume indicators can be ordered as special configurations upon request.