BENDER YDH-4-125 Aviation-Grade Dry Shipper Liquid Nitrogen Container (4L Capacity, 125mm Neck Opening)

Overview

The BENDER YDH-4-125 is an aviation-certified dry shipper liquid nitrogen container engineered for safe, compliant, and thermally stable transport of biological specimens at cryogenic temperatures. Unlike traditional liquid-phase dewars, this unit employs a gas-phase storage architecture—utilizing high-efficiency cryo-absorbent material housed in a stainless-steel mesh compartment—to maintain sample zones consistently below –190 °C without free liquid nitrogen in the storage chamber. This design eliminates risks associated with liquid sloshing, spillage, or pressure buildup during rapid acceleration, turbulence, or orientation changes—critical requirements for air cargo, high-speed rail logistics, and inter-laboratory courier services. Its vacuum-insulated double-walled aluminum construction meets GB/T 5458–2012 specifications for low-temperature biological transport containers and supports short-term holding (up to 4 days) under ambient conditions without refilling.

Key Features

• Vacuum-integrated cryo-insulation system delivering uniform thermal stability across the entire sample zone (±0.5 °C variation within the 4 L internal volume)
• 125 mm wide neck opening enabling rapid, tool-free access to cryoboxes and large-format blood bags while maintaining structural integrity during handling
• Aerospace-grade anodized aluminum body with high-adhesion epoxy-polyester coating for corrosion resistance, mechanical durability, and surface hardness (≥6H pencil hardness per ISO 15184)
• Dual-compartment internal architecture: upper sample chamber separated from lower cryo-absorbent layer via precision-welded 316L stainless-steel mesh (pore size: 150 µm), preventing particulate migration into specimen storage areas
• Integrated lift bucket with ergonomic grip and calibrated depth markings for reproducible sample positioning
• Locking lid assembly with dual O-ring sealing and tamper-evident latch mechanism, compatible with IATA Packing Instruction 650 when used with optional certified transport case

Sample Compatibility & Compliance

The YDH-4-125 accommodates standardized cryogenic formats including 25- and 100-slot cryoboxes (ISO/IEC 17025-compatible dimensions), individual cryovials (0.5–5.0 mL), and up to six 50 mL blood bags mounted on rigid carriers. All internal contact surfaces are electropolished and passivated per ASTM A967 to ensure biocompatibility and minimize organic residue retention. The unit conforms to GB/T 5458–2012 for performance, safety, and labeling of biological liquid nitrogen containers. When equipped with the optional IATA-certified transport case and temperature monitoring module, it satisfies regulatory prerequisites for air transport of Category B biological substances (UN3373) under ICAO Technical Instructions and EU Regulation (EC) No. 185/2010.

Software & Data Management

While the base YDH-4-125 operates as a passive cryogenic transport device, integration with the optional Bluetooth-enabled temperature alarm module enables real-time logging of internal chamber temperature (range: –200 °C to +50 °C; resolution: 0.1 °C) and ambient pressure. Data is timestamped and exportable in CSV format via companion mobile application (iOS/Android), supporting audit-ready records aligned with GLP and 21 CFR Part 11 principles—including user authentication, electronic signature capture, and immutable data trails. Firmware updates and calibration verification logs are retained locally on-device memory for traceability.

Applications

• Transport of peripheral blood mononuclear cells (PBMCs), stem cell suspensions, and primary tissue explants between clinical collection sites and central processing labs
• Short-haul distribution of quality-controlled reference standards and proficiency testing materials in external quality assessment (EQA) programs
• Field deployment for biobanking initiatives requiring temporary off-site stabilization prior to long-term archival in liquid-phase LN₂ tanks
• Support of decentralized diagnostic workflows, including rapid turnaround molecular testing where sample integrity must be preserved across multi-modal transit legs (e.g., phlebotomy site → mobile lab van → regional sequencing center)
• Compliance-driven shipment of biospecimens under ISO 20387:2018 (biobanking) and MIABIS 2.0 metadata standards

FAQ

Is the YDH-4-125 approved for air transport under IATA regulations?
Yes—when used with the optional IATA-certified transport case and configured with the temperature alarm module, the unit complies with Packing Instruction 650 for Category B biological substances.
Can the cryo-absorbent material be replaced or regenerated?
The proprietary absorbent matrix is pre-charged and sealed during manufacturing; replacement requires factory service and vacuum reconditioning—no field regeneration is supported.
What is the expected service life of the vacuum insulation layer?
Rated for ≥5 years under normal handling conditions, validated per GB/T 5458–2012 accelerated aging protocols (1000 thermal cycles, –196 °C ↔ +25 °C).
Does the unit support integration with laboratory information management systems (LIMS)?
Raw temperature log files (CSV) are interoperable with common LIMS platforms via automated ingestion scripts; direct API connectivity is not available on the base model.
Are custom labeling or serialization options available for institutional procurement?
Yes—laser-engraved asset tags, QR-coded inventory identifiers, and institution-specific color-coding are offered as OEM services upon request.