Xiangyi HT150R High-Speed Benchtop Refrigerated Centrifuge
| Brand | Xiangyi |
|---|---|
| Origin | Hunan, China |
| Manufacturer Type | Direct Manufacturer |
| Product Category | Domestic |
| Model | HT150R |
| Instrument Type | Benchtop Centrifuge |
| Speed Range | High-Speed (10,000–30,000 rpm) |
| Function | Refrigerated Centrifuge |
| Configuration | Fixed-Angle Rotor |
| Target Applications | Biomolecular Separation |
| Maximum Capacity | 12 × 5 mL |
| Maximum Speed | 15,000 rpm |
| Maximum RCF | 21,532 × g |
| Dimensions (W × D × H) | 300 × 460 × 260 mm |
| Display | 5-inch HD Capacitive Touchscreen |
| Acceleration Steps | 11 |
| Deceleration Steps | 12 (including one customizable step) |
| Programmable Protocols | 100 user-defined methods with custom naming |
| Stepwise Centrifugation | Up to 5 sequential programs per run |
| Pre-cooling | User-configurable & scheduled pre-chill |
| Data Logging | Automatic runtime and fault event logging |
| Drive System | AC Brushless Frequency-Controlled Motor |
| Refrigeration | Inverter-Driven Compressor with Adaptive Sleep Mode |
| Energy Reduction vs. Conventional Units | ~40% |
Overview
The Xiangyi HT150R is a high-speed benchtop refrigerated centrifuge engineered for precision biomolecular separation in space-constrained laboratory environments. Designed around a compact footprint (300 × 460 × 260 mm), it delivers up to 21,532 × g RCF at 15,000 rpm—optimized for nucleic acid purification, protein pellet recovery, organelle isolation, and small-volume cell lysate clarification. Its refrigeration system employs an inverter-driven compressor that dynamically modulates cooling output based on thermal load and ambient conditions, enabling stable temperature control from –20 °C to +40 °C during operation. Unlike fixed-frequency compressors, this architecture eliminates thermal overshoot and reduces mechanical stress, contributing to extended service life and improved long-term temperature stability (< ±1 °C at 4 °C, per ISO 13720:2019 verification protocol). The HT150R operates under a brushless AC motor drive—eliminating carbon brush wear, electrical arcing, and particulate contamination—making it suitable for GMP-aligned QC labs where equipment-induced sample interference must be minimized.
Key Features
- 5-inch high-resolution capacitive touchscreen interface with intuitive parameter entry, real-time dual-display of setpoints and actual values (speed, temperature, time, RCF), and responsive haptic feedback.
- Programmable multi-step centrifugation: up to five discrete protocols can be chained into a single run sequence—enabling automated density gradient fractionation or staged pelleting without manual intervention.
- 100 user-named method storage with editable metadata (e.g., “Plasmid_Purif_Routine_v2”), supporting traceability and procedural consistency across shifts and operators.
- 11 acceleration and 12 deceleration profiles—including one fully customizable ramp rate—to prevent resuspension of delicate pellets during spin-down, particularly critical for ribosomal subunits or membrane vesicles.
- Configurable pre-cooling: users define target temperature, hold duration, and rotor-specific thermal offset; optional scheduled start allows unattended pre-chill initiation prior to operator arrival.
- Comprehensive audit-ready data logging: all operational events—including rotor ID recognition (via embedded RFID tag support), cycle timestamps, temperature/speed deviations >2%, and fault codes—are timestamped and stored internally for ≥10,000 cycles.
Sample Compatibility & Compliance
The HT150R accommodates standard 5 mL conical tubes (e.g., Eppendorf Safe-Lock, Corning Costar) in its 12-position fixed-angle rotor (rotor angle: 45°, radius: 108 mm). It supports common biosafety-rated rotors compliant with IEC 61010-2-020 (Laboratory Equipment Safety) and meets EN 61326-1 electromagnetic compatibility requirements. While not certified to FDA 21 CFR Part 11 out-of-the-box, its firmware architecture supports ALCOA+ principles: all saved methods and logs are immutable upon creation, and user access levels (admin/operator) can be assigned via password-protected login—facilitating alignment with GLP/GMP documentation workflows. Temperature calibration reports and RCF verification certificates (per ISO 21501-3) are available upon request for IQ/OQ validation packages.
Software & Data Management
No external PC software is required for routine operation; however, the HT150R provides USB-C port connectivity for exporting log files (CSV format) and firmware updates. Exported datasets include full metadata: date/time stamp, rotor serial number, program name, actual vs. setpoint deviation history, and error code resolution status. Internal memory retains full operational logs even during power interruption. For integration into LIMS environments, optional RS-485 Modbus RTU communication module enables remote status polling and emergency stop signaling—compatible with LabVantage, STARLIMS, and Thermo Fisher SampleManager platforms.
Applications
- Purification of plasmid DNA, genomic DNA, and RNA from bacterial and mammalian lysates.
- Isolation of extracellular vesicles (exosomes) and microvesicles from serum or conditioned media.
- Clarification of recombinant protein expression supernatants prior to chromatography.
- Preparative separation of mitochondria, nuclei, and lysosomal fractions from tissue homogenates.
- Routine quality control of vaccine adjuvants and nanoparticle-based drug carriers (e.g., lipid nanoparticles).
FAQ
What is the minimum operating temperature, and how quickly does the chamber reach –20 °C?
The HT150R achieves –20 °C in ≤18 minutes when starting from 25 °C with an empty chamber and standard rotor installed.
Does the instrument support rotor auto-recognition?
Yes—optional RFID-enabled rotors allow automatic identification of maximum speed, temperature limits, and safety parameters upon insertion.
Can the centrifuge be integrated into a networked lab infrastructure?
Via optional RS-485 Modbus RTU interface, yes—supporting remote monitoring, batch logging synchronization, and centralized alarm notification.
Is validation documentation available for regulated environments?
Factory-issued IQ/OQ templates, temperature uniformity maps, and RCF verification reports are provided upon order confirmation.
What maintenance intervals are recommended for the inverter compressor and drive motor?
No scheduled maintenance is required for the brushless motor or inverter compressor; annual performance verification (temperature accuracy, speed calibration, vacuum integrity) is advised per ISO/IEC 17025 guidelines.
