Thermo Scientific™ CO2-Resistant Orbital Shaker Model 88881102
| Brand | Thermo Fisher |
|---|---|
| Origin | Shanghai, China |
| Manufacturer Type | OEM Manufacturer |
| Product Category | Domestic (China-sourced) |
| Model No. | 88881102 |
| Price Range | USD 2,800 – 7,000 (FOB Shanghai) |
| Instrument Type | CO₂-Compatible Orbital Shaker |
| Timer Range | 0–99 h 59 min |
| Orbital Speed | 30–300 rpm |
| Orbit Diameter | 19 mm |
| Temperature Range (ambient operation) | 4°C–60°C (requires external incubation environment) |
| Platform Configuration | Single platform (no stackable or multi-tier plates included by default) |
Overview
The Thermo Scientific™ CO2-Resistant Orbital Shaker Model 88881102 is an engineered solution for continuous, low-heat, high-reliability agitation of biological samples inside CO₂-controlled environments—particularly standard humidified CO₂ incubators. Unlike conventional shakers that rely on belt-driven or brushed DC motor systems, this unit employs a brushless DC motor coupled with magnetic drive transmission, eliminating mechanical wear, belt degradation, and particulate shedding. Its core design addresses two critical constraints in cell culture workflows: sustained operation under 20% CO₂ atmosphere and exposure to >95% relative humidity—conditions known to accelerate corrosion and compromise electronic integrity in non-specialized equipment. The shaker operates without internal temperature regulation; instead, it is designed for passive thermal integration within externally controlled incubation chambers (e.g., 37°C, 5% CO₂), maintaining stable orbital motion while contributing <0.8 W of convective heat load—verified per IEC 61000-3-2 harmonic emission testing.
Key Features
- Magnetic drive architecture eliminates belts, gears, and carbon brushes—ensuring zero maintenance over 20,000+ hours of continuous operation and eliminating contamination risk from particulate abrasion.
- Corrosion-resistant construction: 316L stainless steel housing, electropolished mounting surfaces, and conformal-coated PCBs rated IP54 for condensation resistance under 95% RH at 37°C.
- Dedicated external LED controller (IP65-rated) with membrane keypad enables parameter setting—including speed, time, and auto-restart—without opening the incubator door, minimizing environmental disturbance.
- Low thermal signature: Surface temperature rise ≤1.2°C above ambient during 300 rpm operation at 37°C, validated via thermographic imaging (ASTM E1934-19).
- Modular platform interface supports universal clamping for standard flask holders (Erlenmeyer, baffled, roller bottles), microplate adapters (96-/384-well), and custom fixtures via M4 threaded inserts.
Sample Compatibility & Compliance
The shaker accommodates vessels ranging from 25 mL culture flasks to 5 L bioreactor bags when mounted on compatible carriers. It complies with ISO 13485:2016 requirements for manufacturing infrastructure and undergoes full functional validation per IQ/OQ protocols prior to shipment. While not certified as a medical device, its materials and surface finish meet USP Class VI polymer specifications where applicable. All electrical components adhere to IEC 61010-1:2010 for laboratory equipment safety. For regulated environments (GMP/GLP labs), optional audit-trail-enabled firmware (v2.3+) supports 21 CFR Part 11-compliant electronic records when paired with Thermo Fisher’s ChronoLog™ data gateway.
Software & Data Management
The standalone controller provides real-time display of setpoint vs. actual speed (±1 rpm accuracy), elapsed time, and remaining runtime. Optional RS-485 Modbus RTU interface enables integration into LabVantage, STARLIMS, or custom SCADA systems for centralized monitoring. Firmware updates are performed via micro-USB port using signed binaries verified against SHA-256 checksums. Data logging (speed, time, fault codes) is retained onboard for ≥12 months without power, meeting ALCOA+ principles for raw data integrity.
Applications
- Suspension mammalian cell culture (CHO, HEK293) in vented-cap flasks under 5% CO₂/37°C conditions.
- Microbial growth kinetics studies requiring extended agitation in high-CO₂ anaerobic chambers (up to 20% CO₂).
- Antibody production workflows involving transient transfection in serum-free media with precise orbital control.
- Stem cell expansion on microcarriers within humidified incubators—where vibration isolation and thermal neutrality are critical.
- Non-CO₂ applications including reagent mixing, immunoassay plate shaking, and solubility screening at controlled temperatures (4–60°C ambient).
FAQ
Can this shaker operate inside a standard CO₂ incubator without modification?
Yes. It is fully rated for continuous operation at 5–20% CO₂ and 90–95% RH at temperatures up to 60°C ambient—no enclosure or gas purge required.
Is calibration traceable to NIST standards?
Speed calibration is performed using a NIST-traceable optical tachometer (Fluke 80PK-12), with certificate provided upon request.
Does the shaker support programmable ramping or multi-step protocols?
No. It implements fixed-speed, single-stage timing only. Multi-step sequences require external PLC or third-party controller integration via Modbus.
What is the maximum load capacity per platform?
3.5 kg uniformly distributed (tested per ISO 10816-3 vibration severity limits at 300 rpm).
Are spare parts and service manuals available internationally?
Yes. Full technical documentation, exploded diagrams, and RoHS-compliant spare kits (motor assembly, controller PCB, platform mount) are available through Thermo Fisher’s Global Service Portal (Order Code: SHK-SVC-88881102).
