LuXiangYi TGL-16M Benchtop High-Speed Refrigerated Centrifuge

Overview

The LuXiangYi TGL-16M Benchtop High-Speed Refrigerated Centrifuge is engineered for precision separation of biological macromolecules—including nucleic acids, proteins, subcellular organelles, and viral particles—under controlled thermal conditions. Utilizing a brushless DC motor and microprocessor-based control architecture, the instrument delivers high rotational stability, low mechanical vibration, and consistent speed accuracy (±30 rpm) across its operational range up to 16,000 rpm. Its refrigeration system employs an imported high-efficiency compressor and environmentally compliant R134a refrigerant, enabling rapid cooling to −20 °C and precise temperature maintenance within ±1 °C throughout extended runs. Designed for routine use in clinical diagnostics, academic research laboratories, and biotechnology QA/QC workflows, the TGL-16M meets foundational requirements for GLP-compliant sample preparation where thermal integrity and reproducible g-force application are critical.

Key Features

• Brushless DC motor drive ensures extended service life, minimal heat generation, and quiet operation (<65 dB[A])
• Intuitive digital interface with real-time rpm/RCF conversion and dual-unit display for immediate parameter verification
• Programmable acceleration/deceleration profiles: nine selectable ramp curves to minimize shear-induced damage during pelleting of sensitive biomaterials
• Comprehensive safety architecture including electronic lid lock, overspeed protection, overtemperature cutoff, and automatic fault diagnostics with audible/visual alerts
• Auto-memory function stores up to nine user-defined protocols, supporting repeatable method execution without manual reconfiguration
• Robust aluminum alloy rotor chamber with corrosion-resistant interior coating for long-term reliability under repeated sterilization cycles

Sample Compatibility & Compliance

The TGL-16M supports a broad spectrum of centrifugation formats via interchangeable rotors and adapters. Standard configurations include fixed-angle rotors for microtubes (0.2–2.2 mL), conical tubes (5–15 mL), and centrifuge bottles (50 mL), as well as swing-bucket carriers for 48-well microplates. All rotors are dynamically balanced and certified to ISO 15197:2015 standards for mechanical integrity at maximum rated speeds. The unit complies with IEC 61010-1:2012 for laboratory electrical safety and incorporates thermal management features aligned with CLSI EP17-A2 guidelines for temperature-controlled centrifugation in clinical specimen processing. While not FDA 21 CFR Part 11–validated out-of-the-box, its programmable parameters and audit-ready protocol logging support integration into GMP-aligned documentation systems when paired with external electronic lab notebook (ELN) platforms.

Software & Data Management

The TGL-16M operates independently without proprietary software dependency; all settings—including time (1 min to 9 h 59 min), temperature (−20 °C to +40 °C), speed (100–16,000 rpm), and acceleration/deceleration profiles—are configured directly via front-panel controls. Each run logs timestamped operational data (start/end time, final temperature, achieved RCF, rotor ID) into non-volatile memory. Export functionality is not embedded, but users may manually record protocol IDs and performance metrics for inclusion in laboratory information management systems (LIMS) or quality records. For regulated environments, optional third-party validation packages are available to establish IQ/OQ documentation per ASTM E2500-13 and ISO/IEC 17025:2017 requirements.

Applications

• Purification of plasmid DNA and genomic DNA from bacterial lysates using silica-membrane or phenol-chloroform extraction workflows
• Isolation of exosomes and extracellular vesicles from cell culture supernatants and biofluids (serum, plasma, urine)
• Clarification of protein expression lysates prior to affinity chromatography or SDS-PAGE analysis
• Preparation of PBMCs and granulocyte fractions from whole blood using density gradient media
• Routine sedimentation of PCR plates post-amplification to prevent droplet evaporation and cross-contamination
• Stabilization of enzyme assays requiring cold-stage centrifugation to halt catalytic activity

FAQ

What is the maximum relative centrifugal force (RCF) achievable with the TGL-16M?

The instrument achieves a maximum RCF of 17,800 × g at 16,000 rpm with the standard 50 mL rotor configuration.
Does the TGL-16M support continuous temperature monitoring during runtime?

Yes—real-time chamber temperature is continuously displayed and actively regulated throughout the run duration.
Can the centrifuge be used for radioactive or hazardous samples?

It is not certified for containment of volatile radionuclides or biosafety level 3 (BSL-3) agents; appropriate secondary containment and rotor sealing must be verified by the end user per institutional biosafety protocols.
Is rotor imbalance detection built into the control system?

The unit includes automatic imbalance sensing that halts operation if vibration exceeds ISO 1940-1 Grade 6.5 thresholds, preventing mechanical damage.
Are replacement rotors and adapters available through international distributors?

Yes—BIORIDGE-certified rotors, buckets, and tube adapters are distributed globally under part numbers traceable to ISO 9001:2015 manufacturing certification.