L550 Desktop High-Capacity Centrifuge by Lu Xiangyi (BIORIDGE)
| Brand | Lu Xiangyi / BIORIDGE |
|---|---|
| Origin | Shanghai, China |
| Model | L550 |
| Instrument Type | Benchtop Centrifuge |
| Speed Range | 0–5500 rpm |
| Max RCF | 5310 × g |
| Max Capacity | 4 × 500 mL |
| Rotor Configuration | Horizontal (Swing-Out) |
| Application Class | Cell & Bacterial Separation |
| Speed Accuracy | ±30 rpm |
| Timer Range | 1 min–99 h 59 min |
| Noise Level | <65 dB(A) |
| Dimensions (L×W×H) | 460 × 540 × 340 mm |
| Net Weight | 31 kg |
| Power Supply | AC 220 V, 50 Hz, 20 A |
Overview
The L550 Desktop High-Capacity Centrifuge by Lu Xiangyi (BIORIDGE) is an engineered solution for routine and high-throughput sedimentation-based separation in life science laboratories. Designed around a brushless AC frequency-controlled motor and microprocessor-based control architecture, the L550 delivers stable rotational dynamics at speeds up to 5500 rpm—generating a maximum relative centrifugal force (RCF) of 5310 × g. Its horizontal (swing-out) rotor configuration supports large-volume sample processing, making it suitable for primary isolation steps in clinical diagnostics, cell culture harvesting, serum/plasma preparation, bacterial pellet collection, and downstream nucleic acid or protein workflows. Unlike ultra-high-speed or refrigerated models, the L550 operates at ambient temperature and is optimized for robustness, operational simplicity, and long-term reliability in non-cryogenic, low-to-medium speed applications.
Key Features
- Microprocessor-controlled system with real-time monitoring of rpm and RCF, enabling instant unit conversion and parameter validation during operation.
- High-torque AC frequency drive ensures consistent acceleration/deceleration profiles and minimal mechanical drift—even under full-load conditions (4 × 500 mL).
- Intuitive touch-panel interface with LCD display; supports programmable run protocols (up to 10 user-defined methods), each storing speed, time, acceleration/deceleration ramp profiles, and automatic recall on power-up.
- Electronic door interlock with auto-locking lid mechanism and dual-safety verification—prevents operation unless rotor chamber is fully sealed and balanced within tolerance.
- Comprehensive safety suite: overspeed protection, imbalance detection, overtemperature warning (motor housing), and fault-code-driven audible/visual alerts for immediate diagnostic response.
- Customizable ramp control: 10 preconfigured acceleration and deceleration curves allow fine-tuning of shear-sensitive protocols—critical for fragile cell types, organelle isolations, or viscous biological matrices.
Sample Compatibility & Compliance
The L550 accommodates a broad range of standard laboratory vessels via interchangeable rotors—including conical tubes (15 mL × 12), wide-bore bottles (100 mL × 4 and 500 mL × 4), and 96-well microplate carriers (8 plates per run). All rotors are dynamically balanced and certified for use at rated speeds and loads per ISO 15195:2019 (in vitro diagnostic medical devices – requirements for centrifuges). The instrument meets IEC 61010-1:2010 safety standards for electrical equipment used in laboratory environments. While not intrinsically compliant with FDA 21 CFR Part 11, its programmable method storage, audit-ready parameter logging (via optional RS232/USB data export), and repeatable performance support GLP/GMP-aligned documentation practices when integrated into validated lab workflows.
Software & Data Management
The L550 operates as a standalone instrument with embedded firmware—no external PC or proprietary software required for basic operation. All critical parameters (run ID, date/time stamp, setpoints, actual speed history, and error logs) are retained in non-volatile memory. Optional serial or USB connectivity enables transfer of runtime summaries to laboratory information management systems (LIMS) or Excel-based tracking templates. Firmware updates are performed via secure USB flash drive—ensuring version traceability and minimizing downtime. For regulated environments, users may implement procedural controls (e.g., logbook entries, operator sign-offs) to satisfy ALCOA+ data integrity principles without hardware modification.
Applications
- Clinical labs: Serum separation from whole blood, urine sediment concentration, CSF clarification.
- Biotechnology: Harvesting E. coli, yeast, or mammalian cells prior to lysis; clarifying fermentation broths.
- Academic research: Preparative pelleting for subcellular fractionation, virus concentration, extracellular vesicle enrichment.
- Quality control: Stability testing of suspensions, emulsions, and colloidal formulations in pharmaceutical development.
- Immunology: Isolation of peripheral blood mononuclear cells (PBMCs) using density gradient media (e.g., Ficoll-Paque) in swing-out buckets.
FAQ
What is the maximum tube volume supported by the L550?
The L550 accepts up to four 500 mL centrifuge bottles simultaneously in its standard horizontal rotor—providing a total capacity of 2 L per run.
Does the L550 offer refrigeration?
No—the L550 is a non-refrigerated benchtop centrifuge designed for ambient-temperature operations only.
Can rotor imbalances be automatically detected?
Yes—integrated vibration sensors trigger immediate shutdown and visual alarm if mass asymmetry exceeds safe thresholds during acceleration or steady-state rotation.
Is calibration traceable to national standards?
Speed calibration is performed at factory level using NIST-traceable tachometry; users may perform periodic verification with an external handheld tachometer per ISO/IEC 17025 guidelines.
Are rotors autoclavable?
Aluminum rotors are not autoclavable; they must be cleaned with ethanol or mild detergent and air-dried. Stainless steel adapters (where applicable) are compatible with low-temperature sterilization cycles only.
