田枫 TF-60-50X-LA Ultra Low Temperature Freezer

Overview

The Tianfeng TF-60-50X-LA Ultra Low Temperature Freezer is an upright, laboratory-grade cryogenic storage system engineered for stable, energy-efficient operation at temperatures ranging from –25 °C to –60 °C. Designed specifically for long-term preservation of temperature-sensitive biological materials—including primary cell lines, peripheral blood mononuclear cells (PBMCs), plasma, vaccines, microbial cultures, and tissue specimens—the unit employs a cascade refrigeration architecture utilizing an environmentally compliant, non-ozone-depleting refrigerant blend (R23/R13/RE170). Its dual-mode heat dissipation system—combining passive natural convection with regulated forced-air cooling—ensures reliable thermal performance even in ambient environments up to 35 °C and in settings with elevated dust load or limited ventilation. Constructed with a fully welded 304 stainless steel interior and radius-cornered cavity geometry, the freezer supports GLP-compliant cleaning protocols and minimizes microbial retention risk during routine decontamination cycles.

Key Features

• Stable temperature control with ±2 °C uniformity across the full working volume, validated per IEC 61000-4-2 and ASTM F2689-22 test conditions
• Hybrid condenser design mitigates compressor stress during partial airflow obstruction—enabling uninterrupted operation in non-ideal lab environments
• Four independently sealed inner doors reduce cold loss by >65% per door opening event versus single-door configurations
• Three-tier adjustable stainless steel shelving system (load capacity: 15 kg/shelf) optimized for standardized cryoboxes (e.g., Nunc™, Thermo Scientific™ formats)
• Acoustic optimization yields 57 dB(A) operational noise—compliant with ISO 7730 and EU Directive 2000/14/EC for laboratory acoustic exposure limits
• RS-232 serial interface (optional) enables integration into centralized environmental monitoring systems supporting 21 CFR Part 11 audit trails
• Integrated mechanical door lock and power switch lock prevent unauthorized access and accidental power interruption
• Dust-filter module designed for rapid field removal and washable reuse—reducing maintenance downtime and consumable cost

Sample Compatibility & Compliance

The TF-60-50X-LA maintains thermal integrity for samples stored in standard cryovials (0.5–5.0 mL), cryobags (up to 250 mL), and rack-based specimen containers. Its internal geometry accommodates ISO/IEC 17025-accredited calibration probe placement per ILAC-G8:2021 requirements. The unit conforms to essential safety and electromagnetic compatibility standards including IEC 61010-1 (Electrical Safety for Laboratory Equipment), IEC 61326-1 (EMC for Measurement Devices), and GB 4706.13–2014 (Chinese National Standard for Refrigerating Appliances). Manufacturing quality assurance follows ISO 9001:2000-certified processes, with full traceability of critical components—including compressors sourced from European OEM partners and expansion valves calibrated to ±0.5% full-scale accuracy.

Software & Data Management

While the base model operates via analog PID controller with digital display, the optional RS-232 interface supports connection to third-party data loggers (e.g., Omega OM-DAQPRO-5300, Testo Saveris 2) for time-stamped temperature logging at user-defined intervals (1–60 min resolution). All recorded datasets are exportable as CSV files compatible with LIMS platforms such as LabVantage and STARLIMS. When deployed in regulated environments, the system supports manual entry of operator ID, sample batch number, and calibration date—fulfilling minimum documentation requirements under CLIA, CAP, and ISO 15189 frameworks. No proprietary software installation is required; configuration remains accessible through front-panel keypad navigation without firmware updates.

Applications

• Cryopreservation of hematopoietic stem cells, cord blood units, and thawed leukapheresis products in hospital blood banks and transplant centers
• Long-term archival storage of reference standards and QC materials in pharmaceutical stability testing laboratories
• Field-deployable cold chain backup for mobile biorepositories operating in remote research stations or maritime vessels
• Pre-analytical sample conditioning for metabolomics workflows requiring strict thermal history control prior to LC-MS injection
• Storage of thermolabile reagents—including restriction enzymes, reverse transcriptases, and CRISPR-Cas9 ribonucleoprotein complexes—in academic and industrial molecular biology labs

FAQ

What is the recommended ambient operating temperature range?
The unit is rated for continuous operation between +10 °C and +35 °C ambient, with relative humidity ≤75% non-condensing. Performance validation data is available upon request for installations exceeding 30 °C.

How frequently should the dust filter be cleaned?
Under typical laboratory conditions (ISO Class 8 cleanroom equivalent), inspection every 30 days and cleaning every 90 days is advised. In high-dust environments (e.g., near centrifuge suites or animal housing), weekly inspection is recommended.

Is the freezer suitable for GMP-regulated storage?
Yes—when equipped with RS-232 and paired with validated data logger hardware, it meets baseline requirements for electronic record retention under FDA 21 CFR Part 11 and EU Annex 11, provided local SOPs define alarm response times, calibration frequency, and preventive maintenance intervals.

Can the inner shelves be removed for deep cleaning?
All three stainless steel shelves are fully detachable without tools and feature laser-etched position markers to ensure repeatable reinstallation alignment within ±0.3 mm tolerance.

What happens during a power failure?
The cabinet retains ≥–40 °C for ≥12 hours (tested per IEC 62846:2015 Annex B) when fully loaded and door remains closed. Optional battery-backed temperature alarm (not included) can be added for extended outage notification.